酪氨酸硫酸氢酯 | 146386-55-2

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 酪氨酸类衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 酪氨酸硫酸氢酯
• 英文名称: Tyrosin-O-sulfat
• 英文别名: O-sulfo-tyrosine；(2S)-2-Amino-3-[4-(hydroxysulfonyloxy)phenyl]propanoic acid；2-amino-3-(4-sulfooxyphenyl)propanoic acid
• CAS: 146386-55-2
• 化学式: C₉H₁₁NO₆S
• 分子量: 261.255
• InChiKey: CIQHWLTYGMYQQR-UHFFFAOYSA-N

物化性质

• 密度：
  1.598±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  135
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Use of biodegradable polymers in preventing scale build-up
  申请人：NALCO CHEMICAL COMPANY

  公开号：EP0819653A2

  公开（公告）日：1998-01-21

  A biodegradable scale inhibitor and dispersant is provided. The scale inhibitor includes a copolymer comprising at least one of N-oxygenatedhydrocarbonamide monomers and at least one of amino acid monomers. A method of reducing scale build-up on heating exchanger surfaces that come in contact with an industrial water is provided by adding a copolymer comprising at least one of N-oxygenatedhydrocarbonamide monomers and at least one of amino acid monomers to the water system such as cooling towers.

  提供了一种可生物降解的阻垢剂和分散剂。阻垢剂包括一种共聚物，该共聚物由至少一种 N-氧代烃酰胺单体和至少一种氨基酸单体组成。本发明提供了一种减少与工业用水接触的加热交换器表面积垢的方法，即向冷却塔等水系统中添加由 N-氧代烃酰胺单体和氨基酸单体中的至少一种单体组成的共聚物。
• Method to identify a biomolecular profile
  申请人：Plant Research International B.V.

  公开号：EP1536229A1

  公开（公告）日：2005-06-01

  This invention relates to identifying a biomolecular profile of an organism. In particular, the invention relates to targeted and selected proteomics. Provided is a method for identifying a molecular profile comprising a set of molecules of an organism, said method comprising the steps of: a) providing an organism with at least one heterologous modifying activity capable of tagging at least part of said molecules with at least one tag, preferably a carbohydrate tag, which is otherwise not displayed in said organism, wherein said tagging is regulated by at least one regulatory element; b) isolating the tagged molecules to obtain a library of tagged molecules; and c) characterizing said tagged molecules.

  本发明涉及鉴定生物体的生物分子特征。特别是，本发明涉及靶向和选择蛋白质组学。本发明提供了一种用于识别由生物体的一组分子组成的分子特征的方法，所述方法包括以下步骤： a) 提供一种具有至少一种异源修饰活性的生物体，该活性能够用至少一种标签（最好是碳水化合物标签）标记所述分子的至少一部分，该标签不会在所述生物体中显示，其中所述标记由至少一种调节元件调节；b) 分离标记的分子以获得标记分子库；以及 c) 表征所述标记的分子。
• Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanionic polypeptide for the treatment of aids
  申请人：INSTITUT PASTEUR

  公开号：EP2505210A1

  公开（公告）日：2012-10-03

  This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Said organic molecule comprises a 13 amino acid anionic polypeptide. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.

  本发明涉及一种共轭分子，该共轭分子由来自 CD4 受体的多肽通过连接剂与有机分子耦合而成，本发明还涉及一种共轭分子的制备方法。所述有机分子包括 13 个氨基酸的阴离子多肽。这种共轭分子可用于抗病毒治疗，即艾滋病的治疗。
• METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME
  申请人：Riken

  公开号：EP2584037A1

  公开（公告）日：2013-04-24

  The present invention provides a novel method of producing a recombinant bacterium for production of a non-natural protein, including: (1) expressing tRNA in a bacterium, which tRNA recognizes UAG codon; (2) expressing an aminoacyl-tRNA synthetase in the bacterium, which aminoacyl-tRNA synthetase acylates the tRNA with a non-natural amino acid or an α-hydroxy acid; (3) (i) introducing a DNA construct into the bacterium, which DNA construct is for expressing, in the absence of a release factor for terminating translation at UAG codon, a function of at least one gene selected from the group consisting of genes each of which loses its function when a gene that codes for the release factor is defective and/or introducing an alteration into said at least one gene in a chromosome of the bacterium, which alteration is for expressing the function of said at least one gene in the absence of the release factor; and (4) causing the gene that codes for the release factor in the bacterium to be defective.

  本发明提供了一种生产非天然蛋白质的重组细菌的新方法，包括：(1) 在细菌中表达 tRNA，该 tRNA 识别 UAG 密码子；(2) 在细菌中表达氨基酰-tRNA 合成酶，该氨基酰-tRNA 合成酶用非天然氨基酸或 α-羟基酸酰化 tRNA；(3) (i) 向细菌中导入 DNA 构建体，该 DNA 构建体用于在没有用于在 UAG 密码子处终止翻译的释放因子的情况下表达至少一个基因的功能，该基因选自以下基因组：当编码释放因子的基因有缺陷时，每个基因都会失去其功能；和/或在细菌的染色体中向所述至少一个基因导入改变，该改变用于在没有释放因子的情况下表达所述至少一个基因的功能；(4) 使细菌中编码释放因子的基因出现缺陷。
• HEXAPEPTIDES WITH SULPHATE ESTER GROUPS
  申请人：FISONS CORPORATION

  公开号：EP0495013A1

  公开（公告）日：1992-07-22