原甲酸三氯乙酯 | 18719-58-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 原甲酸三氯乙酯
• 英文名称: trichloroethyl orthoformate
• 英文别名: tris-(2-chloro-ethoxy)-methane；orthoformic acid tris-(2-chloro-ethyl) ester；orthoformic acid tris-(2-chloro-ethyl ester)；Orthoameisensaeure-tris-(2-chlor-aethylester)；tris(2-chloroethyl) orthoformate；Orthoameisensaeure-tris-<β-chlor-ethylester>；2-Chloroethyl orthoformate；1-[bis(2-chloroethoxy)methoxy]-2-chloroethane
• CAS: 18719-58-9
• 化学式: C₇H₁₃Cl₃O₃
• mdl: MFCD00000971
• 分子量: 251.537
• InChiKey: RKHRVKJTCSHZCR-UHFFFAOYSA-N

物化性质

• 沸点：
  293.1℃
• 密度：
  1.272
• 闪点：
  63.9℃

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2909199090

SDS

Name:	Tris (2-chloroethyl) orthoformate Material Safety Data Sheet
Synonym:	Ethane, 1,1',1''-[methylidynetris(oxy)]tris[2-chloro-
CAS:	18719-58-9

Section 1 - Chemical Product MSDS Name:Tris (2-chloroethyl) orthoformate Material Safety Data Sheet
Synonym:Ethane, 1,1',1''-[methylidynetris(oxy)]tris[2-chloro-

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
18719-58-9	Tris (2-chloroethyl) orthoformate	100	242-527-0

Hazard Symbols: XN
Risk Phrases: 20/21/22 36/37/38

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
The toxicological properties of this substance have not been fully investigated.
Inhalation:
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Harmful if inhaled.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible liquid and vapor.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat and flame.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 18719-58-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 157 deg C @ 14mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 63 deg C ( 145.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.472
Molecular Formula: C7H13O3Cl3
Molecular Weight: 251.44

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 18719-58-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Tris (2-chloroethyl) orthoformate - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 18719-58-9: No information available.
Canada
CAS# 18719-58-9 is listed on Canada's NDSL List.
CAS# 18719-58-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 18719-58-9 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  原甲酸三氯乙酯 在 sodium hydride 、 叔丁醇 作用下， 以 乙二醇二甲醚 为溶剂， 生成 Divinyloxymethylformiat
  参考文献：
  名称：

  Scheeren,J.W. et al., Recueil des Travaux Chimiques des Pays-Bas, 1971, vol. 90, p. 1123 - 1128

  摘要：

  DOI：
• 作为产物：
  描述：

  2-氯乙醇 、 原甲酸三甲酯 在 盐酸 作用下， 以 乙醇 为溶剂， 生成 原甲酸三氯乙酯
  参考文献：
  名称：

  Stetter,H.; Reske,E., Chemische Berichte, 1970, vol. 103, p. 639 - 642

  摘要：

  DOI：

文献信息

• COMPOSITION COMPRISING FLUORINE-CONTAINING KETONE
  申请人：Sinochem Lantian Co., Ltd.

  公开号：EP3421105A1

  公开（公告）日：2019-01-02

  Disclosed is a composition comprising: (A) at least one fluorine-containing ketone; and (B) an effective amount of stabilizer which is selected from at least one of the group consisting of an epoxy compound, a nitro compound, a hindered phenolic compound, a β-diketone compound, a phosphite compound, a salicylate compound, a cinnamate compound, a hydroxybenzophenone compound, a hydroxybenzoic acid compound, an alkoxy methane compound, and an organic thio compound. The composition provided by the present invention has stable performance, and can be used as a fire extinguishing agent, a heat transfer medium, etc.

  本发明公开了一种组合物，该组合物包含：(A) 至少一种含氟酮；(B) 有效量的稳定剂，该稳定剂选自环氧化合物、硝基化合物、受阻酚类化合物、β-二酮化合物、亚磷酸酯化合物、水杨酸盐化合物、肉桂酸盐化合物、羟基二苯甲酮化合物、羟基苯甲酸化合物、烷氧基甲烷化合物和有机硫化合物中的至少一种。本发明提供的组合物性能稳定，可用作灭火剂、传热介质等。
• Composition comprising fluorine-containing ketone
  申请人：Sinochem Lantian Co., Ltd

  公开号：US10953256B2

  公开（公告）日：2021-03-23

  Disclosed is a composition comprising: (A) at least one fluorine-containing ketone; and (B) an effective amount of stabilizer which is selected from at least one of the group consisting of an epoxy compound, a nitro compound, a hindered phenolic compound, a β-diketone compound, a phosphite compound, a salicylate compound, a cinnamate compound, a hydroxybenzophenone compound, a hydroxybenzoic acid compound, an alkoxy methane compound, and an organic thio compound. The composition provided by the present invention has stable performance, and can be used as a fire extinguishing agent, a heat transfer medium, etc.

  本发明公开了一种组合物，该组合物包含：(A) 至少一种含氟酮；(B) 有效量的稳定剂，该稳定剂选自环氧化合物、硝基化合物、受阻酚类化合物、β-二酮化合物、亚磷酸酯化合物、水杨酸盐化合物、肉桂酸盐化合物、羟基二苯甲酮化合物、羟基苯甲酸化合物、烷氧基甲烷化合物和有机硫化合物中的至少一种。本发明提供的组合物性能稳定，可用作灭火剂、传热介质等。
• Process for producing solid polyurethane moldings
  申请人：——

  公开号：US20030078360A1

  公开（公告）日：2003-04-24

  Solid polyurethane moldings having high inherent rigidity, thin walls and a complex geometry are produced. These polyurethane moldings can be produced by reacting a selected polyisocyanate with a selected compound having groups that are capable of reacting with isocyanate groups by means of the casting process which is a simple and inexpensive processing technology.

  固体聚氨酯模塑件具有高固有刚度、薄壁和复杂的几何形状。这些聚氨酯模塑件可通过浇铸工艺使选定的多异氰酸酯与选定的化合物发生反应而制成，选定的化合物具有能与异氰酸酯基团发生反应的基团，浇铸工艺是一种简单而廉价的加工技术。
• Gross,H.; Costisella,B., Journal fur praktische Chemie (Leipzig 1954), 1969, vol. 311, p. 571 - 576
  作者：Gross,H.、Costisella,B.

  DOI：——

  日期：——
• Nakagawa,Y. et al., Chemical and pharmaceutical bulletin, 1972, vol. 20, p. 2209 - 2214
  作者：Nakagawa,Y. et al.

  DOI：——

  日期：——

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