N,N-diethyl-2-oxo-6-phenyl-4-(2-(2,6,6-trimethylcyclohex-2-enyl)vinyl)cyclohex-3-enecarboxamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N,N-diethyl-2-oxo-6-phenyl-4-(2-(2,6,6-trimethylcyclohex-2-enyl)vinyl)cyclohex-3-enecarboxamide
• 英文别名: N,N-diethyl-2-oxo-6-phenyl-4-[(E)-2-(2,6,6-trimethylcyclohex-2-en-1-yl)ethenyl]cyclohex-3-ene-1-carboxamide
• 化学式: C₂₈H₃₇NO₂
• 分子量: 419.607
• InChiKey: OKSNFXKWXZKXMV-FOCLMDBBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-phenyl-5-(2,6,6-trimethylcyclohex-2-enyl)penta-1,4-dien-3-one 、 N,N-二乙基乙酰乙酰胺 在 sodium ethanolate 作用下， 以 乙醇 为溶剂， 反应 3.0h， 以75%的产率得到N,N-diethyl-2-oxo-6-phenyl-4-(2-(2,6,6-trimethylcyclohex-2-enyl)vinyl)cyclohex-3-enecarboxamide
  参考文献：
  名称：

  Cyclohexenones Through Regioselective Addition of 1,3-Dicarbonyl Compounds to Terpenoid-Like Bischalcones

  摘要：

  Terpenoid-like bischalcones (3 and 4) were synthesized from the reaction of - and -ionones and benzaldehydes in excellent yields. The Michael addition of 1,3-dicarbonyl compounds to bischalcones (3 and 4) resulted in the formation of cyclohexenones derivatives (10a-d and 14a, b) via regioselective addition of 1,3-dicarbonyls and then cyclization.

  DOI：

  10.1080/00397910902793877

文献信息

• Cyclohexenones Through Regioselective Addition of 1,3-Dicarbonyl Compounds to Terpenoid-Like Bischalcones
  作者：Esra Findik、Yakup Budak、Mustafa Ceylan

  DOI：10.1080/00397910902793877

  日期：2009.9.18

  Terpenoid-like bischalcones (3 and 4) were synthesized from the reaction of - and -ionones and benzaldehydes in excellent yields. The Michael addition of 1,3-dicarbonyl compounds to bischalcones (3 and 4) resulted in the formation of cyclohexenones derivatives (10a-d and 14a, b) via regioselective addition of 1,3-dicarbonyls and then cyclization.