(S)-(+)-ethyl-(2-hydroxy-1-propyl)thioether

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-(+)-ethyl-(2-hydroxy-1-propyl)thioether
• 英文别名: (2S)-1-(ethylsulfanyl)propan-2-ol；(2S)-1-ethylsulfanylpropan-2-ol
• 化学式: C₅H₁₂OS
• 分子量: 120.216
• InChiKey: GPZJYTNYOFOTAI-YFKPBYRVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (S)-(+)-2-羟丙基对甲苯磺酸盐 、 乙硫醇钠 以 N,N-二甲基甲酰胺 为溶剂， 以81%的产率得到(S)-(+)-ethyl-(2-hydroxy-1-propyl)thioether
  参考文献：
  名称：

  Novel bi- and tridentate phosphane and thioether ligands derived from chiral α-hydroxy acids

  摘要：

  Novel bi- and tridentate ligands with phosphane and thioether moieties have been prepared in enantiomerically pure form in good to excellent yields by substitution reactions with phosphorus and sulfur nucleophiles of easily available tosylates derived from natural chiral cx-hydroxy acids. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00103-2

文献信息

• Novel bi- and tridentate phosphane and thioether ligands derived from chiral α-hydroxy acids
  作者：Jens Christoffers、Ulrich Rößler

  DOI：10.1016/s0957-4166(99)00103-2

  日期：1999.3

  Novel bi- and tridentate ligands with phosphane and thioether moieties have been prepared in enantiomerically pure form in good to excellent yields by substitution reactions with phosphorus and sulfur nucleophiles of easily available tosylates derived from natural chiral cx-hydroxy acids. (C) 1999 Elsevier Science Ltd. All rights reserved.