(2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-6-[[(4aR,6S,7R,8R,8aS)-6-[(2R,3S,4R,5R,6S)-5-azido-6-[tert-butyl(dimethyl)silyl]oxy-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-7-hydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy]-5-azido-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-6-[[(4aR,6S,7R,8R,8aS)-6-[(2R,3S,4R,5R,6S)-5-azido-6-[tert-butyl(dimethyl)silyl]oxy-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-7-hydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy]-5-azido-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₁₀₅H₁₂₆N₆O₂₇Si
• 分子量: 1932.26
• InChiKey: SMWBFZZTQHQNLA-IGZPIQDTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.18
• 重原子数：
  139
• 可旋转键数：
  43
• 环数：
  16.0
• sp3杂化的碳原子比例：
  0.49
• 拓扑面积：
  333
• 氢给体数：
  5
• 氢受体数：
  31

反应信息

• 作为反应物：
  描述：

  苯甲醛二甲缩醛 、 (2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-6-[[(4aR,6S,7R,8R,8aS)-6-[(2R,3S,4R,5R,6S)-5-azido-6-[tert-butyl(dimethyl)silyl]oxy-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-7-hydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy]-5-azido-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 在 对甲苯磺酸 作用下， 以 乙腈 为溶剂， 反应 1.0h， 以86%的产率得到
  参考文献：
  名称：

  Toepfer, Alexander; Kinzy, Willy; Schmidt, Richard R., Liebigs Annalen der Chemie, 1994, # 5, p. 449 - 464

  摘要：

  DOI：
• 作为产物：
  描述：

  在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以100%的产率得到(2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-6-[[(4aR,6S,7R,8R,8aS)-6-[(2R,3S,4R,5R,6S)-5-azido-6-[tert-butyl(dimethyl)silyl]oxy-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-7-hydroxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy]-5-azido-4-[(2S,3S,4R,5R,6S)-6-methyl-3,4,5-tris(phenylmethoxy)oxan-2-yl]oxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  参考文献：
  名称：

  Toepfer, Alexander; Kinzy, Willy; Schmidt, Richard R., Liebigs Annalen der Chemie, 1994, # 5, p. 449 - 464

  摘要：

  DOI：

文献信息

• Toepfer, Alexander; Kinzy, Willy; Schmidt, Richard R., Liebigs Annalen der Chemie, 1994, # 5, p. 449 - 464
  作者：Toepfer, Alexander、Kinzy, Willy、Schmidt, Richard R.

  DOI：——

  日期：——