The invention relates to compounds of formula (I) for treating for example sexual dysfunction, wherein R
1
is optionally substituted C
1-6
alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, hydrogen, C
1-6
alkoxy, —NR
2
R
3
or —NR
4
SO
2
R
5
; X is the linkage —(CH
2
)
n
— or —(CH
2
)
q
—O— (wherein Y is attached to the oxygen); wherein one or more hydrogen atoms in linkage X may be replaced independently by C
1-4
alkoxy; hydroxy; hydroxy(C
1-3
alkyl); C
3-7
cycloalkyl; carbocyclyl; heterocyclyl; or by C
1-4
alkyl optionally substituted by one or more fluoro or phenyl groups; n is
3, 4, 5, 6
or
7;
and q is
2, 3, 4, 5
or
6;
and Y is phenyl or pyridyl, each of which may be substituted; or two R
8
groups on adjacent carbon atoms together with the interconnecting carbon atoms may form a fused optionally substituted
5
- or
6
-membered carbocyclic or heterocyclyic ring.
1
该发明涉及用于治疗性功能障碍的化合物(I)的公式，其中R1是可选择取代的C1-6烷基，可选择取代的碳环烷基，可选择取代的杂环烷基，氢，C1-6烷氧基，—NR2R3或—NR4SO2R5；X是连接基—(
CH2)n—或—( )q—O—（其中Y连接到氧原子）；其中连接基X中的一个或多个氢原子可以独立地被C1-4烷氧基，羟基，羟基(C1-3烷基)，C3-7环烷基，碳环烷基，杂环烷基或可选择取代的一个或多个
氟或苯基的C1-4烷基替代；n为3、4、5、6或7；q为2、3、4、5或6；Y为苯基或
吡啶基，每个基都可以被取代；或相邻碳原子上的两个R8基连同相互连接的碳原子可以形成一个可选择取代的5-或6-成员碳环或杂环环。
