2,3-difluoro-4-ethoxy-[trans-4-(2,3-difluorophenoxymethyl)cyclohexyl]benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,3-difluoro-4-ethoxy-[trans-4-(2,3-difluorophenoxymethyl)cyclohexyl]benzene
• 英文别名: 1-[4-[(2,3-difluorophenoxy)methyl]cyclohexyl]-4-ethoxy-2,3-difluorobenzene
• 化学式: C₂₁H₂₂F₄O₂
• 分子量: 382.398
• InChiKey: OHVSMQUJVQLLKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,3-difluoro-4-ethoxy-[trans-4-(2,3-difluorophenoxymethyl)cyclohexyl]benzene 在 仲丁基锂 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 正己烷 、 环己烷 、 甲苯 为溶剂， 反应 12.0h， 生成 2-(4-((trans-4-(4-ethoxy-2,3-difluorophenyl)cyclohexyl)methoxy)-2,3-difluorophenyl)-5-pentyl-1,3-dioxane
  参考文献：
  名称：

  TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT

  摘要：

  公开号：

  EP2305627B1
• 作为产物：
  描述：

  4-(4-ethoxy-2,3-difluorophenyl)-cyclohexanecarboxaldehyde 在 吡啶 、 potassium phosphate 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 12.0h， 生成 2,3-difluoro-4-ethoxy-[trans-4-(2,3-difluorophenoxymethyl)cyclohexyl]benzene
  参考文献：
  名称：

  TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT

  摘要：

  公开号：

  EP2305627B1

文献信息

• FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Kobayashi Masahide

  公开号：US20110090450A1

  公开（公告）日：2011-04-21

  The invention provides a liquid crystal compound which has stability to heat, light and so forth, a nematic phase in a wide temperature range, a small viscosity, a large optical anisotropy, and a suitable elastic constant K 33 , and further has a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds. Moreover, the invention provides a liquid crystal composition comprising this liquid crystal compound and a liquid crystal display device containing this liquid crystal composition. A liquid crystal compound represented by formula (a): for example, R 1 and R 2 are alkyl having 1 to 10 carbons, alkenyl having 2 to 10 carbons or alkoxy having 1 to 9 carbons; ring A 1 and ring A 2 are 1,4-phenylene or trans-1,4-cyclohexylene; L 1 and L 2 are hydrogen or fluorine, and at least one of L 1 and L 2 is fluorine; and Z 1 and Z 2 are a single bond, —(CH 2 ) 2 —, —CH═CH—, —CH 2 O— or —OCH 2 —.

  本发明提供一种液晶化合物，具有耐热、耐光等稳定性，在广泛的温度范围内具有向列相，粘度小，光学各向异性大，适当的弹性常数K33，进一步具有适当且负的介电各向异性，与其他液晶化合物具有良好的相容性。此外，本发明还提供了包含该液晶化合物的液晶组合物和包含该液晶组合物的液晶显示装置。一种由公式（a）表示的液晶化合物：例如，R1和R2是具有1至10个碳原子的烷基，具有2至10个碳原子的烯基或具有1至9个碳原子的烷氧基；环A1和环A2是1,4-苯撑基或反-1,4-环己撑基；L1和L2是氢或氟，且至少有一个是氟；Z1和Z2是单键，-(CH2)2-，-CH═CH-，-CH2O-或-OCH2-。
• THREE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Kobayashi Masahide

  公开号：US20110037024A1

  公开（公告）日：2011-02-17

  The invention provides a liquid crystal compound represented by the following formula having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a large optical anisotropy and a suitable elastic constant K 33 (K 33 : bend elastic constant), and further having a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds, and provides a liquid crystal composition including the compound, wherein R 1 and R 2 are hydrogen, alkyl or the like, ring A 1 is trans-1,4-cyclohexylene, 1,4-phenylene or the like, L 1 to L 4 are hydrogen or fluorine, and at least three of them are fluorine; when the ring A 1 is trans-1,4-cyclohexylene or the like, Z 1 is a single bond, —(CH 2 ) 2 — or the like, when ring A 1 is 1,4-phenylene, Z 1 is —(CH 2 ) 2 — or the like.

  该发明提供了一种液晶化合物，其由以下公式表示，具有耐热、耐光等稳定性，具有向列相的宽温度范围、小粘度、大光学各向异性和适当的弹性常数K33（K33：弯曲弹性常数），并且具有适当的负电介质各向异性和与其他液晶化合物良好的相容性，并提供了包括该化合物的液晶组合物，其中R1和R2是氢、烷基或类似物，环A1是反式-1,4-环己基、1,4-苯基或类似物，L1到L4是氢或氟，其中至少三个是氟；当环A1为反式-1,4-环己基或类似物时，Z1是单键，-(CH2)2-或类似物，当环A1为1,4-苯基时，Z1是-(CH2)2-或类似物。
• TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Chisso Corporation

  公开号：EP2266941A1

  公开（公告）日：2010-12-29

  The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a large optical anisotropy and a suitable elastic constant K33 (K33: bend elastic constant), and further having a suitable and negative dielectric anisotropy and an excellent compatibility with other liquid crystal compounds, and provides a liquid crystal composition having a small viscosity, a large optical anisotropy, a suitable elastic constant K33, a suitable and negative dielectric anisotropy, and further having a low threshold voltage, a high maximum temperature of a nematic phase and a low minimum temperature of the nematic phase. In a specific structure having phenylene in which hydrogen on the benzene ring is replaced by fluorine, a three-ring liquid crystal compound having fluorine at a lateral position, and a liquid crystal composition containing the compound are prepared.

  本发明提供了一种液晶化合物，它具有对热、光等的稳定性，向列相的温度范围宽，粘度小，光学各向异性大，弹性常数K33（K33：弯曲弹性常数），并进一步具有合适的负介电各向异性以及与其他液晶化合物的良好兼容性，从而提供了一种具有小粘度、大光学各向异性、合适的弹性常数 K33、合适的负介电各向异性，并进一步具有低阈值电压、向列相的最高温度高和向列相的最低温度低的液晶组合物。在具有苯环上的氢被氟取代的苯的特定结构中，制备了在侧向位置具有氟的三环液晶化合物和含有该化合物的液晶组合物。
• US8216489B2
  申请人：——

  公开号：US8216489B2

  公开（公告）日：2012-07-10
• US8394294B2
  申请人：——

  公开号：US8394294B2

  公开（公告）日：2013-03-12