5-[5-(2,2-dimethylcyclopropyl)-3-methylpent-2-enyloxy]-2-methylpyridine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-[5-(2,2-dimethylcyclopropyl)-3-methylpent-2-enyloxy]-2-methylpyridine
• 英文别名: 5-[(E)-5-(2,2-dimethylcyclopropyl)-3-methylpent-2-enoxy]-2-methylpyridine
• 化学式: C₁₇H₂₅NO
• 分子量: 259.392
• InChiKey: MZONPSIVJIGGAI-UKTHLTGXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-(2,2-Dichlor-3,3-dimethylcyclopropyl)-3-methyl-1-penten-3-ol 在 氨 、 氢溴酸 、 sodium methylate 、 sodium 作用下， 以 甲醇 、 乙醚 为溶剂， 反应 18.75h， 生成 5-[5-(2,2-dimethylcyclopropyl)-3-methylpent-2-enyloxy]-2-methylpyridine
  参考文献：
  名称：

  昆虫幼激素类似物及其对海虱的生物学活性。

  摘要：

  对昆虫黄粉虫进行测试时，已显示出许多显示少年激素活性的合成化合物可抑制海虱物种鲑鱼麻风病的发展。对分离的无节幼体幼鱼和活的大西洋鲑鱼（Salmo salar）均进行了测试。

  DOI：

  10.1021/jf049259h

文献信息

• CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS
  申请人：Bioparken AS

  公开号：EP1204413A2

  公开（公告）日：2002-05-15
• NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS
  申请人：Bioparken AS

  公开号：EP1204320A2

  公开（公告）日：2002-05-15
• [EN] NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS<br/>[FR] NOUVEAUX ANALOGUES DE L'HORMONE JUVENILE UTILISES COMME AGENTS ANTI-SALISSURES
  申请人：FORSKNINGSPARKEN I AAS AS

  公开号：WO2001006853A2

  公开（公告）日：2001-02-01

  The use of juvenile hormone analogues (juvenoids, juvenile hormone-like compounds, juvenile hormone mimics) compounds as antifouling agents in e.g. paint compositions for ships and immersed structures including oil drilling rigs and fish nets and novel juvenile hormone compounds. The compounds are active against barnacles including species of Cirripedia such as Balanus species and prevent crucial steps in the process of barnacle fouling on solid surfaces such as the settlement, attachment and/or metamorphosis of barnacle cyprid larvae.
• [EN] CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS<br/>[FR] LUTTE CONTRE L'INFESTATION D'ANIMAUX AQUATIQUES PAR DES ECTOPARASITES DE CRUSTACES
  申请人：FORSKNINGSPARKEN I AAS AS

  公开号：WO2001007047A2

  公开（公告）日：2001-02-01

  Use of juvenile hormone analogue compounds (juvenoids, juvenile hormone mimics) for the control of crustacean infestation in fish, such as sea lice infestation, in particular infestations with lepeophtheirus salmonis and caligus elongatus in wild and farmed fish of the family salmonidae including Atlantic salmon and trout. The compounds are preferably administered via the feed or as bath treatment medication.
• Insect Juvenile Hormone Analogues and Their Biological Activity on Sea Lice (<i>Lepeophtheirus salmonis</i>)
  作者：Lars Skattebøl、Yngve Stenstrøm、Christian Syvertsen

  DOI：10.1021/jf049259h

  日期：2004.11.1

  A number of synthetic compounds that exhibit juvenile hormone activity when tested on the insect species Tenebrio molitor have been shown to inhibit the development of the sea lice species Lepeophtheirus salmonis. The testing was carried out on both isolated nauplius larvae and live Atlantic salmon (Salmo salar).

  对昆虫黄粉虫进行测试时，已显示出许多显示少年激素活性的合成化合物可抑制海虱物种鲑鱼麻风病的发展。对分离的无节幼体幼鱼和活的大西洋鲑鱼（Salmo salar）均进行了测试。