1,7-吖啶二胺 | 22593-73-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 1,7-吖啶二胺
• 英文名称: 2,8-Diaminoacridin
• 英文别名: acridine-1,7-diyldiamine；Acridin-1,7-diyldiamin；2,8-Diaminoacridine；1,7-Acridinediamine；acridine-1,7-diamine
• CAS: 22593-73-3
• 化学式: C₁₃H₁₁N₃
• 分子量: 209.25
• InChiKey: PAOHOFLZJDJJLR-UHFFFAOYSA-N

物化性质

• 熔点：
  126 °C
• 沸点：
  500.1±25.0 °C(Predicted)
• 密度：
  1.346±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.9
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  1,7-diamino-10H-acridin-9-one 在 sodium amalgam 、 乙醇 作用下， 生成 1,7-吖啶二胺
  参考文献：
  名称：

  Goldberg; Kelly, Journal of the Chemical Society, <1946> 102, 108, 110

  摘要：

  DOI：

文献信息

• Compositions of matter having bioactive properties
  申请人：Schmitz, Robert A.

  公开号：EP1288238A1

  公开（公告）日：2003-03-05

  Particles of coordinated complex comprising a basic, hydrous polymer and a capacitance adding compound, as well as methods for their production, are described. These complexes exhibit a high degree of bioactivity making them suitable for a broad range of applications through their incorporation into conventional vehicles benefiting from antimicrobial and similar properties.

  描述了由基础水合聚合物和电容添加化合物组成的协调复合物的颗粒，以及它们的生产方法。这些复合物表现出很高的生物活性，使它们适用于广泛的应用领域，通过将它们纳入传统载体中，从而受益于抗菌和类似性能。
• Method for determining the DNA repair capacity of a cell
  申请人：Pangaea Biotech, S.A.

  公开号：EP2123770A1

  公开（公告）日：2009-11-25

  The invention relates to methods for determining the inherited or acquired DNA repair capacity of a cell or cell population, and to the use of said method for determining the genetic susceptibility to cancer of a subject or for predicting the response of a subject suffering from cancer to a chemotherapy treatment directed to damaging the DNA. These methods involve the use of a polynucleotide encoding in its natural form a fluorescent protein (e.g. EGFP). Said polynucleotide has been previously contacted with a genotoxic agent (e.g. UV), rendering said polynucleotide unable to express a functional fluorescent protein. Host repair system capacity will be assessed by fluorescence.

  本发明涉及确定细胞或细胞群遗传或获得的 DNA 修复能力的方法，以及使用所述方法确定受试者对癌症的遗传易感性或预测癌症患者对旨在破坏 DNA 的化疗的反应。 这些方法涉及使用以天然形式编码荧光蛋白（如 EGFP）的多核苷酸。所述多核苷酸曾与一种基因毒性物质（如紫外线）接触，从而使所述多核苷酸无法表达功能性荧光蛋白。宿主修复系统的能力将通过荧光来评估。
• Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto
  申请人：EMORY UNIVERSITY

  公开号：US10434220B2

  公开（公告）日：2019-10-08

  The disclosure relates to compounds and compositions for bone formation, fracture treatment, bone grafting, bone fusion, cartilage maintenance and repair, and methods related thereto. In certain embodiments, the disclosure relates to compositions comprising one or more compound(s) disclosed herein derivatives, or salt thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement. In certain embodiments, compounds disclosed herein are useful for managing obesity and diabetes or other metabolic syndromes by modulation of brown fat.

  本公开涉及用于骨形成、骨折治疗、骨移植、骨融合、软骨维护和修复的化合物和组合物，以及与之相关的方法。在某些实施方案中，本公开涉及包含一种或多种本文公开的化合物衍生物或其盐的组合物，用于骨生长过程。在一个典型的实施方案中，骨移植组合物被植入受试者所需骨生长或增强的部位。在某些实施方案中，本文公开的化合物可通过调节棕色脂肪来控制肥胖和糖尿病或其他代谢综合征。
• Goldberg; Kelly, Journal of the Chemical Society, <1946> 102, 108, 110
  作者：Goldberg、Kelly

  DOI：——

  日期：——
• FUEL CELL
  申请人：Tokita Yuichi

  公开号：US20110143223A1

  公开（公告）日：2011-06-16

  A fuel cell is provided. The fuel cell includes at least one of a plant essential oil and a plant essential oil ingredient in an effective amount so as to function as a biological repellent.