暂无 | 69045-85-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 暂无
• 英文名称: 2-(4-hydroxyphenoxy)-5-trifluoromethylpyridine
• 英文别名: 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)phenol；4-(5-(trifluoromethyl)pyridin-2-yloxy)phenol；4-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenol；p-[(5-trifluoromethyl-pyridin-2-yl)oxy]-phenol；2-p-hydroxyphenoxy-5-trifluoromethylpyridine；4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol；4-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}phenol；4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenol
• CAS: 69045-85-8
• 化学式: C₁₂H₈F₃NO₂
• mdl: MFCD00102509
• 分子量: 255.196
• InChiKey: LXXDBPUREVMTMI-UHFFFAOYSA-N

物化性质

• 熔点：
  89 - 91°C
• 沸点：
  341.9±42.0 °C(Predicted)
• 密度：
  1.378±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于氯仿（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.083
• 拓扑面积：
  42.4
• 氢给体数：
  1
• 氢受体数：
  6

安全信息

• 海关编码：
  2933399090

反应信息

• 作为反应物：
  描述：

  2-(4-hydroxyphenoxy)-5-trifluoromethylpyridine 以 乙醇 为溶剂， 生成 Sodium Salt of 4-(5-Trifluoromethylpyridyl-2-oxy)phenol
  参考文献：
  名称：

  2-Phenoxy-5-trifluoromethylpyridine compounds and process for

  摘要：

  由以下通用式（I）表示的2-苯氧基-5-三氟甲基吡啶化合物：其中X代表氢原子或氯原子，R代表氢原子或阳离子，以及其制备方法。

  公开号：

  US04152328A1
• 作为产物：
  描述：

  2-(4-methoxyphenoxy)-5-trifluoromethylpyridine 在 氢溴酸 、 四正丁基溴化膦 作用下， 反应 6.0h， 生成 2-(4-hydroxyphenoxy)-5-trifluoromethylpyridine
  参考文献：
  名称：

  48% Hbr/四正丁基溴化鏻选择性裂解芳氧基芳基甲基醚的芳基甲基醚部分

  摘要：

  摘要 在四正丁基溴化鏻的存在下，使用 48% HBr 选择性地裂解含有芳基芳基醚部分和芳基甲基醚部分的分子中的芳基甲基醚部分，以优异的收率得到所需的取代苯酚。

  DOI：

  10.1080/00397919308012606

文献信息

• Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
  申请人：——

  公开号：US20030166644A1

  公开（公告）日：2003-09-04

  Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.

  使用化合物抑制激素敏感性脂肪酶，包括这些化合物的药物组合物，使用这些化合物和组合物的治疗方法，以及新化合物。目前的化合物是激素敏感性脂肪酶的抑制剂，可能在治疗和/或预防需要降低激素敏感性脂肪酶活性的医学疾病中有用。
• Herbicidal, optically active or racemic substituted propionic acid derivatives, herbicide compositions containing them and process for preparing same
  申请人：ALKALOIDA VEGYESZETI GYAR

  公开号：EP0426491A2

  公开（公告）日：1991-05-08

  The invention relates to novel, herbicidally active 2-[4-(5-trifluoromethyl-2-pyridyloxy)phenoxy]propionic acid derivatives of the general formula (I), wherein A depends on the value of n in such a way that: 1) when n is 0 (zero), A stands for an -NR1R2 substituted amino group, wherein a) R1 stands for hydrogen; R2 means a C1-4alkyl, C2-4alkenyl, C4-7cycloalkyl, heteroaryl-C1-4alkyl group or a -B-NR3R4 group, where B stands for a straight or branched chain C2-4 alkylene group; R3 and R4 are C1-4alkyl groups or R3 and R4 together form an alicyclic group containing 2 to 6 methylene groups and the cycle, when consisting of 6 members, may contain an oxygen or an additional substi tuted or unsubstituted nitrogen in 4-position related to the nitrogen; b) R1 and R2 are different from hydrogen and represent a C1-4alkyl or C2-4alkylene group; or R1 and R2 together form an alicyclic group containing 2-6 methylene groups and the ring, when consisting of 6 members, may contain an oxygen in 4-position related to the nitrogen; 2) when n is other than 0 (zero) (n is 1 or 2), A stands for: a) an -NR5R6 disubstituted amino group, wherein R5 and R6 represent a C1-4alkyl or C2-4alkenyl group; or R5 and R6 together form an alicyclic group containing 2 to 6 methylene groups, and the ring, when consisting of 6 members, may contain an oxygen or an additional substituted or unsubstituted nitrogen in 4-position related to the nitrogen, the alicyclic ring optionally being substituted by one or more methyl group(s); b) or an -O-N = C(CH3)2 group. The invention also relates to herbicide compositions containing the compounds of the general formula (I) as active ingredients as well as to a process for the preparation of these compounds and compositions. The compounds of the general formula (I) selectively kill the monocotyledonous weeds and thus, they can be used for killing monocotyledonous weeds in dicotyledonous cultures.

  该发明涉及一种新颖的除草活性2-[4-(5-三氟甲基-2-吡啶氧基)苯氧基]丙酸衍生物，其一般式为（I），其中A取决于n的值，方式如下：1）当n为0（零）时，A代表一个-NR1R2取代的氨基团，其中a) R1代表氢；R2表示C1-4烷基，C2-4烯基，C4-7环烷基，杂环芳基-C1-4烷基基团或-B-NR3R4基团，其中B代表直链或支链C2-4烷基基团；R3和R4是C1-4烷基基团或R3和R4一起形成含有2至6个亚甲基基团的脂环基团，当环由6个成员组成时，可能在氮原子的4-位附近含有氧或一个额外取代或未取代的氮原子；b) R1和R2不同于氢，并表示C1-4烷基或C2-4烯基基团；或R1和R2一起形成含有2-6个亚甲基基团的脂环基团，当环由6个成员组成时，可能在氮原子的4-位附近含有氧；2）当n不为0（零）时（n为1或2），A代表：a) 一个-NR5R6二取代氨基团，其中R5和R6代表C1-4烷基或C2-4烯基基团；或R5和R6一起形成含有2至6个亚甲基基团的脂环基团，当环由6个成员组成时，可能在氮原子的4-位附近含有氧或一个额外取代或未取代的氮原子，该脂环环可选择性地被一个或多个甲基基团取代；b) 或一个-O-N = C(CH3)2基团。该发明还涉及含有一般式（I）化合物的除草剂组合物作为活性成分，以及制备这些化合物和组合物的过程。一般式（I）化合物选择性杀死单子叶杂草，因此可以用于在双子叶作物中除去单子叶杂草。
• [EN] AGRICULTURAL CHEMICALS<br/>[FR] PRODUITS CHIMIQUES AGRICOLES
  申请人：REDX PHARMA LTD

  公开号：WO2013136073A1

  公开（公告）日：2013-09-19

  The present invention relates to derivatives of compounds which are known to be of use in the field of agriculture. These derivatives are differentiated from the parent active compound by virtue of being redox derivatives of the active compound. This means that one or more of the functional groups in the active compound has been converted to another group in one or more changes one or more of which may be considered to represent a change of oxidation state relative to the groups in the original compound. We refer to these compounds generally as redox derivatives. The compounds are of use as insecticides, herbicides and insect repellents.

  本发明涉及与已知在农业领域中有用的化合物衍生物。这些衍生物通过成为活性化合物的氧化还原衍生物而与母体活性化合物区分开来。这意味着活性化合物中的一个或多个官能团已被转化为另一个官能团，其中一个或多个变化可能被认为代表相对于原始化合物中的官能团的氧化状态的变化。我们通称这些化合物为氧化还原衍生物。这些化合物可用作杀虫剂、除草剂和驱虫剂。
• AGRICULTURAL CHEMICALS
  申请人：Redx Pharma Ltd.

  公开号：US20150094474A1

  公开（公告）日：2015-04-02

  The present invention relates to derivatives of compounds which are known to be of use in the field of agriculture. These derivatives are differentiated from the parent active compound by virtue of being redox derivatives of the active compound. This means that one or more of the functional groups in the active compound has been converted to another group in one or more changes one or more of which may be considered to represent a change of oxidation state relative to the groups in the original compound. We refer to these compounds generally as redox derivatives. The compounds are of use as insecticides, herbicides and insect repellents.

  本发明涉及与农业领域中已知有用的化合物衍生物。这些衍生物通过成为活性化合物的氧化还原衍生物而与母体活性化合物区分开来。这意味着活性化合物中的一个或多个官能团已经转化为另一个官能团，其中一个或多个转变可能被认为代表相对于原始化合物中的官能团的氧化状态的变化。我们通常将这些化合物称为氧化还原衍生物。这些化合物可用作杀虫剂、除草剂和驱虫剂。
• 2-(Substituted phenoxy)propionic acid derivatives and their uses for
  申请人：Hokko Chemical Industry Co., Ltd.

  公开号：US04447259A1

  公开（公告）日：1984-05-08

  New 2-(substituted-phenoxy)propionic acid derivatives are provided, which have the structure of the general formula: ##STR1## and R.sub.2 is a hydrogen atom or a lower alkyl group. They have a high herbicidal activity to weeds, particularly graminaceous weeds, while they have little or no phytotoxicity to broad leaved crop plants and are therefore useful as selective herbicide.

  提供了新的2-(取代苯氧基)丙酸衍生物，其具有一般式的结构：##STR1##和R.sub.2是氢原子或较低的烷基基团。它们对杂草，特别是禾本科杂草具有很高的除草活性，同时对宽叶作物几乎没有植物毒性，因此可作为选择性除草剂。