1-(3,4-二羟基苯基)-4,4-二甲基-1-戊烯-3-酮 | 66596-39-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 中文名称: 1-(3,4-二羟基苯基)-4,4-二甲基-1-戊烯-3-酮
• 英文名称: 4-(tert-Butylcarbonylvinyl)pyrocatechol
• 英文别名: (E)-1-(3,4-dihydroxyphenyl)-4,4-dimethylpent-1-en-3-one
• CAS: 66596-39-2
• 化学式: C₁₃H₁₆O₃
• mdl: MFCD00870705
• 分子量: 220.26
• InChiKey: AESAELLIDNODSF-FNORWQNLSA-N

物化性质

• 沸点：
  394.0±32.0 °C(Predicted)
• 密度：
  1.156±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.307
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2914501900

文献信息

• Glycol esters of dicaffeoylquinic acid and uses thereof
  申请人：PLANT ADVANCED TECHNOLOGIES PAT

  公开号：US10426717B2

  公开（公告）日：2019-10-01

  Disclosed are glycol esters of dicaffeoylquinic acids, in particular dipropylene glycol esters of dicaffeoylquinic acids (DPG esters of DCQ) and propane-1.3-diol esters of dicaffeoylquinic acids of general formula: wherein R1 is a dipropylene glycol radical or a propane 1,3 diol radical, and any two of the radicals R2, R3, R4 and R5 are a caffeoyl group, the other two being a hydrogen atom. Also disclosed is a plant extract including same, the method for preparing same and a cosmetic composition including the compounds or extracts, intended for preventing or delaying the appearance of skin ageing effects.

  所公开的是二咖啡酰奎宁酸的乙二醇酯，特别是通式为二咖啡酰奎宁酸的二丙二醇酯（DCQ 的 DPG 酯）和二咖啡酰奎宁酸的丙烷-1.3-二醇酯： 其中 R1 是二丙二醇基或丙烷-1,3-二醇基，R2、R3、R4 和 R5 中的任意两个是咖啡酰基，另外两个是氢原子。还公开了包括上述化合物或提取物的植物提取物、其制备方法和化妆品组合物，旨在防止或延缓皮肤老化效应的出现。
• Menaquinol compositions and methods of treatment
  申请人：Epizon Pharma, Inc.

  公开号：US10822295B2

  公开（公告）日：2020-11-03

  The present application discloses methods for the efficient preparation of high purity compounds of the Formula I, and their methods of use. Also disclosed herein are pharmaceutical compositions comprising a therapeutically effective amount of a menaquinol compound as disclosed above, or a mixture thereof, and a pharmaceutically acceptable excipient, wherein the composition is effective for the treatment of a condition associated with vitamin K selected from for the treatment of osteoporosis and arteriosclerosis.

  本申请公开了高效制备高纯度式 I 化合物的方法及其使用方法。 本文还公开了药物组合物，该组合物包含治疗有效量的如上所述的孟喹醇化合物或其混合物，以及药学上可接受的赋形剂，其中该组合物对治疗与维生素 K 有关的病症有效，这些病症选自骨质疏松症和动脉硬化。
• COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE
  申请人：Chromocell Corporation

  公开号：US20170188606A1

  公开（公告）日：2017-07-06

  The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of sugar in a food product, and methods of reducing bitter taste in a food product.
• GLYCOL ESTERS OF DICAFFEOYLQUINIC ACID AND USES THEREOF
  申请人：PLANT ADVANCED TECHNOLOGIES PAT

  公开号：US20190038533A1

  公开（公告）日：2019-02-07

  Disclosed are glycol esters of dicaffeoylquinic acids, in particular dipropylene glycol esters of dicaffeoylquinic acids (DPG esters of DCQ) and propane-1.3-diol esters of dicaffeoylquinic acids of general formula: wherein R 1 is a dipropylene glycol radical or a propane 1,3 diol radical, and any two of the radicals R 2 , R 3 , R 4 and R 5 are a caffeoyl group, the other two being a hydrogen atom. Also disclosed is a plant extract including same, the method for preparing same and a cosmetic composition including the compounds or extracts, intended for preventing or delaying the appearance of skin ageing effects.
• Menaquinol Compositions and Methods of Treatment
  申请人：Epizon Pharma, Inc.

  公开号：US20210009494A1

  公开（公告）日：2021-01-14

  The present application discloses methods for the efficient preparation of high purity compounds of the Formula I, and their methods of use.