申请人:Schroeder Bjorn Christian
公开号:US20090307791A1
公开(公告)日:2009-12-10
The present invention provides a cloned, isolated calcium-activated chloride channel, and a polynucleotide comprising a nucleotide sequence encoding the channel. The present invention further provides a genetically modified cell comprising a subject polynucleotide, and use of the cells to identify agents that modulate calcium-activated chloride channel activity. The present invention further provides genetically modified cells and non-human animals that do not express a subject calcium-activated chloride channel.