2,4-二氯-2-丁烯醛 | 26394-31-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2,4-二氯-2-丁烯醛
• 英文名称: 2,4-dichloro-but-2-enal
• 英文别名: 2,4-dichloro-crotonaldehyde；2,4-Dichlor-crotonaldehyd；2.4-Dichlor-buten-(2)-al-(1)；α.γ-Dichlor-crotonaldehyd；2,4-dichloro-2-butenal；2,4-dichlorobut-2-enal
• CAS: 26394-31-0
• 化学式: C₄H₄Cl₂O
• mdl: MFCD19232349
• 分子量: 138.981
• InChiKey: FSPXZKAEHGXEHN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2913000090

反应信息

• 作为反应物：
  描述：

  2,4-二氯-2-丁烯醛 在 溴 作用下， 生成 2,3-dibromo-2,4-dichloro-butyraldehyde
  参考文献：
  名称：

  Natterer, Monatshefte fur Chemie, 1883, vol. 4, p. 551

  摘要：

  DOI：
• 作为产物：
  描述：

  乙烯基乙炔 生成 2,4-二氯-2-丁烯醛
  参考文献：
  名称：

  Radical Addition of tert-Butyl Hypochlorite to Conjugated Enynes

  摘要：

  DOI：

  10.1021/jo00837a706

文献信息

• Method for the production of 3-phenylpyrrole derivatives
  申请人：NIPPON SODA CO., LTD.

  公开号：EP0092890A1

  公开（公告）日：1983-11-02

  A method for the production of 3-phenylpyrrole derivatives having the general formula wherein X is halogen, nitro or haloalkyl having 1 to 3 carbon atoms; n is 0, 1 or 2; and Z is hydrogen or halogen; characterized by reacting a compound having the general formula wherein X and n are as previously defined; and Y is hydrogen or halogen; with ammonia or aqueous ammonia in an organic solvent. A compound having the general formula (I) is useful as fungicide or intermediate thereof.

  一种生产具有通式的 3-苯基吡咯衍生物的方法 其中 X 为卤素、硝基或具有 1 至 3 个碳原子的卤代烷基； n 是 0、1 或 2；以及 Z 是氢或卤素；其特征是使通式为 其中 X 和 n 如前定义；以及 Y 是氢或卤素；与氨或有机溶剂中的氨水反应。 具有通式(I)的化合物可用作杀真菌剂或其中间体。
• PROCESS FOR PREPARING 3-CHLORO-1-FORMYL-4-PHENYL-PYRROLES
  申请人：NIPPON SODA CO., LTD.

  公开号：EP0134245A1

  公开（公告）日：1985-03-20

  A novel process for preparing 3-chloro-1-formyl-4-phenylpyrroles represented by the following formula (I) useful as agricultural and horticultural germicides, using 3-phenyl-2,2,4-trichlorobutanols represented by the formula (IV) as starting materials according to the following reaction wherein X represents the same or different substituent(s) selected from the group consisting of halogen, nitro, and trifluoromethyl groups, and n represents 0,1 or 2. This process enables to greatly shorten the preparation steps and improve the yield by employing novel pyrroline derivatives represented by the general formula (III).

  一种制备下式(I)所代表的 3-氯-1-甲酰基-4-苯基吡咯的新工艺，该工艺使用下式(IV)所代表的 3-苯基-2,2,4-三氯丁醇作为起始原料，按照以下反应制备，其中 X 代表相同或不同的取代基，这些取代基选自由卤素、硝基和三氟甲基组成的组，n 代表 0、1 或 2。 通过使用通式 (III) 所代表的新型吡咯啉衍生物，该工艺可大大缩短制备步骤并提高产率。
• Lespieau, Bulletin de la Societe Chimique de France, 1928, vol. <4>43, p. 206
  作者：Lespieau

  DOI：——

  日期：——
• The search for d-glucose derivatives suitable for the study of natural hydrogen isotope fractionation
  作者：J.Michael Williams、Hélène Jegou、Virginie Langlois、Ben-Li Zhang、Maryvonne L. Martin

  DOI：10.1016/0008-6215(93)80059-n

  日期：1993.7

  In order to apply Site-specific Natural Isotope Fractionation (SNIF) to chemical, biochemical, and environmental studies Of D-glucose, there is a need for readily prepared compounds which give H-2 NMR spectra with all or most signals resolved. Changing substituents at C-1 and/or C-6 of alpha-D-glucopyranose pentaacetate improved the dispersion of deuterium signals, the best results being achieved with 1,2,3,4-tetra-O-acetyl-6-deoxy-6-thiocyanato-alpha-D-glucopyranose, for which only the H-2-2 and 2 H-4 signals were not resolved, and with 2,3,4-tri-O-acetyl-6-bromo-6-deoxy-alpha-D-glucopyranosyl bromide, for which only the H-2-6a and H-2-6b signals were not resolved. Periodate oxidation of methyl 4,6-O-benzylidene-alpha-D-glucopyranoside and 4,6-dichloro-4,6-dideoxy-D-galactose was also examined as a possible source of useful compounds. Products obtained from the benzylideneglucoside gave inadequate resolution and broad deuterium signals. The oxidation of 4,6-dichloro-4,6-dideoxy-D-galactose was not straightforward. The a anomer was oxidised more rapidly than the beta anomer. The oxidation product, 2,4-dichloro-2,4-dideoxy-3-O-formyl-D-threose, was too labile to be isolated pure and its hydrolysis to 2,4-dichloro-2,4-dideoxy-D-threose was accompanied by a slow elimination to form 2,4-dichlorobut-2-enal.
• Natterer, Monatshefte fur Chemie, 1884, vol. 5, p. 579
  作者：Natterer

  DOI：——

  日期：——