N.N-Bistrimethylsilyl-p-trimethylsiloxyanilin | 31935-76-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N.N-Bistrimethylsilyl-p-trimethylsiloxyanilin
• 英文别名: N.N.O-Tristrimethylsilyl-p-aminophenol；N,N-bis(trimethylsilyl)-4-trimethylsilyloxyaniline
• CAS: 31935-76-9
• 化学式: C₁₅H₃₁NOSi₃
• 分子量: 325.674
• InChiKey: OAMUQXFOWYWABU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.38
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N.N-Bistrimethylsilyl-p-trimethylsiloxyanilin 、 五氯化铌 、 乙腈 以 乙腈 为溶剂， 以87%的产率得到
  参考文献：
  名称：

  A study of ortho- and para-siloxyanilines for the synthesis of mono-, bi-, and tetra-nuclear early transition metal–imido complexes

  摘要：

  The siloxyanilines o-Me(3)SiOC(6)H(4)NH(2) (1) and p-RMe(2)SiOC(6)H(4)NH(2) (R = H (2); R = Me (3)), and their N-silylated derivatives p-Me(3)SiOC(6)H(4)NHSiMe(3) (4) and p-Me(3)SiOC(6)H(4)N(SiMe(3))(2) (5) have been prepared from ortho- or para-aminophenol and used in the synthesis of imido complexes. Thus, binuclear [{Ti(eta (5)-C(5)H(5))Cl} {mu -NC(6)H(4)(p-OSiMe(3))}](2) (6) and mononuclear [TiCl(2){NC(6)H(4)(p-OSiMe(3))}(py)(3)] (7) imido complexes have been obtained from the reaction of 3 and [Ti(eta (5)-C(5)H(5))Cl(3)] or [TiCl(2)(N'Bu)(py)(3)], respectively. In contrast, the reaction of 1 with TiCl(4) and 'Bupy affords the titanocycle [TiCl(2){OC(6)H(4)(o-NH)-N,O}('Bupy)(2)] (8). Compound 5 has also been used to prepare the niobium imide complex [NbCl(3){NC(6)H(4)(p-OSiMe(3))}(MeCN)(2)] (9), by its reaction with NbCl(5) in CH(3)CN. These findings have been applied to the synthesis of polynuclear systems. Thus, chlorocarbosilane Si[CH(2)CH(2)CH(2)Si(Me)(2)Cl], (CS-Cl) has been functionalized with the ortho- and para-aminophenoxy groups to give 10 and 11, respectively. The use of 11 has allowed the formation of the tetranuclear compound 12. Attempts to synthesize terminal imido titanium complexes from 10 and TiCl(4) in the presence of 'Bupy and Et(3)N, give complex 8 and carbosilane CS-Cl. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00391-0
• 作为产物：
  描述：

  三甲基氯硅烷 、 对氨基苯酚 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 4.0h， 以88%的产率得到N.N-Bistrimethylsilyl-p-trimethylsiloxyanilin
  参考文献：
  名称：

  A study of ortho- and para-siloxyanilines for the synthesis of mono-, bi-, and tetra-nuclear early transition metal–imido complexes

  摘要：

  The siloxyanilines o-Me(3)SiOC(6)H(4)NH(2) (1) and p-RMe(2)SiOC(6)H(4)NH(2) (R = H (2); R = Me (3)), and their N-silylated derivatives p-Me(3)SiOC(6)H(4)NHSiMe(3) (4) and p-Me(3)SiOC(6)H(4)N(SiMe(3))(2) (5) have been prepared from ortho- or para-aminophenol and used in the synthesis of imido complexes. Thus, binuclear [{Ti(eta (5)-C(5)H(5))Cl} {mu -NC(6)H(4)(p-OSiMe(3))}](2) (6) and mononuclear [TiCl(2){NC(6)H(4)(p-OSiMe(3))}(py)(3)] (7) imido complexes have been obtained from the reaction of 3 and [Ti(eta (5)-C(5)H(5))Cl(3)] or [TiCl(2)(N'Bu)(py)(3)], respectively. In contrast, the reaction of 1 with TiCl(4) and 'Bupy affords the titanocycle [TiCl(2){OC(6)H(4)(o-NH)-N,O}('Bupy)(2)] (8). Compound 5 has also been used to prepare the niobium imide complex [NbCl(3){NC(6)H(4)(p-OSiMe(3))}(MeCN)(2)] (9), by its reaction with NbCl(5) in CH(3)CN. These findings have been applied to the synthesis of polynuclear systems. Thus, chlorocarbosilane Si[CH(2)CH(2)CH(2)Si(Me)(2)Cl], (CS-Cl) has been functionalized with the ortho- and para-aminophenoxy groups to give 10 and 11, respectively. The use of 11 has allowed the formation of the tetranuclear compound 12. Attempts to synthesize terminal imido titanium complexes from 10 and TiCl(4) in the presence of 'Bupy and Et(3)N, give complex 8 and carbosilane CS-Cl. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00391-0

文献信息

• Synthesis of (η6-arene)(η5-cyclopentadienyl) iron (II) complexes with heteroatom and carbonyl substituents. Part I: Oxygen and carbonyl substituents
  作者：R.M.G. Roberts

  DOI：10.1016/j.jorganchem.2005.12.070

  日期：2006.6

  used to introduce oxygen substituents into (η-arene)(η-cyclopentadienyl) iron (II) complexes. Photochemical ligand exchange led to the formation of the first recorded trioxygenated complex as well as mono- and di-oxygenated species. Using microwave techniques, reaction times for SNAr displacement reactions of halobenzene complexes by phenols were reduced from several hours to a few minutes. Phenols protected

  已使用一系列反应将氧取代基引入（η-芳烃）（η-环戊二烯基）铁（II）络合物中。光化学配体交换导致形成第一个记录的三加氧配合物以及单加氧和双加氧物质。使用微波技术，通过苯酚进行卤代苯配合物的S N Ar置换反应的反应时间从数小时减少至数分钟。苯酚受任一t保护使用常规的热配体交换反应，发现-丁基化或三甲基甲硅烷基化产生适量的相应酚配合物。没有这种保护，收率极低。上述方法导致二羟基苯配合物的第一实例的合成。还报告了一些其他合成方法。
• HAPKOH A. L.; BAXMUTOV V. I.; KARAPETYAN SH. A.; KALACHEV A. I.; VALETSKI+, IZV. AN CCCP. CEP. XIM., 1979, HO 5, 1090-1093
  作者：HAPKOH A. L.、 BAXMUTOV V. I.、 KARAPETYAN SH. A.、 KALACHEV A. I.、 VALETSKI+

  DOI：——

  日期：——
• A study of ortho- and para-siloxyanilines for the synthesis of mono-, bi-, and tetra-nuclear early transition metal–imido complexes
  作者：J.M Benito、Silvia Arévalo、E de Jesús*、F.J de la Mata、J.C Flores*、R Gómez

  DOI：10.1016/s0022-328x(00)00391-0

  日期：2000.9

  The siloxyanilines o-Me(3)SiOC(6)H(4)NH(2) (1) and p-RMe(2)SiOC(6)H(4)NH(2) (R = H (2); R = Me (3)), and their N-silylated derivatives p-Me(3)SiOC(6)H(4)NHSiMe(3) (4) and p-Me(3)SiOC(6)H(4)N(SiMe(3))(2) (5) have been prepared from ortho- or para-aminophenol and used in the synthesis of imido complexes. Thus, binuclear [Ti(eta (5)-C(5)H(5))Cl} mu -NC(6)H(4)(p-OSiMe(3))}](2) (6) and mononuclear [TiCl(2)NC(6)H(4)(p-OSiMe(3))}(py)(3)] (7) imido complexes have been obtained from the reaction of 3 and [Ti(eta (5)-C(5)H(5))Cl(3)] or [TiCl(2)(N'Bu)(py)(3)], respectively. In contrast, the reaction of 1 with TiCl(4) and 'Bupy affords the titanocycle [TiCl(2)OC(6)H(4)(o-NH)-N,O}('Bupy)(2)] (8). Compound 5 has also been used to prepare the niobium imide complex [NbCl(3)NC(6)H(4)(p-OSiMe(3))}(MeCN)(2)] (9), by its reaction with NbCl(5) in CH(3)CN. These findings have been applied to the synthesis of polynuclear systems. Thus, chlorocarbosilane Si[CH(2)CH(2)CH(2)Si(Me)(2)Cl], (CS-Cl) has been functionalized with the ortho- and para-aminophenoxy groups to give 10 and 11, respectively. The use of 11 has allowed the formation of the tetranuclear compound 12. Attempts to synthesize terminal imido titanium complexes from 10 and TiCl(4) in the presence of 'Bupy and Et(3)N, give complex 8 and carbosilane CS-Cl. (C) 2000 Elsevier Science S.A. All rights reserved.