ethyl 3-ethylhex-2-enoate | 1150667-94-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 3-ethylhex-2-enoate
• 英文别名: Ethyl 3-ethylhex-2-enoate
• CAS: 1150667-94-9
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: AMDBYGYJCYMGJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  ethyl 3-ethylhex-2-enoate 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 4.0h， 以85%的产率得到3-ethylhex-2-en-1-ol
  参考文献：
  名称：

  Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring

  摘要：

  A number of permethrinic acid ethyl ester derivatives having various substituents [Et, Pr, Ph, Ph(CH2)n (n = 1, 2), etc.] in position 2 of the cyclopropane ring were synthesized, and their insecticidal acivity against typhoid flies., rice weevils, and bean aphides, as well as juvenoid activity on flour beetle chrysalises, was studied. The newly synthesized Compounds turned out to exhibit weak insecticidal activity against standard insects but pronounced juvenile hormone activity, which differentiates them from permethrinic acid esters.

  DOI：

  10.1134/s107042800808006x
• 作为产物：
  描述：

  磷酰基乙酸三乙酯 、 3-己酮 在 potassium tert-butylate 作用下， 以 苯 为溶剂， 反应 12.0h， 以76%的产率得到ethyl 3-ethylhex-2-enoate
  参考文献：
  名称：

  Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring

  摘要：

  A number of permethrinic acid ethyl ester derivatives having various substituents [Et, Pr, Ph, Ph(CH2)n (n = 1, 2), etc.] in position 2 of the cyclopropane ring were synthesized, and their insecticidal acivity against typhoid flies., rice weevils, and bean aphides, as well as juvenoid activity on flour beetle chrysalises, was studied. The newly synthesized Compounds turned out to exhibit weak insecticidal activity against standard insects but pronounced juvenile hormone activity, which differentiates them from permethrinic acid esters.

  DOI：

  10.1134/s107042800808006x

文献信息

• Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring
  作者：N. S. Mirzabekova、N. E. Kuz’mina、O. I. Lukashov、N. A. Sokolova、S. N. Golosov、P. V. Kazakov、T. G. Perlova、V. V. Potapova、V. A. Kheinman、G. B. Ivanova

  DOI：10.1134/s107042800808006x

  日期：2008.8

  A number of permethrinic acid ethyl ester derivatives having various substituents [Et, Pr, Ph, Ph(CH2)n (n = 1, 2), etc.] in position 2 of the cyclopropane ring were synthesized, and their insecticidal acivity against typhoid flies., rice weevils, and bean aphides, as well as juvenoid activity on flour beetle chrysalises, was studied. The newly synthesized Compounds turned out to exhibit weak insecticidal activity against standard insects but pronounced juvenile hormone activity, which differentiates them from permethrinic acid esters.