3,3,4-trimethyldec-1-en-4-ol | 74120-67-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,3,4-trimethyldec-1-en-4-ol
• CAS: 74120-67-5
• 化学式: C₁₃H₂₆O
• 分子量: 198.349
• InChiKey: IIHKTVFGYCVMAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-methyl-1-(phenylsulfonyl)but-2-ene 以63%的产率得到
  参考文献：
  名称：

  Cydnt Jonathan, Julla Mare, J. Chem. Soc. Chem. Commun, (1994) N 19, S 2261-2262

  摘要：

  DOI：

文献信息

• Preparation of active zinc by reduction of zinc chloride with sodium in liquid ammonia and its use in the barbier reaction
  作者：Mieczysław Mąkosza、Karol Grela

  DOI：10.1016/0040-4039(95)01948-h

  日期：1995.12

  Active zine powder produced by reduction of anhydrous zine chloride with solution of sodium in liquid ammonia exhibits high reactivity in the Barbier type reaction both in THF and liquid ammonia solution.

  通过用钠在液态氨中的溶液还原无水氯化锌而生产的活性锌粉末在Barbier型反应中在THF和液态氨溶液中均显示出高反应活性。
• Homoallylic alcohols from samarium diiodide-mediated coupling of allylic sulfones with carbonyl compounds
  作者：Jonathan Clayden、Marc Julia

  DOI：10.1039/c39940002261

  日期：——

  Reduction of allylic sulfones with samarium diiodide gives allylsamarium species which react in situ with carbonyl compounds, yielding homoallylic alcohols.

  三碘化二钐还原烯丙基砜生成烯丙基钐物种，该物种可原地与羰基化合物反应，生成高烯丙醇。
• Preparation and reactions of samarium diiodide in nitriles
  作者：Béatrice Hamann、Jean-Louis Namy、Henri B. Kagan

  DOI：10.1016/0040-4020(96)00861-7

  日期：1996.11

  Samarium diiodide can be prepared from samarium metal in various nitriles. Because of its chemical inertness pivalonitrile is the most suitable solvent. Organic reactions mediated by SmI2 are slower than in THF, but selectivities are often improved. Reactions are greatly accelerated by addition of catalytic amounts of some transition metal salts.

  可以从各种腈中的金属metal制备二碘化prepared。由于其化学惰性，新戊腈是最合适的溶剂。由SmI 2介导的有机反应比在THF中慢，但选择性通常得到改善。通过加入催化量的某些过渡金属盐，可大大加快反应速度。
• Allylic Phosphates as Allyl Anion Synthons. Lithium-induced Allylation of Carbonyl Compounds
  作者：Shuki Araki、Yasuo Butsugan

  DOI：10.1246/cl.1988.457

  日期：1988.3.5

  Ultrasonication of allylic phosphates and carbonyl compounds with a lithium powder gave high yields of the corresponding homoallylic alcohols.

  使用锂粉超声处理烯丙基磷酸酯和羰基化合物，可以高产率地得到相应的高烯丙醇。
• Samarium(II)-mediated reaction of allylic phosphate esters with carbonyl compounds: A new method for “Umpolung” of allylic phosphates
  作者：Shuki Araki、Masahiro Hatano、Hirokazu Ito、Yasuo Butsugan

  DOI：10.1016/s0022-328x(00)99810-3

  日期：1987.10

  Allylic phosphates allylate ketones and aldehydes in the presence of samarium(II) iodide. The coupling proceeds with the preservation of the olefin geometry, however, regio- and stereoselectivity are not high.

  烯丙基磷酸酯在碘化sa（II）的存在下使酮和醛烯丙基化。偶联随着烯烃几何形状的保持而进行，但是，区域选择性和立体选择性不高。