(2E,4E)-3,7-dimethylocta-2,4-dienal | 137046-94-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2E,4E)-3,7-dimethylocta-2,4-dienal
• CAS: 137046-94-7
• 化学式: C₁₀H₁₆O
• 分子量: 152.236
• InChiKey: VVIABXRTIAZQSI-AGLLBGTNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-methyl-6-methylene-8,8-diethoxyoctan-4-ol 在 水 、 氢溴酸 作用下， 以 丙酮 为溶剂， 反应 1.0h， 生成 (2Z,4E)-3,7-dimethylocta-2,4-dienal 、 (2E,4E)-3,7-dimethylocta-2,4-dienal
  参考文献：
  名称：

  Preparation of 3-bromomethyl-3-butenal diethylacetal and its conversion into isoprenoid aldehydes derivatives

  摘要：

  The cyclopropanation of ethyl 3,3-diethoxypropionate with alkoxytitanacyclopropane reagents followed by the cleavage of the three-membered carbocycle in the formed cyclopropyl mesylate provided in a good yield 3-bromomethyl-3-butenal diethylacetal. The latter was brought into reactions of aldehyde allylation and cross-coupling with allyl halides in the intermediate stages at the generation of carbanionic intermediates. The conversion of compounds obtained into the corresponding beta, gamma- or alpha,beta-unsaturated aldehydes demonstrated the opportunity of applying 3-bromomethyl-3-butenal diethylacetal as a C-5-isoprenoid building block.

  DOI：

  10.1134/s1070428009110086

文献信息

• AEROSOL COMPOSITIONS
  申请人：The Procter & Gamble Company

  公开号：EP3509562B1

  公开（公告）日：2021-06-23
• Preparation of 3-bromomethyl-3-butenal diethylacetal and its conversion into isoprenoid aldehydes derivatives
  作者：I. V. Mineeva、O. G. Kulinkovich

  DOI：10.1134/s1070428009110086

  日期：2009.11

  The cyclopropanation of ethyl 3,3-diethoxypropionate with alkoxytitanacyclopropane reagents followed by the cleavage of the three-membered carbocycle in the formed cyclopropyl mesylate provided in a good yield 3-bromomethyl-3-butenal diethylacetal. The latter was brought into reactions of aldehyde allylation and cross-coupling with allyl halides in the intermediate stages at the generation of carbanionic intermediates. The conversion of compounds obtained into the corresponding beta, gamma- or alpha,beta-unsaturated aldehydes demonstrated the opportunity of applying 3-bromomethyl-3-butenal diethylacetal as a C-5-isoprenoid building block.