2-bromo-11-undecanol | 73641-91-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-bromo-11-undecanol
• 英文别名: 10-bromo-undecan-1-ol；κ-Brom-undecylalkohol；10-Brom-undecan-1-ol；10-bromoundecan-1-ol
• CAS: 73641-91-5
• 化学式: C₁₁H₂₃BrO
• 分子量: 251.207
• InChiKey: KUNKXWCSYLVRJU-UHFFFAOYSA-N

物化性质

• 沸点：
  168-169 °C(Press: 15 Torr)
• 密度：
  1.135±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  13
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-bromo-11-undecanol 在 氢溴酸 作用下， 生成 1,10-dibromoundecane
  参考文献：
  名称：

  Chuit et al., Helvetica Chimica Acta, 1926, vol. 9, p. 1086

  摘要：

  DOI：
• 作为产物：
  描述：

  10-十一烯-1-醇 在 氢溴酸 作用下， 生成 2-bromo-11-undecanol
  参考文献：
  名称：

  Chuit et al., Helvetica Chimica Acta, 1926, vol. 9, p. 1086

  摘要：

  DOI：

文献信息

• Compositions of iodophenoxy alkanes and iodophenyl ethers and
  申请人：Sterling Winthrop Inc.

  公开号：US05531979A1

  公开（公告）日：1996-07-02

  Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising iodophenoxy alkanes and iodophenyl ethers as the x-ray producing agents in combination with a pharmaceutically acceptable clay in a pharmaceutically acceptable carrier; and methods for their use in diagnostic radiology of the gastrointestinal tract.

  揭示了用于口服或逆行检查消化道的X射线造影剂组合物，包括碘苯氧烷和碘苯醚作为X射线产生剂，与药学上可接受的粘土结合在药学上可接受的载体中；以及它们在消化道诊断放射学中的使用方法。
• Compositions of iodophenoxy alkanes and iodophenyl ethers in combination
  申请人：Sterling Winthrop Inc.

  公开号：US05607660A1

  公开（公告）日：1997-03-04

  Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising an iodophenoxy alkane, iodophenyl alkenylalkyl ether or an iodophenyl alkynylalkyl ether x-ray producing agent in combination with a cellulose derivative in a pharmaceutically acceptable carrier; and methods for their use in diagnostic radiology of the gastrointestinal tract.

  揭示了用于口服或逆行检查消化道的X射线造影剂，包括碘苯氧烷、碘苯烯基烷基醚或碘苯炔基烷基醚X射线造影剂，与纤维素衍生物结合在药学上可接受的载体中；以及它们在消化道诊断放射学中的使用方法。
• Compositions of iodophenoxy alkanes and iodophenyl ethers in
  申请人：Sterling Winthrop Inc.

  公开号：US05326553A1

  公开（公告）日：1994-07-05

  Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1## and methods for their use in diagnostic radiology of the gastrointestinal tract wherein Z=H, halo, C.sub.1 -C.sub.20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R=C.sub.1 -C.sub.25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxycarbonyloxy, (CR.sub.1 R.sub.2).sub.p-- (CR.sub.3 .dbd.CR.sub.4).sub.m Q, or (CR.sub.1 R.sub.2).sub.p --C.tbd.C--Q; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently lower-alkyl, optionally substituted with halo; x is 1-4; n is 1-5; m is 1-15; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl in a pharmaceutically acceptable carrier.

  揭示了用于口服或逆行检查消化道的X射线造影剂组合物，包括能够在消化道上形成涂层的聚合物材料和具有以下结构的X射线产生剂的方法：##STR1##以及它们在消化道诊断放射学中的使用方法，其中Z=H，卤素，C.sub.1-C.sub.20烷基，环烷基，较低烷氧基，氰基，其中烷基和环烷基基团可被卤素或卤素较低烷基基团取代；R=C.sub.1-C.sub.25烷基，环烷基，或卤素较低烷基，可选择地被卤素，氟代较低烷基，芳基，较低烷氧基，羟基，羧基，较低烷氧基羰基或较低烷氧羰氧基，(CR.sub.1 R.sub.2).sub.p--(CR.sub.3.dbd.CR.sub.4).sub.m Q，或(CR.sub.1 R.sub.2).sub.p--C.tbd.C--Q；R.sub.1，R.sub.2，R.sub.3和R.sub.4独立地为较低烷基，可选择地被卤素取代；x为1-4；n为1-5；m为1-15；p为1-10；Q为H，较低烷基，较低烯基，较低炔基，较低烷基烯，芳基，或芳基-较低烷基，位于药学上可接受的载体中。
• Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
  申请人：Gemin X Biotechnologies Inc.

  公开号：US20040014987A1

  公开（公告）日：2004-01-22

  The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell. The present invention also relates to novel Pyrrole-Type compounds, compositions, and methods useful for treating or preventing a viral infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the replication and/or infectivity of a virus.

  本发明涉及新型吡咯烷类化合物，包含吡咯烷类化合物的组合物，以及用于治疗或预防癌症或肿瘤性疾病的方法，包括给予含有吡咯烷类化合物的组合物。本发明的化合物、组合物和方法还可用于抑制癌细胞或肿瘤细胞的生长。本发明还涉及新型吡咯烷类化合物、组合物和用于治疗或预防病毒感染的方法。本发明的化合物、组合物和方法还可用于抑制病毒的复制和/或传染性。
• Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
  申请人：——

  公开号：US20030009032A1

  公开（公告）日：2003-01-09

  The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell. The present invention also relates to novel Pyrrole-Type compounds, compositions, and methods useful for treating or preventing a viral infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the replication and/or infectivity of a virus.

  本发明涉及一种新型吡咯类化合物，包含吡咯类化合物的组合物以及用于治疗或预防癌症或肿瘤性疾病的方法，其中包括给予包含吡咯类化合物的组合物。本发明的化合物、组合物和方法还可用于抑制癌细胞或肿瘤细胞的生长。本发明还涉及一种新型吡咯类化合物、组合物和方法，用于治疗或预防病毒感染。本发明的化合物、组合物和方法还可用于抑制病毒的复制和/或感染能力。