N,N-dimethyl-4-((1E,3E)-4-(quinolin-2-yl)butyl-1,3-dien-1-yl)aniline | 28496-04-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N,N-dimethyl-4-((1E,3E)-4-(quinolin-2-yl)butyl-1,3-dien-1-yl)aniline
• 英文别名: 4-(4t-[2]quinolyl-buta-1,3-dien-t-yl)-N,N-dimethyl-aniline；4-(4t-[2]Chinolyl-buta-1,3-dien-t-yl)-N,N-dimethyl-anilin；N,N-dimethyl-4-[(1E,3E)-4-quinolin-2-ylbuta-1,3-dienyl]aniline
• CAS: 28496-04-0
• 化学式: C₂₁H₂₀N₂
• 分子量: 300.403
• InChiKey: OAOWLMFSBDUJAE-DLYLGUBQSA-N

物化性质

• 沸点：
  517.8±43.0 °C(Predicted)
• 密度：
  1.135±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  16.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲基喹啉 、 3-(4-dimethylamino-phenyl)-propenal 在 盐酸 作用下， 生成 N,N-dimethyl-4-((1E,3E)-4-(quinolin-2-yl)butyl-1,3-dien-1-yl)aniline
  参考文献：
  名称：

  Color and Constitution. III.¹ Absorption of 2-p-Dimethylaminostyrylquinoline and Its Salts. The Effect on Absorption of a Benzene Ring in the Chromophoric Chain of Dyes²

  摘要：

  DOI：

  10.1021/ja01856a087

文献信息

• ANTI-NEURODEGENERATIVE DISEASE AGENT
  申请人：Ohta Hitomi

  公开号：US20120035187A1

  公开（公告）日：2012-02-09

  The present invention has an object to provide a novel agent for anti-neurodegenerative diseases and solves the object by providing an agent for anti-neurodegenerative diseases containing, as an effective ingredient, the compound(s) represented by the following General formula 1: wherein in General formula 1, R 1 through R 3 independently represent a hydrogen atom or an appropriate substituent; Z 1 represents a heterocyclic ring and Z 2 represents the same or different heterocyclic or aromatic ring as in Z 1 , wherein the heterocyclic and aromatic rings optionally have a substituent; represents an integer of 0, 1 or 2; p represents an integer of 0 or 1, with the proviso that p is 1 when o is 0 or 2, and p is 0 when o is 1; R 1 and R 2 do not exist when o is 0, while, when p is 0, R 3 does not exist and the binding between the carbon atom to which R 2 binds and Z 2 is a single bond; X 1 − represents an appropriate counter anion and q represents an integer of 1 or 2.
• Color and Constitution. III.¹ Absorption of 2-p-Dimethylaminostyrylquinoline and Its Salts. The Effect on Absorption of a Benzene Ring in the Chromophoric Chain of Dyes²
  作者：L. G. S. Brooker、R. H. Sprague

  DOI：10.1021/ja01856a087

  日期：1941.11