6-methyl-1-oxa-spiro[4.5]decan-2-one | 16332-62-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 6-methyl-1-oxa-spiro[4.5]decan-2-one
• 英文别名: 6-Methyl-1-oxa-spiro[4.5]decan-2-on；6-Methyl-1-oxaspiro[4.5]decan-2-one
• CAS: 16332-62-0
• 化学式: C₁₀H₁₆O₂
• 分子量: 168.236
• InChiKey: YQZXHPKKULNKSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-methyl-1-oxa-spiro[4.5]decan-2-one 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 以92%的产率得到2-Methyl-1-(3-hydroxypropyl)cyclohexanol
  参考文献：
  名称：

  分子间和分子内偶联中羰基和烯酮体系之间电解和二碘化钐诱导环化的立体化学

  摘要：

  使用二碘化钐和电解对具有α，β-不饱和羰基系统的羰基化合物进行分子间和分子内环化。产品的立体化学相互比较。

  DOI：

  10.3987/com-06-s(k)45
• 作为产物：
  描述：

  反-1,3-戊二烯 在 palladium on activated charcoal 氢气 、 对苯二酚 作用下， 25.0~150.0 ℃ 、202.65 kPa 条件下， 反应 4.0h， 生成 6-methyl-1-oxa-spiro[4.5]decan-2-one
  参考文献：
  名称：

  General synthesis of 1-oxaspiro[4.5]decan-2-ones and 1-oxaspiro[4.5]decanes from 5-methylene-2(5H)-furanone

  摘要：

  5-Methylene-2(5H)-furanone underwent Diels-Alder cycloadditions to butadiene and several acyclic and cyclic C-substituted dienes, respectively, affording bicyclic and tricyclic spiroadducts in good yields. These compounds are precursors of other unsaturated and saturated spirolactones and also spiroethers, which were obtained through simple chemical reactions, i.e., hydrogenation of C-C double bonds, reduction of the carbonyl group, and Michael addition. The synthesis of 32 spirolactones and eight spiroethers illustrates the scope and efficiency of this method. Many of these products are suitable for use as components of perfumes and aromas owing to their olfactive properties.

  DOI：

  10.1021/jo00019a019

文献信息

• A FRAGRANCE-DELIVERY COMPOSITION COMPRISING PERSULFATE ION-CROSSLINKED POLYVINYL ALCOHOL MICROCAPSULES AND METHOD OF USE THEREOF
  申请人：APPVION, INC.

  公开号：EP2907568A1

  公开（公告）日：2015-08-19

  An aqueous composition is provided having a pH of from about 2.0 to about 5.7 to about 12.8 and comprising boron or persulfate ion-crosslinked polyvinyl alcohol microcapsules. A method of delivering a fragrance to a substrate is further provided comprising applying to the substrate an aqueous composition comprised of fragrance-containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules, as well as a method of cleaning a substrate comprising applying to the substrate an aqueous composition comprised of fragrance-containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules together with at least one cleaning component.

  本发明提供了一种水性组合物，其 pH 值为约 2.0 至约 5.7 至约 12.8，并包含硼或过硫酸根离子交联的聚乙烯醇微胶囊。本发明还提供了一种向基底输送香料的方法，包括向基底施用由含香、硼或过硫酸根离子交联的聚乙烯醇微胶囊组成的水性组合物，以及一种清洁基底的方法，包括向基底施用由含香、硼或过硫酸根离子交联的聚乙烯醇微胶囊组成的水性组合物和至少一种清洁成分。
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  作者：Edward, John T.、Cooke, Ellen、Paradellis, Themistocles C.

  DOI：——

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  作者：W. E. Bachmann、E. K. Raunio

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  作者：Chatterjee、Bhattacharyya

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  作者：EDWARD J. T.、 COOKE E.、 PARADELLIS T. C.

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  日期：——