Bn(-2)[Bz(-3)][Bz(-4)][Bz(-6)]Glc(?1-6)[Bn(-2)][Bn(-3)][Bn(-4)]a-Glc1Me | 1233488-81-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Bn(-2)[Bz(-3)][Bz(-4)][Bz(-6)]Glc(?1-6)[Bn(-2)][Bn(-3)][Bn(-4)]a-Glc1Me
• 英文别名: [(2R,3R,4S,5R)-3,4-dibenzoyloxy-6-[[(2R,3R,4S,5R,6S)-6-methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methoxy]-5-phenylmethoxyoxan-2-yl]methyl benzoate
• CAS: 1233488-81-7
• 化学式: C₆₂H₆₀O₁₄
• 分子量: 1029.15
• InChiKey: YHYKFQLXFFXEQT-ANVCHJSASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.1
• 重原子数：
  76
• 可旋转键数：
  26
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  153
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为产物：
  描述：

  甲基2,3,4-三-O-苄基-α-D-吡喃葡萄糖苷 、 ethyl 3,4,6-tri-O-benzoyl-2-O-benzyl-1-thio-β-D-glucopyranoside 、 ethyl 3,4,6-tri-O-benzoyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 在 碘 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 49.0h， 以53%的产率得到methyl 3,4,6-tri-O-benzoyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1→6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside
  参考文献：
  名称：

  Comparison of the Armed/Disarmed Building Blocks of the d-Gluco and d-Glucosamino Series in the Context of Chemoselective Oligosaccharide Synthesis

  摘要：

  A very elegant Fraser-Reid armed-disarmed approach recently expanded to the building blocks of the superarmed and superdisarmed series shows very high utility in chemoselective oligosaccharide synthesis. Although a number of studies dedicated to the chemoselective activation of 2-amino-2-deoxysugars have emerged, little remains known about how the reactivity of the armed/disarmed building blocks of the neutral sugars directly compares to that of their 2-aminosugar counterparts. A preliminary study of this comparative reactivity is presented.

  DOI：

  10.1021/ol101089u