6-hydroxynonanoic acid | 75544-91-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: 6-hydroxynonanoic acid
• 英文别名: 6-Hydroxy-nonansaeure；6-Hydroxy-nonanoic acid
• CAS: 75544-91-1
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: USHAAPGWFOVBJE-UHFFFAOYSA-N

物化性质

• 沸点：
  100 °C(Press: 1.7 Torr)
• 密度：
  1.027±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-hydroxynonanoic acid 在 乙醇 、 氢溴酸 、 溶剂黄146 作用下， 生成 2-propyl-1,7-heptandioic acid
  参考文献：
  名称：

  Yamakawa, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1950, vol. 70, p. 633,635,637

  摘要：

  DOI：
• 作为产物：
  描述：

  6-羟基己酸 在 2-iodoxybenzoic acid 作用下， 以 四氢呋喃 、 二甲基亚砜 为溶剂， 反应 6.0h， 生成 6-hydroxynonanoic acid
  参考文献：
  名称：

  Synthesis of a Series of Hydroxycarboxylic Acids as Standards for Oxidation of Nonanoic Acid

  摘要：

  The synthesis of a series of nonanoic acids hydroxylated in terminal,omega-1,omega-2,omega-3 positions is described. These compounds will be employed as useful standards for the study of enzymatic and microbiological oxidation of nonanoic acid. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2013.853800

文献信息

• [EN] DRUG CONJUGATES<br/>[FR] CONJUGUÉS DE MÉDICAMENT
  申请人：UNIV MISSOURI

  公开号：WO2009158633A1

  公开（公告）日：2009-12-30

  Conjugated compounds comprising a therapeutic or diagnostic agent linked to a substrate for a cell membrane transporter or receptor by lipophilic linker are provided.

  提供了包含治疗或诊断药物与细胞膜转运体或受体的底物通过亲脂性连接剂连接的共轭化合物。
• Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester, and intermediate therefor
  申请人：Ajinomoto Co., Inc.

  公开号：EP0759424A1

  公开（公告）日：1997-02-26

  Optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4-arylbutyric acid, which can then be converted into an optically active 2-acyloxy-4-arylbutyric acid by catalytic reduction, and the latter compound hydrolyzed in the presence of an acid or an alkali to produce an optically active 2-hydroxy-4-arylbutyric acid, which can optionally be reacted with an alcohol in the presence of an acid to produce an optically active 2-hydroxy-4-arylbutyric acid ester.

  具有光学活性的酰氧基丁二酸酐在路易斯酸存在下与芳香族化合物反应，生成具有光学活性的 2-乙酰氧基-4-氧代-4-芳基丁酸，然后可通过催化还原转化为具有光学活性的 2-乙酰氧基-4-芳基丁酸、后一种化合物在有酸或碱存在的情况下水解，生成光学活性 2-羟基-4-芳基丁酸，后者可选择在有酸存在的情况下与醇反应，生成光学活性 2-羟基-4-芳基丁酸酯。
• SUSTAINED RELEASE PHEROMONE PREPARATION AND METHOD FOR CONTROLLING INSECT PEST USING THE SAME
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3427582A1

  公开（公告）日：2019-01-16

  There are provided a sustained release pheromone preparation capable of prolonged release of a pheromone substance without the need to increase the membrane thickness, and a method for controlling an insect pest using the same. More specifically, there is provided a sustained release pheromone preparation including: at least one pheromone substance and a container for enclosing the pheromone substance therein, the container comprising a polymer membrane which includes a polymer blend of: an aliphatic polyester of general formula (1) below; and a poly(hydroxyalkanoate) of general formula (2) below. There is also provided a method of controlling an insect pest, including a step of installing the sustained release pheromone preparation in a field to allow the pheromone substance to permeate through the polymer membrane and to be released into the field.

  本发明提供了一种能够延长信息素物质释放时间而无需增加膜厚度的持续释放信息素制剂，以及使用该制剂控制害虫的方法。更具体地说，本发明提供了一种持续释放信息素制剂，包括：至少一种信息素物质和一个用于将信息素物质封闭在其中的容器，该容器包括一个聚合物膜，该聚合物膜包括以下聚合物混合物：通式（1）的脂肪族聚酯；和通式（2）的聚（羟基烷酸）。还提供了一种控制害虫的方法，包括将持续释放信息素制剂安装在田地中，使信息素物质渗透过聚合物膜并释放到田地中。
• Lardelli,G. et al., Recueil des Travaux Chimiques des Pays-Bas, 1967, vol. 86, p. 481 - 503
  作者：Lardelli,G. et al.

  DOI：——

  日期：——
• GULACAR, FAZIL O.;BUCHS, ARMAND;SUSINI, ALBERTO, J. CHROMATOGR., 479,(1989) N, C. 61-72
  作者：GULACAR, FAZIL O.、BUCHS, ARMAND、SUSINI, ALBERTO

  DOI：——

  日期：——