1,2-dimethylquinolinium | 18241-36-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1,2-dimethylquinolinium
• 英文别名: 1,2-Dimethylchinolinium；1,2-dimethylquinolin-1-ium；2,N-Dimethyl-chinolinium；N-Methyl-chinaldinium；1-Methyl-chinaldinium
• CAS: 18241-36-6
• 化学式: C₁₁H₁₂N
• mdl: MFCD00050320
• 分子量: 158.223
• InChiKey: KEOLYURDXNRJEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2-dimethylquinolinium 在 三(三甲基硅基)硅烷 作用下， 以 乙腈 为溶剂， 生成 1,2-Dimethyl-1,4-dihydrochinolin
  参考文献：
  名称：

  Regioselective reduction of 1-methylquinolium ions by tributyltin hydride and tris(trimethylsilyl)silane via photoinduced electron transfer

  摘要：

  三丁基氢化锡对 1-甲基喹啉离子的热还原是通过极性机制进行的，从而选择性地生成 1-甲基-1,2-二氢喹啉；而三丁基氢化锡和三(三甲基硅基)硅烷对 1-甲基喹啉离子衍生物的光还原则是通过光诱导电子从金属氢化物转移到 1-甲基喹啉离子衍生物的单激发态，从而完全生成相应的 1,4-二氢喹啉。

  DOI：

  10.1039/c39940000287

文献信息

• THIOL DYES
  申请人：Eliu Victor Paul

  公开号：US20090113639A1

  公开（公告）日：2009-05-07

  Disclosed are thiol dyes of formula (1), wherein R 1 is hydrogen; C 1 -C 12 alkyl; or phenyl-C 1 -C 4 alkyl; X is C 1 -C 12 alkylene; C 2 -C 12 alkenylene; C 5 -C 10 cycloalkylene; C 5 -C 10 arylene; or C 5 -C 10 arylene-C 1 -C 10 alkylene; Y is the residue of an organic dye which corresponds to the formula (1a), wherein R 2 is hydrogen; or C 1 -C 5 alkyl; R 3 is a radical of formula (1a 1 ): (1a 2 ); or (1a 3 ); or R 2 and R 3 together with the linking carbon atom 1 C form a 6 to 10 membered carbocyclic ring which may optionally be a condensated aromatic system and may contain one or more than one hetero atom; and R 4 , R 5 and R 6 independently form each other are hydrogen, or C 1 -C 5 alkyl; Z is H; or a thio ester group of formula (1b), wherein A is O; S; or N—R9; B is —OR7; —NR7R8, or —SR7; and A is O; S; or N—R 9 ; B is —OR 7 ; —NR 7 R 8 , or —SR 7 ; and R 7 , R 8 and R 9 , independently from each other are hydrogen; C 1 -C 12 alkyl C 6 -C 12 aryl; or C 6 -C 12 aryl-C 1 -C 12 alkyl. The compounds are useful for the dyeing of organic materials, such as keratin fibers, preferably human hair.

  揭示了式（1）的硫醇染料，其中R1为氢；C1-C12烷基；或苯基-C1-C4烷基；X为C1-C12亚烷基；C2-C12烯亚烷基；C5-C10环烷基；C5-C10芳基；或C5-C10芳基-C1-C10亚烷基；Y为与式（1a）对应的有机染料的残基，其中R2为氢；或C1-C5烷基；R3为式（1a1）的基团：（1a2）；或（1a3）；或R2和R3与连接碳原子1C形成6至10成员的碳环，该碳环可以选择性地是一个缩合芳香系统，并且可以含有一个或多个杂原子；以及R4，R5和R6独立地形成彼此为氢，或C1-C5烷基；Z为H；或式（1b）的硫酯基团，其中A为O；S；或N—R9；B为—OR7；—NR7R8，或—SR7；而A为O；S；或N—R9；B为—OR7；—NR7R8，或—SR7；且R7，R8和R9，彼此独立地为氢；C1-C12烷基；C6-C12芳基；或C6-C12芳基-C1-C12烷基。这些化合物适用于有机材料的染色，例如角蛋白纤维，最好是人类头发。
• Synthesis of Near-Infrared Absorbing Bisquarylium Dyes Bearing Unsymmetrically Extended π-Conjugation Structures
  作者：Shigeyuki Yagi、Kazuhisa Nakai、Yutaka Hyodo、Hiroyuki Nakazumi

  DOI：10.1055/s-2002-20034

  日期：——

  Novel cationic bisquarylium dyes 3 and 4 were prepared by the reaction of benzothiazolinosquarylium dye 2 with a series of 4-substituted 3-hydroxy or 3-ethoxycyclobut-3-ene-1,2-diones. These dyes exhibit large and intense absorptions in the near-infrared region with varying absorption maxima in the range of 771 to 815 nm.

  新型阳离子双菁染料3和4是通过苯并噻唑基菁染料2与一系列4-取代的3-羟基或3-乙氧基环丁-3-烯-1,2-二酮反应制备的。这些染料在近红外区域显示出大且强烈的吸收，吸收峰位置在771至815纳米范围内变化。
• [EN] DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION<br/>[FR] COMPOSITION COLORANTE COMPRENANT AU MOINS UN PRÉCURSEUR DE DISULFURE/THIOL INCOLORE ET PROCÉDÉ DE TEINTURE UTILISANT LA COMPOSITION
  申请人：OREAL

  公开号：WO2009040354A1

  公开（公告）日：2009-04-02

  The present invention relates to the dyeing of keratin materials using two colorless dye precursors, at least one of which contains a disulfide/thiol unit, said precursors reacting together chemically to form the color in situ. The process according to the invention makes it possible in the context of certain variants to solve the problems caused by the color generated during the process, while at the same time not degrading the efficacy of the coloration, and especially of the lightening effect. The colorations obtained are moreover powerful, chromatic, sparingly selective, and fast with respect to external agents such as sunlight, perspiration and especially shampoo.

  本发明涉及使用两种无色染料前体对角蛋白材料进行染色，其中至少一种含有二硫化物/巯基单元，这些前体在化学上相互反应以在原位形成颜色。根据本发明的方法使得在某些变体情况下能够解决染色过程中产生的问题，同时不降低染色的功效，特别是减淡效果。所获得的染色品不仅强大、色彩鲜艳、选择性较少，而且对于阳光、汗水和尤其是洗发水等外部因素具有快速的耐久性。
• Parallel Synthesis and Screening of Supramolecular Chemosensors That Achieve Fluorescent Turn-on Detection of Drugs in Saliva
  作者：Meagan A. Beatty、Allison J. Selinger、YuQi Li、Fraser Hof

  DOI：10.1021/jacs.9b07073

  日期：2019.10.23

  solutions is increasingly common, but creating supramolecular sensors that detect analytes in biologically relevant solutions remains a non-trivial task. We report here a parallel synthesis-driven approach to create a family of self-assembling dimeric sensors that we call DimerDyes, and its use for the rapid identification of salt-tolerant sensors for illicit drugs. We developed an efficient method that involves

  对水溶液中的分子识别进行编程和控制越来越普遍，但创建检测生物相关溶液中分析物的超分子传感器仍然是一项重要的任务。我们在此报告了一种平行合成驱动的方法，用于创建我们称为 DimerDyes 的自组装二聚体传感器家族，并将其用于快速识别非法药物的耐盐传感器。我们开发了一种有效的方法，该方法涉及以粗制形式进行平行合成和筛选，而无需纯化每个潜在的传感器。结构多样的“命中”二聚体染料被重新合成、纯化，并且每一种都以程序化的方式在水中组装成同型二聚体。DimerDyes 提供了“开启” 水和唾液中低微摩尔浓度的多种非法药物的荧光检测。将多种药剂组合到传感器阵列中，能够成功地检测和区分多个重要药物家族中密切相关的药物和代谢物。
• Focused Fluorescent Probe Library for Metal Cations and Biological Anions
  作者：Hyun-Woo Rhee、Sang Wook Lee、Jun-Seok Lee、Young-Tae Chang、Jong-In Hong

  DOI：10.1021/co400034x

  日期：2013.9.9

  A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent

  通过结合金属螯合剂和吡啶鎓/喹啉鎓部分作为通过苯乙烯基连接的组合嵌段，开发了针对金属阳离子的聚焦荧光探针库。此外，衍生自对金属阳离子具有高结合亲和力的金属螯合剂的金属络合物用于构建磷酸化生物分子的聚焦探针库。筛选了250多种荧光探针，以鉴定dTTP的超选择性探针。