2-乙基-2-戊基-1,3-二氧戊环-4-甲醇 | 5754-25-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-乙基-2-戊基-1,3-二氧戊环-4-甲醇
• 英文名称: (2-ethyl-2-pentyl-[1,3]dioxolan-4-yl)-methanol
• 英文别名: (2-Aethyl-2-pentyl-[1,3]dioxolan-4-yl)-methanol；2-Ethyl-2-pentyl-1,3-dioxolane-4-methanol；(2-ethyl-2-pentyl-1,3-dioxolan-4-yl)methanol
• CAS: 5754-25-6
• 化学式: C₁₁H₂₂O₃
• 分子量: 202.294
• InChiKey: SIGRDOVOVHZTGC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-辛酮 、 甘油 在 对甲苯磺酸 、 甲苯 作用下， 生成 2-乙基-2-戊基-1,3-二氧戊环-4-甲醇
  参考文献：
  名称：

  Drugs Effecting Muscular Paralysis. Some Substituted Dioxolanes and Related Compounds

  摘要：

  DOI：

  10.1021/ja01178a009

文献信息

• METHOD FOR PRODUCING GLYCERIC ACID ESTER
  申请人：Kao Corporation

  公开号：EP3564226A1

  公开（公告）日：2019-11-06

  The present invention relates to providing a novel glyceric acid ester which can be produced in a high yield and is expected to be applied as a synthetic intermediate, and a method of producing the same. In addition, the present invention relates to providing a novel glyceric acid ester which exhibits a high recovery in a water-washing step after the reaction and a small work load at the time of production, and is expected to be applied as a synthetic intermediate, and a method of producing the same. The present invention provides a method of producing a compound represented by the following formula (II), including a step of oxidatively esterifying a compound represented by the following formula (I): wherein, in the formulae (I) and (II), R1 and R2 each independently represent a hydrogen atom or a monovalent hydrocarbon group, or R1 and R2 are bonded to each other to form a divalent hydrocarbon group for constituting a ring structure, provided that the case where R1 and R2 are a methyl group at the same time is excluded.

  本发明涉及提供一种新型甘油酸酯，该甘油酸酯可以高产率生产，有望用作合成中间体，本发明还涉及生产该甘油酸酯的方法。此外，本发明还涉及提供一种新型甘油酸酯，该甘油酸酯在反应后的水洗步骤中表现出较高的回收率，且生产时的工作量较小，有望用作合成中间体，以及生产该甘油酸酯的方法。本发明提供了一种生产下式（II）代表的化合物的方法，包括氧化酯化下式（I）代表的化合物的步骤： 其中，在式(I)和(II)中，R1 和 R2 各自独立地代表氢原子或一价烃基，或 R1 和 R2 相互键合形成二价烃基，以构成环结构，但不包括 R1 和 R2 同时为甲基的情况。
• Method for producing glyceric acid ester
  申请人：KAO CORPORATION

  公开号：US10822329B2

  公开（公告）日：2020-11-03

  The present invention relates to providing a novel glyceric acid ester which can be produced in a high yield and is expected to be applied as a synthetic intermediate, and a method of producing the same. In addition, the present invention relates to providing a novel glyceric acid ester which exhibits a high recovery in a water-washing step after the reaction and a small work load at the time of production, and is expected to be applied as a synthetic intermediate, and a method of producing the same. The present invention provides a method of producing a compound represented by the following formula (II), including a step of oxidatively esterifying a compound represented by the following formula (I): wherein, in the formulae (I) and (II), R1 and R2 each independently represent a hydrogen atom or a monovalent hydrocarbon group, or R1 and R2 are bonded to each other to form a divalent hydrocarbon group for constituting a ring structure, provided that the case where R1 and R2 are a methyl group at the same time is excluded.

  本发明涉及提供一种新型甘油酸酯，该甘油酸酯可以高产率生产，有望用作合成中间体，本发明还涉及生产该甘油酸酯的方法。此外，本发明还涉及提供一种新型甘油酸酯，该甘油酸酯在反应后的水洗步骤中表现出较高的回收率，且生产时的工作量较小，有望用作合成中间体，以及生产该甘油酸酯的方法。本发明提供了一种生产下式（II）代表的化合物的方法，包括氧化酯化下式（I）代表的化合物的步骤： 其中，在式(I)和(II)中，R1和R2各自独立地代表氢原子或一价烃基，或者R1和R2相互键合形成二价烃基，以构成环状结构，但不包括R1和R2同时为甲基的情况。