(E)-1-(1-cyclohexyl-1-octenyl)cyclohexanol | 125642-03-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-1-(1-cyclohexyl-1-octenyl)cyclohexanol
• 英文别名: 1-[(E)-1-cyclohexyloct-1-enyl]cyclohexan-1-ol
• CAS: 125642-03-7
• 化学式: C₂₀H₃₆O
• 分子量: 292.505
• InChiKey: LTKGKKJIGKHWRJ-XDJHFCHBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  oct-1-yn-1-ylcyclohexane 、 环己酮 、 五氯化钽 生成 (E)-1-(1-cyclohexyl-1-octenyl)cyclohexanol
  参考文献：
  名称：

  TAKAI, KAZUHIKO;KATAOKA, YASUTAKA;UTIMOTO, KIITIRO, J. ORG. CHEM., 55,(1990) N, C. 1707-1708

  摘要：

  DOI：

文献信息

• Reactions between tantalum- or niobium-alkyne complexes and carbonyl compounds
  作者：Yasutaka Kataoka、Jiro Miyai、Koichiro Oshima、Kazuhiko Takai、Kiitiro Utimoto

  DOI：10.1021/jo00033a015

  日期：1992.3

  A variety of tantalum-alkyne complexes are generated in situ by treatment of alkynes with low-valent tantalum derived from TaCl5 and zinc. These complexes add regioselectively to carbonyl compounds in a one-to-one fashion to yield (E)-allylic alcohols stereoselectively. Iodinolysis of the oxatantalacyclopentene, which is postulated as an intermediate of the reaction, gives a (Z)-3-iodo-2-propen-1-ol derivation. In contrast to tantalum-alkyne complexes, niobium-alkyne complexes, prepared with low-valent niobium derived from NbCl5 and zinc, add in situ to aldehydes in a one-to-two fashion to give 1,3-diene derivatives. The dienes are produced through (i) addition of the alkyne complexes with 2 equiv of aldehydes at cis vicinal positions of the alkenes and (ii) deoxygenative elimination of 2,7-dioxanioba-4-cycloheptene complexes.
• Tantalum-alkyne complexes as synthetic intermediates. Stereoselective preparation of trisubstituted allylic alcohols from acetylenes and aldehydes
  作者：Kazuhiko Takai、Y. Kataoka、K. Utimoto

  DOI：10.1021/jo00293a008

  日期：1990.3
• TAKAI, KAZUHIKO;KATAOKA, YASUTAKA;UTIMOTO, KIITIRO, J. ORG. CHEM., 55,(1990) N, C. 1707-1708
  作者：TAKAI, KAZUHIKO、KATAOKA, YASUTAKA、UTIMOTO, KIITIRO

  DOI：——

  日期：——