bis(1-methyl-2-oxopropyl) sulfide | 113334-17-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: bis(1-methyl-2-oxopropyl) sulfide
• 英文别名: 3,5-Dimethyl-4-thia-heptan-2,6-dion；Bis-(1-methyl-2-oxo-propyl)-sulfid；3-(3-oxobutan-2-ylsulfanyl)butan-2-one
• CAS: 113334-17-1
• 化学式: C₈H₁₄O₂S
• 分子量: 174.264
• InChiKey: YGVGCMGLHWUOCP-UHFFFAOYSA-N

物化性质

• 沸点：
  109-111 °C(Press: 8 Torr)
• 密度：
  1.027±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
• 保留指数：
  1359

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  59.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(1-methyl-2-oxopropyl) sulfide 在 三氟化硼乙醚 、 四氯化钛 、 锌 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 3.0h， 生成 2,3,4,5-四甲基噻吩
  参考文献：
  名称：

  General synthesis of polysubstituted thiophenes from diketo sulfides

  摘要：

  DOI：

  10.1016/s0040-4039(00)98358-8
• 作为产物：
  描述：

  3-氯-2-丁酮 在 sodium hydrogensulfide 、 水 作用下， 生成 bis(1-methyl-2-oxopropyl) sulfide
  参考文献：
  名称：

  Über das 2,3,5,6-Tetramethyl-2,5-endoxy-1,4-dithian

  摘要：

  DOI：

  10.1007/bf00898709

文献信息

• Stereoselective synthesis of - and -1,2-diols from diketo sulfides via -3,4-dihydroxythiolanes
  作者：Juzo Nakayama、Shoji Yamaoka、Masamatsu Hoshino

  DOI：10.1016/s0040-4039(00)95425-x

  日期：1987.1

  Intramolecular reductive coupling reaction of a series of diketo sulfides () by a low-valent titanium reagent at 0 °C in tetrahydrofuran leads to -3,4-dihydroxythiolanes () exclusively in 67–89% yields. Desulfurization of by Raney nickel in ethanol affords either - or or -1,2-diols () in 51–82% yields.

  低价钛试剂在0°C下于四氢呋喃中的一系列二酮硫醚（）的分子内还原偶联反应仅产生67-89％的-3,4-二羟基硫杂环戊烷（）。阮内镍在乙醇中的脱硫产生-或-1,2-二醇（），产率为51-82％。
• Cyano and fluorodestannylation: A new methodology using some powerful sulfur transfer reagents, the organotin sulfides
  作者：David N. Harpp、Marc Gingras

  DOI：10.1016/s0040-4039(00)96513-4

  日期：1987.1

  Fluoride and cyanide ions destannylate bis(aralkyl)tin sulfides [R3SnSSnR3] and trialkyltin sulfides [R3SnSR′ (R = alkyl)] giving, in the presence of a variety of alkyl and activated halides, the corresponding thioether derivatives in excellent yield. The conditions are mild, neutral and anhydrous; a strong solvent effect is noted. Special comments are made concerning work-up procedures.

  氟化物和氰化物离子destannylate双（芳烷基）锡硫化物[R 3 SnSSnR 3 ]和三烷基锡硫化物[R 3 SnSR'（R =烷基）]给出，在多种烷基的存在和活化的卤化物，相应的硫醚衍生物，收率极高。条件温和，中性和无水；注意到强烈的溶剂作用。对后处理程序提出了特别的意见。
• Furfuryl propyl disulfide as a flavoring agent and methods for preparing and using same
  申请人：——

  公开号：US20020110628A1

  公开（公告）日：2002-08-15

  This invention pertains to a method for flavoring an ingestible composition with a flavoring agent, furfuryl propyl disulfide, in organoleptically purified form, unaccompanied by substances of natural origin present in cooked beef and onions. The flavoring agent may be used in a wide variety of ingestible vehicles to augment or enhance the aroma or taste of foodstuffs, particularly roasted nut, roasted meat, beef broth, black pepper, onion, fine herbs, omelet, and cooked onion omelet flavored foodstuffs. The present invention also pertains to an ingestible composition comprising an ingestible vehicle and an organoleptically effective amount of the purified flavoring agent. The present invention also pertains to furfuryl propyl disulfide represented by the formula, (2-Furan-CH 2 SSCH 2 CH 2 CH 3 ), in purified form, unaccompanied by substances of natural origin present in cooked beef and onions, and to methods for preparing furfuryl propyl disulfide.

  本发明涉及一种用味道剂味化可食用组合物的方法，所述味道剂为味觉上纯化的呋喃基丙基二硫化物，不含烹煮牛肉和洋葱时存在的天然物质。该味道剂可用于各种可食用载体中，以增强或提高食物的香气或口感，特别是烤坚果、烤肉、牛肉汤、黑胡椒、洋葱、香料、煎蛋和煮洋葱煎蛋调味食品。本发明还涉及一种包含可食用载体和纯化的味道剂的味道组合物。本发明还涉及用公式表示的呋喃基丙基二硫化物（2-呋喃-CH2SSCH2CH2CH3）的纯化形式，不含烹煮牛肉和洋葱时存在的天然物质，以及制备呋喃基丙基二硫化物的方法。
• Some Novel Meatlike Aroma Compounds from the Reactions of Alkanediones with Hydrogen Sulfide and Furanthiols
  作者：Donald S. Mottram、Marta S. Madruga、Frank B. Whitfield

  DOI：10.1021/jf00049a035

  日期：1995.1

  The products of reactions of hydrogen sulfide with 2,3-butanedione and with 2,3-pentanedione in dilute ethanolic solution were analyzed by CC-MS and CC-odor port analysis. Components were also collected from the GC column and analyzed by H-1 NMR. Mercaptoketones were formed which readily oxidized to the corresponding disulfides with traces of mono- and trisulfides. When 2-methyl-3-furanthiol or 2-furylmethanethiol was added to the reaction mixtures, a series of disulfides containing alkanone, 2-methyl-3-furyl and 2-furanmethyl moieties were formed. Some of these compounds have been found recently in the volatiles of cooked meat and in meatlike model systems. GC-odor port evaluation of the components of the reaction systems showed that disulfides containing the 2-methyl-3-furyl group had meaty aromas, whereas those without this group were sulfurous or onion-like in character.
• Schotte, Arkiv foer Kemi, 1953, vol. 5, p. 57,59
  作者：Schotte

  DOI：——

  日期：——