1,6-bis(4-hydroxyphenyl)hexane-1,6-dione | 20837-37-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,6-bis(4-hydroxyphenyl)hexane-1,6-dione
• 英文别名: 1.6-Bis-(4-hydroxy-phenyl)-hexandion-(1.6)；1,6-bis(4'-hydroxyphenyl)-1,6-hexanedione；1,6-Bis-(4-hydroxy-phenyl)-hexan-1,6-dion；1,6-Bis(4-hydroxyphenyl)-1,6-hexanedione
• CAS: 20837-37-0
• 化学式: C₁₈H₁₈O₄
• 分子量: 298.339
• InChiKey: ISNSMFRWEZSCRU-UHFFFAOYSA-N

物化性质

• 沸点：
  542.0±35.0 °C(Predicted)
• 密度：
  1.226±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,6-bis(4-hydroxyphenyl)hexane-1,6-dione 在 盐酸 、 amalgamated zinc 作用下， 生成 4-[6-(4-羟基苯基)己基]苯酚
  参考文献：
  名称：

  Dorn; Treibs, Chemische Berichte, 1955, vol. 88, p. 834,843

  摘要：

  DOI：
• 作为产物：
  描述：

  己二酸二苯酯 以 水 为溶剂， 生成 1,6-bis(4-hydroxyphenyl)hexane-1,6-dione
  参考文献：
  名称：

  Process for the preparation of bis-hydroxyphenyl-n-alkanes, new

  摘要：

  双羟基苯基-n-烷烃是通过将二羧酸或二羧酸衍生物与含氟有机磺酸接触制备的，必要时可以加入酚类化合物，并通过加氢将获得的烷二酮转化为双羟基苯基-n-烷烃，同时，必要时还可以进行额外的醚裂解。该发明还涉及新的双羟基苯基-n-烷烃和新的烷二酮。

  公开号：

  US04716252A1

文献信息

• Silylated polycarbonate polymers, method of making, and articles
  申请人：Lens Jan Pleun

  公开号：US20080306294A1

  公开（公告）日：2008-12-11

  A silylated dihydroxy aromatic compound of the formula (1a); wherein G a and G b are each independently C 1-12 alkyl, —OSi(C 1-12 alkyl) 3 , C 1-12 arylalkyl, or —OSi(C 1-12 arylalkyl) 3 ; Z a and Z b are each independently a straight or branched C 2-18 alkylene, a C 8-18 arylalkylene, or a C 8-18 alkylarylene, X a is a direct bond, a heteroatom-containing group, or a C 1-18 organic group, and r and s are each independently 1 or 2 is disclosed.

  一种具有式(1a)的硅烷化二羟基芳香族化合物；其中Ga和Gb各自独立地为C1-12烷基、—OSi(C1-12烷基)3、C1-12芳基烷基或—OSi(C1-12芳基烷基)3；Za和Zb各自独立地为直链或支链的C2-18亚烷基、C8-18芳基亚烷基或C8-18烷基芳基亚烷基，Xa为直接键、含杂原子基团或C1-18有机基团，且r和s各自独立地为1或2。
• Process for the preparation of bis-hydroxyphenyl-n-alkanes, new
  申请人：Bayer Aktiengesellschaft

  公开号：US04716252A1

  公开（公告）日：1987-12-29

  Bis-hydroxyphenyl-n-alkanes are prepared by contacting dicarboxylic acids or dicarboxylic acid derivatives with fluorine-containing organic sulphonic acids, where appropriate with the addition of a phenolic compound, and converting the alkanediones, which are thus obtainable, into bis-hydroxyphenyl-n-alkanes by hydrogenation and, where appropriate, an additional ether cleavage. The invention also relates to new bis-hydroxyphenyl-n-alkanes and to new alkanediones.

  双羟基苯基-n-烷烃是通过将二羧酸或二羧酸衍生物与含氟有机磺酸接触制备的，必要时可以加入酚类化合物，并通过加氢将获得的烷二酮转化为双羟基苯基-n-烷烃，同时，必要时还可以进行额外的醚裂解。该发明还涉及新的双羟基苯基-n-烷烃和新的烷二酮。
• [EN] METHODS OF MANUFACTURE OF 2-ARYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES<br/>[FR] PROCÉDÉS DE PRODUCTION DE 2-ARYL-3,3-BIS(HYDROXYARYL)PHTALIMIDINES
  申请人：SABIC GLOBAL TECHNOLOGIES BV

  公开号：WO2017182983A1

  公开（公告）日：2017-10-26

  A synthetic route for producing a 2-phenyl-3,3-bis(4-hydroxyphenyl)phthalimidine, using a dihydrophenolphthalein intermediate is provided. The dihydrophenolphthalein can be obtained by reduction of a precursor phenolphthalein that is commonly used in the manufacture of phthalimidines. Formation of the dihydrophenolphthalein is followed by activation, amide formation, and oxidation to provide the product phthalimidine

  提供了一种合成路线，用于生产2-苯基-3,3-双(4-羟基苯基)邻苯二酰亚胺，使用二氢苯酚邻苯二酮中间体。二氢苯酚邻苯二酮可以通过还原常用于制造邻苯二酰亚胺的前体苯酞酮获得。形成二氢苯酚邻苯二酮后，随后进行活化、酰胺形成和氧化以提供产物邻苯二酰亚胺。
• [EN] METHODS OF PURIFICATION OF 2-ARYL-3,3-BIS(4- HYDROXYARYL)PHTHALIMIDINES, AND POLYMERS DERIVED THEREFROM<br/>[FR] PROCÉDÉS DE PURIFICATION DE 2-ARYL-3,3-BIS(4- HYDROXYARYL)PHTHALIMIDINES ET DE SES POLYMÈRES DÉRIVÉS
  申请人：SABIC GLOBAL TECHNOLOGIES BV

  公开号：WO2018011702A1

  公开（公告）日：2018-01-18

  A method for the purification of a 2-aryl-3,3-bis(hydroxyaryl)phthalimidine including heating a reaction mixture comprising a phenolphthalein compound and a primary arylamine in the presence of an acid catalyst to form a reaction mixture comprising a 2-aryl-3,3- bis(hydroxyaryl)phthalimidine; quenching the reaction mixture with an aqueous alkali solution to form a quenched reaction mixture; extracting the quenched reaction mixture with an aminoaryl compound to form an organic layer and an extracted aqueous layer comprising a crude 2-aryl-3,3-bis(hydroxyaryl)phthalimidine is provided. Methods for the manufacture of a polycarbonate, including manufacturing the 2-aryl-3,3-bis(hydroxyaryl)phthalimidine, and polymerizing the 2-aryl-3,3-bis(hydroxyaryl)phthalimidine in the presence of a carbonate source are provided.

  提供了一种用于纯化2-芳基-3,3-双(羟基芳基)邻苯二酰亚胺的方法，包括在酸催化剂存在下加热反应混合物，该混合物包括邻苯二酚化合物和一种主要芳胺，以形成含有2-芳基-3,3-双(羟基芳基)邻苯二酰亚胺的反应混合物；用含水碱溶液淬灭反应混合物，形成淬灭后的反应混合物；用氨基芳基化合物萃取淬灭后的反应混合物，形成有机层和提取的含有粗2-芳基-3,3-双(羟基芳基)邻苯二酰亚胺的水层。还提供了一种聚碳酸酯的制备方法，包括制备2-芳基-3,3-双(羟基芳基)邻苯二酰亚胺，并在碳酸酯源存在下聚合2-芳基-3,3-双(羟基芳基)邻苯二酰亚胺。
• [EN] CONTINUOUS METHODS OF MANUFACTURE OF 2-ARYL-3,3-BIS(4-HYDROXYARYL)PHTHALIMIDINES, AND POLYMERS DERIVED THEREFROM<br/>[FR] PROCÉDÉS DE FABRICATION EN CONTINU DE 2-ARYL-3,3-BIS(4-HYDROXYARYL)PHTHALIMIDINES, ET DES POLYMÈRES DÉRIVÉS DE CELUI-CI
  申请人：SABIC GLOBAL TECHNOLOGIES BV

  公开号：WO2018013623A1

  公开（公告）日：2018-01-18

  A continuous method for the manufacture of a 2-aryl-3,3-bis(hydroxyaryl)phthalimidine comprising continuously heating an anhydride with a phenol in the presence of a catalyst and a first co-catalyst, to form a first reaction mixture comprising a phenolphthalein compound; precipitating the phenolphthalein compound; combining a primary arylamine with an acid catalyst and a second co-catalyst to form a second reaction mixture; adding the phenolphthalein compound to the second reaction mixture; continuously heating the second reaction mixture to provide a third reaction mixture comprising a crude phthalimidine; and treating the crude phthalimidine to remove aminophenol and purify the phthalimidine is provided.

  一种连续制备2-芳基-3,3-双(羟基芳基)邻苯二酰亚胺的方法，包括在催化剂和第一辅助催化剂的存在下，连续加热酐和酚，形成第一反应混合物，其中包括苯酚酞化合物；沉淀苯酚酞化合物；将一次芳基胺与酸性催化剂和第二辅助催化剂结合，形成第二反应混合物；将苯酚酞化合物加入第二反应混合物；连续加热第二反应混合物，得到包含粗邻苯二酰亚胺的第三反应混合物；并处理粗邻苯二酰亚胺以去除氨基酚并纯化邻苯二酰亚胺。