2-Brom-oenanthaldehyd-dimethylacetal | 18207-18-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Brom-oenanthaldehyd-dimethylacetal
• 英文别名: 2-bromo-1,1-dimethoxy-heptane；2-bromo-heptanal-dimethylacetal；2-Brom-oenanthol-dimethylacetal；2-Brom-heptanal-dimethylacetal；2-Bromo-1,1-dimethoxyheptane
• CAS: 18207-18-6
• 化学式: C₉H₁₉BrO₂
• 分子量: 239.153
• InChiKey: PMULERAPXGEXHE-UHFFFAOYSA-N

物化性质

• 沸点：
  117-119 °C(Press: 17 Torr)
• 密度：
  1.173±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-Brom-oenanthaldehyd-dimethylacetal 在 Amberlite IR-120 作用下， 生成 2-bromoheptanal
  参考文献：
  名称：

  Studies in Selectivity Aspects in the Synthesis of Aliphatic α-Bromoaldehydes

  摘要：

  A highly selective process scheme was developed to synthesize alpha-bromoaldehydes by regulating the important process parameters from a reaction-engineering point of view. Thus, alpha-bromobutyraldehyde and alpha-bromoheptaldehyde were synthesized in very high selectivity starting with butyraldehyde and heptaldehyde, In the bromination reaction at 40% conversion ratio, the selectivity was as high as 98% by using liquid bromine as the brominating agent.

  DOI：

  10.1021/op990025m
• 作为产物：
  描述：

  庚醛二甲基缩醛 在 溴 作用下， 以 二氯甲烷 为溶剂， 生成 2-Brom-oenanthaldehyd-dimethylacetal
  参考文献：
  名称：

  Studies in Selectivity Aspects in the Synthesis of Aliphatic α-Bromoaldehydes

  摘要：

  A highly selective process scheme was developed to synthesize alpha-bromoaldehydes by regulating the important process parameters from a reaction-engineering point of view. Thus, alpha-bromobutyraldehyde and alpha-bromoheptaldehyde were synthesized in very high selectivity starting with butyraldehyde and heptaldehyde, In the bromination reaction at 40% conversion ratio, the selectivity was as high as 98% by using liquid bromine as the brominating agent.

  DOI：

  10.1021/op990025m

文献信息

• �ber die Wirkungen von Aldehyden auf gesunde und maligne Zellen, 2. Mitt.: Synthese von homologen 4-Hydroxy-2-alkenalen, I
  作者：H. Esterbauer、W. Weger

  DOI：10.1007/bf01167149

  日期：——
• Preparation of α,β-Unsaturated Aldehyde Dimethyl Acetals and their Free Aldehydes
  作者：Paul Z. Bedoukian

  DOI：10.1021/ja01561a028

  日期：1957.2
• Bedoukian, Journal of the American Chemical Society, 1944, vol. 66, p. 1326
  作者：Bedoukian

  DOI：——

  日期：——
• Bedoukian, Organic Syntheses, Collective
  作者：Bedoukian

  DOI：——

  日期：——
• Studies in Selectivity Aspects in the Synthesis of Aliphatic α-Bromoaldehydes
  作者：Sudip Mukhopadhyay

  DOI：10.1021/op990025m

  日期：1999.11.1

  A highly selective process scheme was developed to synthesize alpha-bromoaldehydes by regulating the important process parameters from a reaction-engineering point of view. Thus, alpha-bromobutyraldehyde and alpha-bromoheptaldehyde were synthesized in very high selectivity starting with butyraldehyde and heptaldehyde, In the bromination reaction at 40% conversion ratio, the selectivity was as high as 98% by using liquid bromine as the brominating agent.