1-deoxy-L-talitol | 134002-88-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-deoxy-L-talitol
• 英文别名: (2S,3R,4S,5S)-Hexane-1,2,3,4,5-pentaol；(2S,3R,4S,5S)-hexane-1,2,3,4,5-pentol
• CAS: 134002-88-3
• 化学式: C₆H₁₄O₅
• 分子量: 166.174
• InChiKey: SKCKOFZKJLZSFA-OMMKOOBNSA-N

物化性质

• 沸点：
  468.0±40.0 °C(Predicted)
• 密度：
  1.424±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  101
• 氢给体数：
  5
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-deoxy-L-talitol 在 Enterobacter aerogenes IK₇ 作用下， 以 水 为溶剂， 生成 1-deoxy-L-tagatose
  参考文献：
  名称：

  Conversion of l-rhamnose into ten of the sixteen 1- and 6-deoxyketohexoses in water with three reagents: d-tagatose-3-epimerase equilibrates C3 epimers of deoxyketoses

  摘要：

  The efficient isomerization of L-rhamnose [the only cheaply available deoxy hexose] to 1-deoxy-L-psicose, 1-deoxy-D-psicose, 1-deoxy-L-fructose, 1-deoxy-D-fructose, 1-deoxy-L-tagatose, 6-deoxy-L-psicose, 6-deoxy-D-psicose, 6-deoxy-L-fructose, 6-deoxy-D-fructose, and 6-deoxy-L-tagatose is described. The conversion of rhamnose to ten of the sixteen 1- and 6-deoxyketohexoses is accomplished in water in three steps. The range of substrates for D-tagatose-3-epimerase (DTE) is extended to 1- and 6-deoxyketoses. An authentic sample of 6-deoxy-D-psicose is prepared from D-psicose. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.12.024
• 作为产物：
  描述：

  6-deoxy-L-psicose 在 氢气 作用下， 以 水 为溶剂， 50.0 ℃ 、1.2 MPa 条件下， 反应 8.0h， 以1.2 g的产率得到6-Desoxy-L-allit
  参考文献：
  名称：

  Conversion of l-rhamnose into ten of the sixteen 1- and 6-deoxyketohexoses in water with three reagents: d-tagatose-3-epimerase equilibrates C3 epimers of deoxyketoses

  摘要：

  The efficient isomerization of L-rhamnose [the only cheaply available deoxy hexose] to 1-deoxy-L-psicose, 1-deoxy-D-psicose, 1-deoxy-L-fructose, 1-deoxy-D-fructose, 1-deoxy-L-tagatose, 6-deoxy-L-psicose, 6-deoxy-D-psicose, 6-deoxy-L-fructose, 6-deoxy-D-fructose, and 6-deoxy-L-tagatose is described. The conversion of rhamnose to ten of the sixteen 1- and 6-deoxyketohexoses is accomplished in water in three steps. The range of substrates for D-tagatose-3-epimerase (DTE) is extended to 1- and 6-deoxyketoses. An authentic sample of 6-deoxy-D-psicose is prepared from D-psicose. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.12.024

文献信息

• DEOXYKETOHEXOSE ISOMERASE AND METHOD FOR PRODUCING DEOXYHEXOSE AND DERIVATIVE THEREOF USING SAME
  申请人：Izumori Ken

  公开号：US20100105885A1

  公开（公告）日：2010-04-29

  Providing 1- or 6-deoxy products corresponding to all of aldohexoses, ketohexoses and sugar alcohols, as based on Deoxy-Izumoring, as well as a method for systematically producing those products. A method for producing deoxyketohexose and a derivative thereof using a deoxyketohexose isomerase derived from Pseudomonas cichorii ST-24 (FERM BP-2736), comprising epimerizing 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose at position 3 to produce the individually corresponding 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose as an intended product.

  提供对应于所有己醛糖、己酮糖和糖醇的1-或6-去氧产物，基于去氧-Izumoring，以及一种系统生产这些产物的方法。一种使用来自Pseudomonas cichoriiST-24（FERM BP-2736）的去氧己酮糖异构酶生产去氧己酮糖及其衍生物的方法，包括将1-去氧D-己酮糖或6-去氧D-己酮糖或1-去氧L-己酮糖或6-去氧L-己酮糖在3号位置上对映异构化为各自对应的1-去氧D-己酮糖或6-去氧D-己酮糖或1-去氧L-己酮糖或6-去氧L-己酮糖作为预期产物。
• Effect of carbon chain length on catalytic C O bond cleavage of polyols over Rh-ReOx/ZrO2 in aqueous phase
  作者：Achraf Sadier、Noémie Perret、Denilson Da Silva Perez、Michèle Besson、Catherine Pinel

  DOI：10.1016/j.apcata.2019.117213

  日期：2019.9

  -tetraols, -triols, -diols, and hexanols) is achievable by hydrogenolysis of erythritol, xylitol, and sorbitol over supported-bimetallic Rh-ReOx (Re/Rh molar ratio 0.5) catalyst, respectively. After validation of the analytical methodology, the effect of some reaction parameters was studied. In addition to CO bond cleavage by hydrogenolysis, these polyols can undergo parallel reactions such as epimerization

  线性脱氧的C4（丁三醇，-二醇和丁醇），C5（戊四醇，-三醇，-二醇和戊醇）和C6产品（己烷五醇，-四醇，-三醇，-二醇和己醇）的生产可以实现赤藓糖醇，木糖醇和山梨糖醇分别在负载型双金属Rh-ReO x（Re / Rh摩尔比0.5）催化剂上进行氢解。在验证了分析方法之后，研究了一些反应参数的影响。除了通过氢解裂解C O键外，这些多元醇还可以进行平行反应，例如差向异构化，循环脱水和CC键裂解。线性脱氧C4，C5和C6产品每个家族的时间进程证实，不同类别的脱氧产品的出现顺序遵循多重顺序的脱氧途径。在高压下，在3.7wt。％Rh-3.5wt。％ReO x / ZrO 2催化剂存在下，对线性脱氧的C4，C5和C6产物混合物的最高选择性在80％的转化率下是有利的（54–71％ 80 bar下）在200°C下。
• DEOXYKETOHEXOSE ISOMERASE AND METHOD FOR PRODUCING DEOXYKETOHEXOSE AND DERIVATIVE THEREOF USING THE SAME
  申请人：National University Corporation Kagawa University

  公开号：EP2161332A1

  公开（公告）日：2010-03-10

  Providing 1- or 6-deoxy products corresponding to all of aldohexoses, ketohexoses and sugar alcohols, as based on Deoxy-Izumoring, as well as a method for systematically producing those products. A method for producing deoxyketohexose and a derivative thereof using a deoxyketohexose isomerase derived from Pseudomonas cichorii ST-24 (FERM BP-2736), comprising epimerizing 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose at position 3 to produce the individually corresponding 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose as an intended product.

  提供与所有醛己糖、酮己糖和糖醇相对应的1-或6-脱氧产品，如基于脱氧偶氮的产品，以及系统生产这些产品的方法。一种使用源自 Pseudomonas cichorii ST-24 的脱氧酮己糖异构酶（FERM BP-2736）生产脱氧酮己糖及其衍生物的方法、包括将1-脱氧D-酮己糖或6-脱氧D-酮己糖或1-脱氧L-酮己糖或6-脱氧L-酮己糖在位置3处外嵌，以产生单独对应的1-脱氧D-酮己糖或6-脱氧D-酮己糖或1-脱氧L-酮己糖或6-脱氧L-酮己糖作为目的产物。
• Methods for Generating Cardiomyocytes
  申请人：Srivastava Deepak

  公开号：US20130216503A1

  公开（公告）日：2013-08-22

  The present disclosure provides method of generating cardiomyocytes from post-natal fibroblasts. The present disclosure further provides cells and compositions for use in generating cardiomyocytes.
• US8389248B2
  申请人：——

  公开号：US8389248B2

  公开（公告）日：2013-03-05