4-[(2S,3S,4R,5R)-5-(3,4-dimethoxyphenyl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenol

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 呋喃类木脂素
• 英文名称: 4-[(2S,3S,4R,5R)-5-(3,4-dimethoxyphenyl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenol
• 化学式: C₂₁H₂₆O₅
• 分子量: 358.4
• InChiKey: YPQNDHHCUQGPFN-WVGOSAFVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• New platelet activating factor antagonists, named "the phomactins", their preparation and use
  申请人：Sankyo Company Limited

  公开号：EP0371762A2

  公开（公告）日：1990-06-06

  A series of new compounds, called "the phomactins" (I and II) is provided and may be isolated from the culture broth of fungi of the genus Phoma, especially Phoma sp. SANK 11486 (No. FERM BP-2598). These compounds are platelet activating factor antagonists and may be used for the treatment of disorders for which known such agents may also be used.

  本研究提供了一系列新化合物，称为 "噬菌体蛋白"（I 和 II），可从噬菌体属真菌，特别是噬菌体 sp. SANK 11486（编号 FERM BP-2598）的培养液中分离出来。这些化合物是血小板活化因子拮抗剂，可用于治疗已知此类药物也可用于治疗的疾病。
• COMPOSITION FOR IMPROVING PHYSICAL STRENGTH OR ATHLETIC ABILITY, CONTAINING NUTMEG EXTRACT AS ACTIVE INGREDIENT
  申请人：Korea Basic Science Institute

  公开号：EP3747452A1

  公开（公告）日：2020-12-09

  The present invention relates to a composition for improving physical strength or athletic ability, containing a nutmeg extract as an active ingredient and, more specifically, to a composition for improving physical strength or athletic ability, for treating sarcopenia, for improving muscle function, and for anti-fatigue, containing a nutmeg extract as an active ingredient. The nutmeg extract of the present invention contains a high quantity of ligand-based compounds and exhibits, when taken, very excellent effects of improving athletic ability, improving endurance and improving muscular strength, and thus is effective for treating sarcopenia and can be effectively used in medical supplies, food and the like for improving physical strength or athletic ability.

  本发明涉及一种含有肉豆蔻提取物作为活性成分的用于提高体力或运动能力的组合物，更具体地说，涉及一种含有肉豆蔻提取物作为活性成分的用于提高体力或运动能力、治疗肌肉疏松症、改善肌肉功能和抗疲劳的组合物。 本发明的肉豆蔻提取物含有大量配体基化合物，服用后在提高运动能力、提高耐力和提高肌肉力量方面有非常好的效果，因此可有效治疗肌肉疏松症，并可有效地用于医疗用品、食品等，以提高体力或运动能力。
• PHARMACEUTICAL GRADE BOTANICAL DRUGS
  申请人：Pharmaprint, Inc.

  公开号：EP0900375A1

  公开（公告）日：1999-03-10
• PHARMACEUTICAL GRADE GINKGO BILOBA
  申请人：Pharmaprint, Inc.

  公开号：EP1027603A2

  公开（公告）日：2000-08-16
• PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS
  申请人：Fundação de Amparo à Pesquisa do Estado de São Paulo - FAPESP

  公开号：EP1907380A2

  公开（公告）日：2008-04-09