(E)-2,6-dimethyl-6-octen-2-ol | 7643-66-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-2,6-dimethyl-6-octen-2-ol
• 英文别名: (E)-subaeneol；(E)-2,6-dimethyl-oct-6-en-2-ol；trans-2,6-Dimethyl-oct-6-en-2-ol；trans-2,6-Dimethyl-6-octen-2-ol；(E)-2,6-dimethyloct-6-en-2-ol
• CAS: 7643-66-5
• 化学式: C₁₀H₂₀O
• 分子量: 156.268
• InChiKey: CWMHVHGNKIXPOD-WEVVVXLNSA-N

物化性质

• 沸点：
  46-48 °C(Press: 0.4 Torr)
• 密度：
  0.8624 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  香叶基氯 在 lithium aluminium tetrahydride 、 mercury(II) diacetate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 6.6h， 生成 (E)-2,6-dimethyl-6-octen-2-ol
  参考文献：
  名称：

  摘要：

  Usinggas chromatography with flame ionization detection (FID) and electroantennographic detection (EAD) in parallel, butanoic acid, skatole, and (E)-2,6-dimethyl-6-octen-2-ol were identified as constituents of the abdominal sex-attracting secretion of the male dung beetle, Kheper subaeneus, which reproducibly elicited EAD responses in male and female antennae. This is the first report of the occurrence of (E)-2,6-dimethyl-6-octen-2-ol as a natural product, for which the name (E)-subaeneol is proposed. In some experiments, a few other constituents of the secretion also gave reproducible responses in specific male and female antennae but did not elicit responses when the analyses were repeated with other antennae. The major volatile constituent of the secretion, identified as (S)-(C)-2,6-dimethyl-5-heptenoic acid, is one of these EAD-active compounds. Both this compound and (E)-2,6-dimethyl-6-octen-2-ol were synthesized from authentic starting materials for comparison with the natural products.

  DOI：

  10.1023/a:1021440220329

文献信息

• FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS
  申请人：The Procter & Gamble Company

  公开号：US20160115424A1

  公开（公告）日：2016-04-28

  The present invention relates to a fragrance composition comprising ionic liquids for enhanced evaporation of the perfume raw materials. The invention also relates to methods of use of the fragrance compositions for perfuming suitable substrates, particularly skin and hair.

  本发明涉及一种包括离子液体的香精组合物，用于增强香料原料的蒸发。该发明还涉及使用这种香精组合物来为合适的基底，特别是皮肤和头发，进行香水处理的方法。
• Sesterterpene Compounds and Use Thereof
  申请人：Kang Heon Joong

  公开号：US20130274212A1

  公开（公告）日：2013-10-17

  The present invention relates to sesterterpene compounds, to the precursors thereof that are hydrolysable in a living body, or to the pharmaceutically acceptable salts thereof, and also relates to the prevention and treatment efficacy of the sesterterpene compounds with respect to non-insulin dependent diabetes mellitus, diabetic complications (renal failure and foot ulcers caused by diabetes), alcoholic, non-alcoholic, and viral fatty liver diseases, obesity, hyperlipidemia, atherosclerosis, cardiovascular diseases such as atherosclerotic stroke, and cerebropathies (Parkinsonism, schizophrenia and Alzheimer's disease). In addition, the present invention relates to compositions for functional foods, functional beverages, functional cosmetics, and functional feed.

  本发明涉及七萜化合物及其在生物体内可水解的前体物或其药学上可接受的盐，以及该七萜化合物在非胰岛素依赖性糖尿病、糖尿病并发症（由糖尿病引起的肾衰竭和足溃疡）、酒精性、非酒精性和病毒性脂肪肝疾病、肥胖症、高脂血症、动脉粥样硬化、动脉粥样硬化性中风、以及脑病（帕金森病、精神分裂症和阿尔茨海默病）的预防和治疗功效方面的应用。此外，本发明还涉及功能性食品、功能性饮料、功能性化妆品和功能性饲料的组合物。
• Solvolysis of 1,1-Dimethyl-4-Alkenyl Chlorides:  Evidence for π-Participation
  作者：Ivica Malnar、Sandra Jurić、Valerije Vrček、Željka Gjuranović、Zlatko Mihalić、Olga Kronja

  DOI：10.1021/jo0107608

  日期：2002.3.1

  cleaved C-Cl bond. The doubly unsaturated compound 3 (1,1-dimethyl-4,8-alkadienyl chloride) solvolyzes with further reduction of the isotope effect, and a drastically lower entropy of activation (k(H)/k(D) = 1.14 +/- 0.01; DeltaS(++) = -152 +/- 12 J mol(-1) K(-1), in 80% v/v aqueous ethanol), suggesting that the solvolysis of 3 proceeds by way of extended pi-participation, i.e., the assistance of both

  叔1,1-二甲基-4-链烯基氯（1）溶剂分解具有显着降低的次级β-氘动力学同位素效应（具有两个三氘甲基）的底物，并且其熵和活化焓低于参考的饱和类似物4（k（ H）/ k（D）= 1.30 +/- 0.03 vs k（H）/ k（D）= 1.79 +/- 0.01; Delta Delta H（++）= -9 kJ mol（-1），Delta Delta S （++）= -36 J mol（-1）K（-1），在80％v / v的乙醇水溶液中），表明双键参与了速率确定步骤。在理论上的MP2（fc）/ 6-31G（d）水平计算的过渡结构1-TS显示，该反应通过晚期过渡态进行，该过渡态具有明显的双键参与和基本上断裂的C-Cl键。双不饱和化合物3（1,1-二甲基-4，
• FRAGRANCE COMPOSITIONS AND USES THEREOF
  申请人：The Procter & Gamble Company

  公开号：EP3103431A1

  公开（公告）日：2016-12-14

  The present invention relates to a composition having improved or enhanced fidelity and/or longevity of the fragrance profile, comprising fragrance materials in a diamond construction and at least one substantially non-odorous fragrance modulator. The invention also relates to methods of use of the compositions for perfuming suitable substrates, including hard surfaces and body parts, particularly skin and hair.

  本发明涉及一种具有改进或增强的香味保真度和/或持久性的组合物，该组合物由钻石结构的香味材料和至少一种基本无臭的香味调节剂组成。本发明还涉及组合物的使用方法，用于对合适的基底（包括硬表面和身体部位，特别是皮肤和头发）进行加香。
• ABSORBENT ARTICLE COMPRISING FRAGRANCE COMPOSITION
  申请人：The Procter & Gamble Company

  公开号：EP3103523A1

  公开（公告）日：2016-12-14

  The present invention relates to a an absorbent article comprising a fragrance composition having improved or enhanced fidelity and/or longevity of the fragrance profile, comprising fragrance materials in a diamond construction and at least one substantially non-odorous fragrance modulator.

  本发明涉及一种由香味组合物组成的吸收制品，该香味组合物具有改进或增强的香味保真度和/或持久性，包括钻石结构的香味材料和至少一种基本无臭的香味调节剂。