6-O-(α-L-rhamnopyranosyl)-D-galactopyranose | 552-74-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-O-(α-L-rhamnopyranosyl)-D-galactopyranose
• 英文别名: O-α-L-rhamnopyranosyl-(1-6)-D-galactose；6-O-α-L-rhamnopyranosyl-D-galactose；Robinobiose；6-O-(6-Deoxy-I+/--L-mannopyranosyl)-D-galactopyranose；(3R,4S,5R,6R)-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol
• CAS: 552-74-9
• 化学式: C₁₂H₂₂O₁₀
• 分子量: 326.301
• InChiKey: OVVGHDNPYGTYIT-PDYCYQMRSA-N

物化性质

• 沸点：
  598.0±50.0 °C(Predicted)
• 密度：
  1.66±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  169
• 氢给体数：
  7
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  6-O-(α-L-rhamnopyranosyl)-D-galactopyranose 、 APTS 在 sodium cyanoborohydride 、 溶剂黄146 作用下， 以 四氢呋喃 为溶剂， 反应 20.0h， 生成
  参考文献：
  名称：

  Synthesis of fluorescently labelled rhamnosides: probes for the evaluation of rhamnogalacturonan II biosynthetic enzymes

  摘要：

  Three fluorescently labelled saccharides 10-12, representing structures found in pectic glycan rhamnogalacturonan II (RG-II), were synthesised by chemical glycosylation of O-6 of diacetone-D-galactose followed by deprotection and reductive amination with amino-substituted fluorophore APTS. This convenient method installs a common aminogalactitol-based tether in order to preserve the integrity of the reducing end of specific carbohydrates of interest. APTS-labelled glycans prepared in this manner were purified by carbohydrate gel electrophoresis and subjected to capillary electrophoresis analysis, as a basis for the subsequent development of high sensitivity assays for RG-II-active enzymes. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2011.03.039