2-Nitro-1-(2-phenyltriazol-4-yl)ethanol | 330855-59-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-Nitro-1-(2-phenyltriazol-4-yl)ethanol
• CAS: 330855-59-9
• 化学式: C₁₀H₁₀N₄O₃
• 分子量: 234.214
• InChiKey: CDAYIXWUSWBNET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  96.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-苯基-1,2,3-三唑-4-甲醛 、 硝基甲烷 在 3-methyl-4-[(2-phenyltriazol-4-yl)methylideneamino]-1H-1,2,4-triazole-5-thione 、 manganese(II) acetate 作用下， 以 乙醇 为溶剂， 以88%的产率得到2-Nitro-1-(2-phenyltriazol-4-yl)ethanol
  参考文献：
  名称：

  Mn(OAc)2/Schiff base as a new efficient catalyst system for the Henry reaction of nitroalkanes with aldehydes

  摘要：

  A series of novel Schiff bases bearing triazole structure were synthesized and characterized by IR and NMR. Mn(OAc)(2)/Schiff base efficiently catalyzed Henry reaction of nitroalkanes with aldehydes to produce the corresponding products of beta-nitroalcohols, under mild conditions with high yields (up to 99%). A reaction mechanism is proposed based on the experimental results. (C) 2012 Zheng Feng Xie. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2012.04.018

文献信息

• Mn(OAc)2/Schiff base as a new efficient catalyst system for the Henry reaction of nitroalkanes with aldehydes
  作者：Guang Peng Zhou、Yong Hai Hui、Ning Ning Wan、Qiu Ju Liu、Zheng Feng Xie、Ji De Wang

  DOI：10.1016/j.cclet.2012.04.018

  日期：2012.6

  A series of novel Schiff bases bearing triazole structure were synthesized and characterized by IR and NMR. Mn(OAc)(2)/Schiff base efficiently catalyzed Henry reaction of nitroalkanes with aldehydes to produce the corresponding products of beta-nitroalcohols, under mild conditions with high yields (up to 99%). A reaction mechanism is proposed based on the experimental results. (C) 2012 Zheng Feng Xie. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.