9,12,15,18-Tetraoxahexacosane | 180330-58-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 9,12,15,18-Tetraoxahexacosane
• 英文别名: 1-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]octane
• CAS: 180330-58-9
• 化学式: C₂₂H₄₆O₄
• 分子量: 374.605
• InChiKey: FTVMYCYPAGFMOX-UHFFFAOYSA-N

物化性质

• 沸点：
  441.1±25.0 °C(Predicted)
• 密度：
  0.898±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  26
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-氯辛烷 、 三乙二醇 在 二环己烷并-18-冠醚-6 、 氢氧化钾 作用下， 以 水 为溶剂， 反应 5.0h， 生成 9,12,15,18-Tetraoxahexacosane
  参考文献：
  名称：

  Tsarenko, N. A.; Yakshin, V. V.; Zhukova, N. G., Doklady Chemistry, 1981, vol. 258, p. 215 - 217

  摘要：

  DOI：

文献信息

• Process for the preparation of cyclic esters and method for purification of the same
  申请人：——

  公开号：US20030191326A1

  公开（公告）日：2003-10-09

  The present invention provides a process for production of a cyclic ester by depolymerization of an aliphatic polyester. In the process, a mixture containing the aliphatic polyester and a specific polyalkylene glycol ether, which has a boiling point of 230-450° C. and a molecular weight of 150-450, is heated under normal or reduced pressure to a temperature at which depolymerization of the aliphatic polyester takes place. Then, a substantially homogeneous solution phase, consisting of the melt phase of the aliphatic polyester and the liquid phase of the polyalkylene glycol ether, is formed. Heating of the solution phase is continued to form the cyclic ester by depolymerization and distil out the cyclic ester together with the polyalkylene glycol ether, and then the cyclic ester is recovered from the distillate. The present invention also provides a process for purification of a crude cyclic ester by use of the specific polyalkylene glycol ether described above.

  本发明提供了一种通过脂肪族聚酯的降解来生产环酯的方法。在该过程中，将含有脂肪族聚酯和具有沸点在230-450°C和分子量在150-450之间的特定聚烷基乙二醇醚的混合物，在常压或减压下加热至脂肪族聚酯发生降解的温度。然后，形成由脂肪族聚酯的熔融相和聚烷基乙二醇醚的液相组成的基本均相溶液相。继续加热溶液相以通过降解形成环酯并与聚烷基乙二醇醚一起蒸馏出环酯，然后从馏出物中回收环酯。本发明还提供了一种利用上述特定聚烷基乙二醇醚对粗环酯进行纯化的方法。
• METHOD FOR PRODUCING a-HYDROXYCARBOXYLIC ACID DIMERIC CYCLIC ESTER
  申请人：Kureha Corporation

  公开号：US20190330175A1

  公开（公告）日：2019-10-31

  Provided is a method for producing a high purity α-hydroxycarboxylic acid dimeric cyclic ester while heavy-component formation from an α-hydroxycarboxylic acid oligomer is suppressed. An α-hydroxycarboxylic acid dimeric cyclic ester is obtained by performing a depolymerization reaction in the coexistence of an inorganic acid or an inorganic acid salt or a mixture thereof; and an organophosphorus compound.

  提供了一种制备高纯度α-羟基羧酸二聚环酯的方法，同时抑制从α-羟基羧酸寡聚体中形成重组分。通过在无机酸或无机酸盐或二者混合物的共存下进行解聚反应，并加入有机磷化合物，可以得到α-羟基羧酸二聚环酯。
• METHOD FOR PRODUCING CYCLIC ESTER
  申请人：Kureha Corporation

  公开号：US20200392102A1

  公开（公告）日：2020-12-17

  In a method for producing a cyclic ester according to an embodiment of the present invention, a mixture (I) containing an aliphatic polyester, a specific polyalkylene glycol diether, and a sulfonic acid compound as a thermal stabilizer is prepared and heated in predetermined conditions to obtain a mixture (II) in a state of solution. Furthermore, heating of the mixture (II) is continued to distill, together with the polyalkylene glycol diether, a cyclic ester formed by the depolymerization reaction, and thus a distillate (III) is obtained. The cyclic ester is recovered from the distillate (III). At this time, a specific solubilizing agent is added to at least one of the mixture (I) or (II). In this production method, the sulfonic acid compound as the thermal stabilizer is contained in the mixtures (I) and (II) and the distillate (III).

  根据本发明实施例的一种制备环酯的方法中，制备含有脂肪族聚酯、特定聚烷基醚二醇和磺酸化合物作为热稳定剂的混合物(I)，并在预定条件下加热，得到处于溶液状态的混合物(II)。此外，继续加热混合物(II)以蒸馏，与聚烷基醚二醇一起蒸馏出由去聚合反应形成的环酯，从而得到馏出物(III)。从馏出物(III)中回收环酯。此时，在混合物(I)或(II)中至少添加一种特定的溶解剂。在此生产方法中，磺酸化合物作为热稳定剂被包含在混合物(I)、(II)和馏出物(III)中。
• METHOD FOR PURIFYING TETRAKIS(FLUOROARYL) BORATE/MAGNESIUM HALIDE, TETRAKIS(FLUOROARYL) BORATE/ETHER COMPLEX AND PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PREPARING TETRAKIS(FLUOROARYL) BORATE DERIVATIVE
  申请人：Nippon Shokubai Co., Ltd.

  公开号：EP0913400A1

  公开（公告）日：1999-05-06

  A method for purifying Ar4 BMgX which comprises treating a tetrakis(fluoroaryl) borate/magnesium halide (Ar4BMgX) with (1) an alkaline (earth) metal salt of carboxylic acid, (2) an acid, (3) an acid and then an alkaline (earth) metal hydroxide, or (4) an acid and then an alkaline (earth) metal salt of carboxylic acid; and a process for preparing a tetrakis(fluoroaryl) borate derivative (Ar4BZ) which comprises reacting the treated Ar4BMgX with a compound capable of generating monovalent cationic species. The above purification method permits separation and removal of impurities contained in Ar4 BMgX in an efficient and simple manner. The invention also provides a tetrakis(fluoroaryl) borate/ether complex, a process for preparing the same, and a process for preparing a tetrakis(fluoroaryl) borate derivative (Ar4BZ) by using the ether complex and the compound capable of generating monovalent cationic species as starting compounds. The ether complex can be easily purified to a high purity and hence is suitable as an intermediate for the preparation of various tetrakis(fluoroaryl) borate derivatives.

  一种提纯 Ar4 BMgX 的方法，包括用(1)羧酸的碱(土)金属盐、(2)酸、(3)酸然后碱(土)金属氢氧化物或(4)酸然后羧酸的碱(土)金属盐处理四(氟芳基)硼酸盐/卤化镁(Ar4BMgX)；以及制备四（氟芳基）硼酸酯衍生物（Ar4BZ）的工艺，包括将处理过的 Ar4BMgX 与能够生成一价阳离子物种的化合物反应。上述纯化方法可以高效、简单地分离和去除 Ar4 BMgX 中所含的杂质。本发明还提供了一种四(氟芳基)硼酸酯/醚络合物、制备四(氟芳基)硼酸酯/醚络合物的工艺，以及以醚络合物和能够生成一价阳离子种类的化合物为起始化合物制备四(氟芳基)硼酸酯衍生物(Ar4BZ)的工艺。醚络合物很容易提纯到高纯度，因此适合用作制备各种四（氟芳基）硼酸酯衍生物的中间体。
• PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME
  申请人：KUREHA KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP1310496A1

  公开（公告）日：2003-05-14

  The present invention provides a process for production of a cyclic ester by depolymerization of an aliphatic polyester. In the process, a mixture containing the aliphatic polyester and a specific polyalkylene glycol ether, which has a boiling point of 230-450°C and a molecular weight of 150-450, is heated under normal or reduced pressure to a temperature at which depolymerization of the aliphatic polyester takes place. Then, a substantially homogeneous solution phase, consisting of the melt phase of the aliphatic polyester and the liquid phase of the polyalkylene glycol ether, is formed. Heating of the solution phase is continued to form the cyclic ester by depolymerization and distil out the cyclic ester together with the polyalkylene glycol ether, and then the cyclic ester is recovered from the distillate. The present invention also provides a process for purification of a crude cyclic ester by use of the specific polyalkylene glycol ether described above.

  本发明提供了一种通过脂肪族聚酯解聚生产环酯的工艺。在该工艺中，将含有脂肪族聚酯和特定聚亚烷基乙二醇醚（沸点为 230-450°C，分子量为 150-450）的混合物在常压或减压下加热至脂肪族聚酯发生解聚的温度。然后形成基本均匀的溶液相，该溶液相由脂肪族聚酯的熔体相和聚亚烷基二醇醚的液相组成。继续加热溶液相，通过解聚作用形成环酯，并将环酯和聚烷基乙二醇醚一起蒸馏出来，然后从蒸馏物中回收环酯。本发明还提供了一种通过使用上述特定聚亚烷基二醇醚提纯粗环酯的工艺。