(Z)-2-fluoro-n-oct-2-en-1-ol | 55371-41-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: (Z)-2-fluoro-n-oct-2-en-1-ol
• 英文别名: (Z)-2-fluoro-oct-2-en-1-ol；(Z)-2-fluorooct-2-en-1-ol
• CAS: 55371-41-0
• 化学式: C₈H₁₅FO
• 分子量: 146.205
• InChiKey: ICNHNHOFDHORMG-VURMDHGXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (Z)-2-fluoro-n-oct-2-en-1-ol 在 4% Pd/C 、 氢气 作用下， 以 甲醇 为溶剂， 反应 2.0h， 生成 2-fluoro-1-octanol
  参考文献：
  名称：

  Enantioselective bioreduction of 2-fluoro-2-alken-1-ols mediated by Saccharomyces cerevisiae

  摘要：

  Biocatalytic reduction of 2-fluoro-2-alken-1-ols mediated by Saccharomyces cerevisiae underwent smoothly and yielded (S)-2-fluorinated alkanols with high enantioselectivities. The conversion rate was markedly depending on the configuration of alkene moiety of the substrate, the chain length of alkyl group at beta position of C=C bond, as well as the reaction conditions. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcatb.2011.02.011
• 作为产物：
  描述：

  己酰氯 在 sodium tetrahydroborate 、 正丁基锂 、 二异丁基氢化铝 作用下， 以 四氢呋喃 、 乙醇 、 正己烷 为溶剂， 反应 9.0h， 生成 (Z)-2-fluoro-n-oct-2-en-1-ol
  参考文献：
  名称：

  Enantioselective bioreduction of 2-fluoro-2-alken-1-ols mediated by Saccharomyces cerevisiae

  摘要：

  Biocatalytic reduction of 2-fluoro-2-alken-1-ols mediated by Saccharomyces cerevisiae underwent smoothly and yielded (S)-2-fluorinated alkanols with high enantioselectivities. The conversion rate was markedly depending on the configuration of alkene moiety of the substrate, the chain length of alkyl group at beta position of C=C bond, as well as the reaction conditions. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcatb.2011.02.011

文献信息

• Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites
  申请人：American Cyanamid Company

  公开号：EP0933027A1

  公开（公告）日：1999-08-04

  The present invention relates to methods and compositions for treating animals and humans, and for controlling, preventing and protecting animals and humans from infestation and infection by arthropod and helminth parasites by administering or applying to the animals, humans or their environment a 1,4-diaryl-2-fluoro-2-butene or 1,4-diaryl-2,3-difluoro-2-butene compound having the structural formula

  本发明涉及用于治疗动物和人类、控制、预防和保护动物和人类免受节肢动物和蠕虫寄生虫侵染和感染的方法和组合物，通过向动物、人类或其环境施用具有结构式的1,4-二芳基-2-氟-2-丁烯或1,4-二芳基-2,3-二氟-2-丁烯化合物。
• Allylic Hydroxylation of Vinyl Fluorides
  作者：Thomas Ernet、Günter Haufe

  DOI：10.1055/s-1997-1279

  日期：1997.8

  Terminal and non-terminal vinyl fluorides have been hydroxylated regioselectively in the allylic position adjacent to the fluorine bearing carbon using selenium dioxide and tert-butyl hydroperoxide.

  使用二氧化硒和叔丁基过氧化氢，在邻近含氟碳的烯丙基位置对末端和非末端乙烯基氟化物进行区域选择性羟基化。
• 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents
  申请人：American Cyanamid Company

  公开号：EP0811593A1

  公开（公告）日：1997-12-10

  Pesticidal 1,4-diaryl-2-fluoro-2-butene compounds having the structural formula I and compositions and methods comprising those compounds for the control of insect and acarid pests.

  具有结构式 I 的 1,4-二芳基-2-氟-2-丁烯杀虫化合物 以及包含这些化合物的用于控制昆虫和害虫的组合物和方法。
• Shahak,I. et al., Israel Journal of Chemistry, 1974, vol. 12, p. 749 - 755
  作者：Shahak,I. et al.

  DOI：——

  日期：——
• US5849958A
  申请人：——

  公开号：US5849958A

  公开（公告）日：1998-12-15