4,5-dichloro-2-(3,4-dichlorophenyl)-pyrrole-3-carbonitrile | 122452-95-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 4,5-dichloro-2-(3,4-dichlorophenyl)-pyrrole-3-carbonitrile
• 英文别名: 4,5-dichloro-2-(3, 4-dichlorophenyl)pyrrole-3-carbonitrile；4,5-dichloro-2-(3,4-dichlorophenyl)pyrrole-3-carbonitrile；4,5-dichloro-2-(3,4-dichlorophenyl)-1H-pyrrole-3-carbonitrile
• CAS: 122452-95-3
• 化学式: C₁₁H₄Cl₄N₂
• 分子量: 305.978
• InChiKey: GWDQLAOKLMLQSJ-UHFFFAOYSA-N

物化性质

• 熔点：
  >235 °C
• 沸点：
  497.3±45.0 °C(Predicted)
• 密度：
  1.66±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  39.6
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4,5-dichloro-2-(3,4-dichlorophenyl)-pyrrole-3-carbonitrile 在 potassium tert-butylate 、 碘甲烷 作用下， 以 四氢呋喃 、 水 、 乙酸乙酯 为溶剂， 以86%的产率得到4,5-Dichloro-2-(3,4-dichlorophenyl)-1-methyl-pyrrole-3-carbonitrile
  参考文献：
  名称：

  Method of controlling phytopathogenic fungi

  摘要：

  这项发明涉及一种通过将氰基或硝基芳基吡咯烷化合物与植物病原真菌接触，或将该吡咯烷化合物应用于易受该病原菌引起疾病的植物叶面来控制植物病原真菌的方法。

  公开号：

  EP0358047A3
• 作为产物：
  描述：

  5-bromo-2-(3,4-dichlorophenyl)pyrrole-3-carbonitrile 在 磺酰氯 作用下， 以 正庚烷 、 溶剂黄146 为溶剂， 生成 4,5-dichloro-2-(3,4-dichlorophenyl)-pyrrole-3-carbonitrile
  参考文献：
  名称：

  Debrominative chlorination of pyrroles

  摘要：

  提供了一种简单的定量程序，用于通过在吡咯环上用氯代替溴，氯化含有电子吸引基团的吡咯化合物。

  公开号：

  US05563279A1

文献信息

• Method of and bait compositions for controlling mollusks
  申请人：American Cyanamid Company

  公开号：US04929634A1

  公开（公告）日：1990-05-29

  This invention relates to methods of controlling mollusks with arylpyrrole compounds and to bait compositions containing a molluscicidally effective amount of an arylpyrrole compound.

  这项发明涉及使用芳基吡咯烷化合物控制软体动物的方法，以及含有对软体动物具有杀鲜效果的芳基吡咯烷化合物的诱饵组合物。
• Arylpyrrole insecticidal acaricidal and nematicidal agents and methods
  申请人：American Cyanamid Company

  公开号：US05010098A1

  公开（公告）日：1991-04-23

  This invention is directed to certain novel insecticidal, acaricidal and nematicidal arylpyrrole agents and a method for controlling insects, acarids and nematodes therewith. The invention also is directed to a method for protecting growing plants from insect, acarid and nematode attack by applying to said plants or the soil in which they are growing, an insecticidally, acaricidally or nematicidally effective amount of a novel arylpyrrole compound. The present invention further is directed to a method for the preparation of the arylpyrrole compounds.

  该发明涉及一种新型的杀虫、杀螨和杀线虫的芳基吡咯烷类药剂，以及一种通过使用这些药剂来控制昆虫、螨虫和线虫的方法。该发明还涉及一种通过向生长中的植物或其生长的土壤施加一定量的新型芳基吡咯烷类化合物来保护植物免受昆虫、螨虫和线虫侵害的方法。本发明还涉及一种制备芳基吡咯烷类化合物的方法。
• Insecticidal and synergistic miticidal compositions
  申请人：American Cyanamid Company

  公开号：US05187184A1

  公开（公告）日：1993-02-16

  This invention relates to new insecticidal and synergistic miticidal compositions containing as essential active ingredients an arylpyrrolecarbonitrile or arylnitropyrrole and an arylpyrazolecarboxamide. The invention also relates to a method for protecting growing plants from infestation and attack by insects and plant mites comprising applying to the foliage and stems of said plants an insecticidally and miticidally effective amount of a composition containing a synergistic mixture of an arylpyrrolecarbonitrile or arylnitropyrrole and an arylpyrazolecarboxamide dispersed in an inert diluent, or sequentially applying to the foliage and stems of plants which are to be protected from attack by insects and plant mites, an arylpyrazolecarboxamide and a synergistically effective amount of an arylnitropyrrole or arylpyrrolecarbonitrile.

  本发明涉及一种新的杀虫剂和协同杀螨剂组合物，其包含芳基吡咯烷腈或芳基硝基吡咯和芳基吡唑羧酰胺作为必需的活性成分。本发明还涉及一种保护植物不受昆虫和植物螨侵害和攻击的方法，包括向所述植物的叶片和茎部施用含有芳基吡咯烷腈或芳基硝基吡咯和芳基吡唑羧酰胺协同混合物的杀虫和杀螨有效量的组合物，分散在惰性稀释剂中，或者按顺序向将要受到昆虫和植物螨攻击的植物的叶片和茎部施用芳基吡唑羧酰胺和芳基硝基吡咯或芳基吡咯烷腈的协同有效量。
• N-alkanoylaminomethyl and N-aroylaminomethyl pyrrole insecticidal and
  申请人：American Cyanamid Company

  公开号：US05130328A1

  公开（公告）日：1992-07-14

  This invention relates to N-alkanoylaminomethyl and N-aroylaminomethyl pyrrole compounds. It also relates to the use of said compounds as insecticidal and acaricidal agents and to a method of protecting plants from attack by insects and acarina by application of an N-alkanoylaminomethyl or N-aroylaminomethyl pyrrole to said plants or to the locus in which they are growing.

  本发明涉及N-烷酰胺基甲基和N-芳酰胺基甲基吡咯化合物。它还涉及将上述化合物用作杀虫和杀螨剂的用途，并通过将N-烷酰胺基甲基或N-芳酰胺基甲基吡咯应用于植物或它们生长的位置，来保护植物免受昆虫和螨的攻击的方法。
• Methods for the control and the protection of warm-blooded animals
  申请人：American Cyanamid Company

  公开号：US05455263A1

  公开（公告）日：1995-10-03

  This invention relates to methods controlling, and protecting warm-blooded animals from infestation and infection by helminths, acarids and arthropod endo- and ectoparasites by administering or applying to the animals a substituted arylpyrrole compound.

  本发明涉及一种方法，通过给动物施用或涂抹一种取代芳基吡咯化合物，控制和保护温血动物免受蠕虫、螨和节肢动物内外寄生虫的侵染和感染。