Austrobailignan-7 | 55890-25-0

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 呋喃类木脂素
• 英文名称: Austrobailignan-7
• 英文别名: Austrobailignan 7；4-[(2R,3S,4S,5S)-5-(1,3-benzodioxol-5-yl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenol
• CAS: 55890-25-0
• 化学式: C₂₀H₂₂O₅
• 分子量: 342.392
• InChiKey: JPDORDSJPIKURD-UAFHBQARSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• NOVEL USE OF LIGNAN-TYPE COMPOUNDS OR EXTRACT OF NUTMEG OR ARIL OF NUTMEG COMPRISING THE SAME
  申请人：Hwang Jae Kwan

  公开号：US20110118346A1

  公开（公告）日：2011-05-19

  The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.
• USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT
  申请人：Hwang Jae-Kwan

  公开号：US20120288579A1

  公开（公告）日：2012-11-15

  The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme-1 (MMP-1, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.
• US8435957B2
  申请人：——

  公开号：US8435957B2

  公开（公告）日：2013-05-07
• US8969408B2
  申请人：——

  公开号：US8969408B2

  公开（公告）日：2015-03-03