Influence of Zwitterions on Thermomechanical Properties and Morphology of Acrylic Copolymers: Implications for Electroactive Applications
摘要:
n-Butyl acrylate-based zwitterionomers and ionomers containing 3-[[2-(methacryloyloxy)ethyn(dimethypammonio]-1-propanesulfonate (SBMA) and 2-[butyl(dimethyl)amino]ethyl methacrylate methanesulfonate (BDMAEMA MS), respectively, were synthesized using conventional free radical polymerization. Size-exclusion chromatography confirmed the molecular weights of the copolymers exceeded the critical molecular weight between entanglements (Me) for poly(n-butyl acrylate). Differential scanning calorimetry (DSC), small-angle X-ray scattering (SAXS), and atomic force microscopy (AFM) revealed that zwitterionomers promoted more well-defined microphase separation than cationic analogues. Dynamic mechanical analyses (DMA) of the copolymers showed a rubbery plateau region due to physical cross-links between charges for zwitterionomers only. Since SBMA and BDMAEMA MS have very similar chemical structures, we attributed improved microphase separation and superior elastomeric performance of the zwitterionomers to stronger association between covalently tethered charged pairs.
[EN] THERAPEUTIC ACRYLATES AS ENHANCED MEDICAL ADHESIVES<br/>[FR] ACRYLATES THÉRAPEUTIQUES UTILES EN TANT QU'ADHÉSIFS MÉDICAUX AMÉLIORÉS
申请人:UNIV CARNEGIE MELLON
公开号:WO2018052936A1
公开(公告)日:2018-03-22
Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone cement also are provided along with uses for the compositions.
In accordance with aspects of the invention methods of using rhodium hydroquinone catalysts for the conjugate addition of boronic acids are disclosed.
根据发明的某些方面,公开了使用铑对苯二酚催化剂进行硼酸偶联加成的方法。
Rhodium quinonoid catalysts
申请人:Sweigart A. Dwight
公开号:US20070117981A1
公开(公告)日:2007-05-24
In accordance with one aspect of the invention a rhodium quinonoid catalyst is disclosed.
根据发明的某一方面,公开了一种铑醌类催化剂。
Fused quinonic compounds
申请人:Centro Atlantico del Medicamento S.A (Ceamed, S.A)
公开号:EP2690094A1
公开(公告)日:2014-01-29
A compound having the formula (I):
for use in treating disease; a composition comprising said fused quinonic compound of formula (I) and at least one pharmaceutically acceptable carrier; as well as a method of modulating a Janus Kinase-Signal Transduction and Activators of Transcription (JAK-STAT) pathway. The activation of a JAK-STAT pathway is associated with several disease states such as immunological and inflammatory diseases, hyperproliferative disorders including cancer, and myeloproliferative diseases.
METHOD OF PREPARATION OF STEREOSPECIFIC QUINONE DERIVATIVES
申请人:Mehta Dilip S.
公开号:US20150126763A1
公开(公告)日:2015-05-07
The description provides processes for the regio and stereospecific synthesis of polyprenylatedquinone derivatives, such as Vitamin K1, K2 and Ubiquinone, exploiting dithioacetals, especially 1,3-dithiane, mediated Umpolung chemistry which works along a new concept “Inhibiting resonance delocalization (IRD)” to overcome isomerization generated due to delocalization of allyliccarbanion on the π-electron cloud of an allylic systems by the conventional synthesis.