2-脱氧-4-酮-D-核糖 | 55601-42-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-脱氧-4-酮-D-核糖
• 英文名称: 2-deoxy-4-keto-D-ribose
• 英文别名: (3S)-3,5-Dihydroxy-4-oxopentanal；(3S)-3,5-dihydroxy-4-oxopentanal
• CAS: 55601-42-8
• 化学式: C₅H₈O₄
• 分子量: 132.116
• InChiKey: ABHWXAPFZLYHJU-BYPYZUCNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-脱氧-D-核糖 在 Gluconobacter oxydans NBRC 12528 membrane fraction 作用下， 反应 8.0h， 生成 2-deoxy-D-pent-4-ulosonic acid 、 2-脱氧-4-酮-D-核糖
  参考文献：
  名称：

  Pentose Oxidation by Acetic Acid Bacteria Led to a Finding of Membrane-Bound Purine Nucleosidase

  摘要：

  D-Ribose and 2-deoxy-D-ribose were oxidized to 4-keto-D-ribonate and 2-deoxy-4-keto-D-ribonate respectively by oxidative fermentation, and the chemical structures of the oxidation products were confirmed to be as expected. Both pentoses are important sugar components of nucleic acids. When examined, purine nucleosidase activity predominated in the membrane fraction of acetic acid bacteria. This is perhaps the first finding of membrane-bound purine nucleosidase.

  DOI：

  10.1271/bbb.130066

文献信息

• Pentose Oxidation by Acetic Acid Bacteria Led to a Finding of Membrane-Bound Purine Nucleosidase
  作者：Osao ADACHI、Roque A. HOURS、Yoshihiko AKAKABE、Emiko SHINAGAWA、Yoshitaka ANO、Toshiharu YAKUSHI、Kazunobu MATSUSHITA

  DOI：10.1271/bbb.130066

  日期：2013.5.23

  D-Ribose and 2-deoxy-D-ribose were oxidized to 4-keto-D-ribonate and 2-deoxy-4-keto-D-ribonate respectively by oxidative fermentation, and the chemical structures of the oxidation products were confirmed to be as expected. Both pentoses are important sugar components of nucleic acids. When examined, purine nucleosidase activity predominated in the membrane fraction of acetic acid bacteria. This is perhaps the first finding of membrane-bound purine nucleosidase.