9-(hydroxymethyl)-2,3-benzo-14-crown-4 | 107094-23-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 9-(hydroxymethyl)-2,3-benzo-14-crown-4
• 英文别名: 2-hydroxymethylbenzo-14-crown-4；hydroxymethyl-benzo-14-crown-4；2,6,9,13-Tetraoxabicyclo[12.4.0]octadeca-1(18),14,16-trien-7-ylmethanol
• CAS: 107094-23-5
• 化学式: C₁₅H₂₂O₅
• 分子量: 282.337
• InChiKey: CPLHOISJOWOWCE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  二氯代磷酸丁酯 、 9-(hydroxymethyl)-2,3-benzo-14-crown-4 生成 Butyl 2,6,9,13-tetraoxabicyclo[12.4.0]octadeca-1(18),14,16-trien-7-ylmethyl hydrogen phosphate
  参考文献：
  名称：

  Highly selective lithium ion transport and extraction with crowned alkyl phosphoric acid

  摘要：

  A series of benzo-14-crown-4 derivatives (3a-3c) having an ionizable alkyl phosphoric acid moiety as an additional binding site were synthesized. From the results of transport and extraction experiments, it is revealed that 3c exhibited a drastic enhancement in Li+ ion transport rate and extractability when compared with the corresponding hydroxymethyl derivative.

  DOI：

  10.1016/0040-4039(92)89039-f
• 作为产物：
  描述：

  o-bis((3-chloropropyl)oxy)benzene 在 palladium on activated charcoal 氢气 、 对甲苯磺酸 、 lithium bromide 、 lithium tert-butoxide 作用下， 以 乙醇 、 水 、 叔丁醇 为溶剂， 反应 360.0h， 生成 9-(hydroxymethyl)-2,3-benzo-14-crown-4
  参考文献：
  名称：

  Czech, Bronislaw P.; Czech, Anna; Son, Byungki, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 465 - 471

  摘要：

  DOI：

文献信息

• Highly selective lithium ion transport and extraction with crowned alkyl phosphoric acid
  作者：Yoichi Habata、Sadatoshi Akabori

  DOI：10.1016/0040-4039(92)89039-f

  日期：1992.9

  A series of benzo-14-crown-4 derivatives (3a-3c) having an ionizable alkyl phosphoric acid moiety as an additional binding site were synthesized. From the results of transport and extraction experiments, it is revealed that 3c exhibited a drastic enhancement in Li+ ion transport rate and extractability when compared with the corresponding hydroxymethyl derivative.
• Czech, Bronislaw P.; Czech, Anna; Son, Byungki, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 465 - 471
  作者：Czech, Bronislaw P.、Czech, Anna、Son, Byungki、Lee, Han Koo、Bartsch, Richard A.

  DOI：——

  日期：——
• Habata, Yoichi; Ikeda, Manami; Akabori, Sadatoshi, Journal of the Chemical Society. Perkin transactions I, 1992, # 20, p. 2651 - 2656
  作者：Habata, Yoichi、Ikeda, Manami、Akabori, Sadatoshi

  DOI：——

  日期：——