3,3,4,4,5,5,5-七氟-2-甲基-2-戊醇 | 355-22-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 3,3,4,4,5,5,5-七氟-2-甲基-2-戊醇
• 英文名称: 1,1,1,2,2,3,3-heptafluoro-4-methylpentan-4-ol
• 英文别名: (perfluoro n-propyl) dimethyl methanol；3,3,4,4,5,5,5-heptafluoro-2-methyl-pentan-2-ol；3,3,4,4,5,5,5-Heptafluor-2-methyl-pentan-2-ol；2-Methyl-3,3,4,4,5,5,5-heptafluor-pentan-2-ol；3,3,4,4,5,5,5-Heptafluoro-2-methyl-2-pentanol；3,3,4,4,5,5,5-heptafluoro-2-methylpentan-2-ol
• CAS: 355-22-6
• 化学式: C₆H₇F₇O
• 分子量: 228.11
• InChiKey: CZPWXOSMOFCBOR-UHFFFAOYSA-N

物化性质

• 沸点：
  108 °C
• 密度：
  1.439 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  8

安全信息

• 海关编码：
  2905590090

反应信息

• 作为反应物：
  描述：

  3,3,4,4,5,5,5-七氟-2-甲基-2-戊醇 在 四氯化碳 、 氯 作用下， 生成 1-chloro-3,3,4,4,5,5,5-heptafluoro-2-methyl-pentan-2-ol
  参考文献：
  名称：

  Chlorination of Fluorine—containing Alcohols¹

  摘要：

  DOI：

  10.1021/ja01103a027
• 作为产物：
  描述：

  甲基溴化镁 、 七氟丁酸酐 在 乙醚 作用下， 生成 3,3,4,4,5,5,5-七氟-2-甲基-2-戊醇
  参考文献：
  名称：

  Fluorinated Paraffins

  摘要：

  DOI：

  10.1021/jo01093a022

文献信息

• Estimation of hydrocarbon solubilities in hydrofluorocarbons
  作者：Michael Van Der Puy、Andrew J. Poss、Phillip J. Persichini、Lois A.S. Ellis

  DOI：10.1016/0022-1139(93)02960-m

  日期：1994.6

  A new solubility parameter, SP, for hydrofluorocarbons (HFCs) has been developed (SP=1.175 ln(np)+ 0.025H-0.063F-0.028α-0.018β where np depends on the molar volume and the molar refractivity; H and F are the number of hydrogens and fluorines, respectively, in the molecule; and α and β are the respective numbers of H-C-F and H-C-C-F connections). Values of SP have been used to predict if an HFC would

  已经开发出用于氢氟碳化合物（HFC）的新溶解度参数SP（SP = 1.175 ln（np）+ 0.025 H -0.063 F -0.028α-0.018β，其中np取决于摩尔体积和摩尔折射率；H和F分别是分子中氢和氟的数目；而α和β分别是HCF和HCCF连接的数目。SP的价值HFC已被用来预测HFC在25°C下对于各种碳氢化合物是否是良好的溶剂。在异构HFC族中，对烃具有最大溶解能力的单个HFC是那些氟与氢的分离度最大的HFC。将希尔德布兰德溶解度参数δ与半经验SP值进行比较。
• Studies on Grignard reagents. Part I. Fluorine nuclear magnetic resonance spectra of fluoroaryl Grignard reagents
  作者：D. F. Evans、M. S. Khan

  DOI：10.1039/j19670001643

  日期：——

  1·0; C6F5MgCl, 2·0; C6F5Mgl, 1·4; 3-F,5,4Cl2C6H2·MgBr, ca. 2·5; C10H6FMgl, 20; p-F·C6H4·MgBr, 20; p-F·C6H4·Mgl 20. Limited additional information concerning the nature of these “RMgX” and “R2Mg” species has been obtained from the fluorine chemical shifts. The rates of fluoroaryl exchange qualitatively follow the sequence C6F5Mgl < C6F5MgBr < C6F5MgCl C10H6FMgl < C6H2Cl2FMgBr < p-F·C6H4·Mgl < p-F·C6H4·MgBr

  已在一定温度范围内测量了氟代芳基格氏试剂，相应的双芳基镁以及两者的混合物的氟共振光谱。因此，有可能减慢氟芳基交换并明确区分“ RMgX”和“ R 2 Mg”物质。纯格氏试剂在乙醚溶液中的比率2 [“ RMgX”] / [“ R 2 Mg”]的值是：C 6 F 5 MgBr，1·0；C 6 F 5 MgBr，1·0。C 6 F 5 MgCl，2·0； m / z。C 6 F 5 Mgl，1·4；C 6 F 5 Mgl，1·4。3-F，5，4Cl 2 C 6 H 2 ·MgBr，约。2·5; C 10 H 6 FMgl，20; p -F·C 6 H 4 ·MgBr，20；p -F·C 6 H 4 ·Mgl 20.关于这些“ RMgX”和“ R 2 Mg”物质的性质的有限的附加信息已从氟化学位移获得。氟芳基交换速率定性地遵循以下顺序：C 6 F 5 Mgl
• Method of dissolving contaminants from substrates by using
  申请人：AlliedSignal Inc.

  公开号：US05298083A1

  公开（公告）日：1994-03-29

  The present invention provides hydrofluorocarbon solvents having a portion which is fluorocarbon and the remaining portion is hydrocarbon and having 4 to 7 carbon atoms. The solvents are useful for dissolving contaminants or removing contaminants from the surface of a substrate.

  本发明提供了一种氢氟烃溶剂，其中一部分为氟碳化合物，其余部分为碳氢化合物，碳数为4至7个。这些溶剂可用于溶解污染物或从基底表面去除污染物。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: F: PerFHalOrg.4, 2.2.4, page 68 - 115
  作者：

  DOI：——

  日期：——
• A model of therapeutic intervention with Indigenous Australians
  作者：David Vicary、Henry Andrews

  DOI：10.1111/j.1467-842x.2001.tb00592.x

  日期：2001.8

  Many non-Aboriginal mental health practitioners are confronted by the lack of practical information pertaining to interventions with Aboriginal clientele. Subsequently, this may have engendered uncertainty in potential therapists and counsellors due to the lack of reliable, practical and culturally appropriate information. Those non-Aboriginal mental health practitioners working in the field with Aboriginal clients do so with varying degrees of success and build upon their knowledge base through personal experience and anecdotal information. Unfortunately, this information is often not made available to others working in the field through journal publication. This Practice Note examines a model of intervention aimed at developing relationships to enhance therapeutic interventions at the individual, family and systems level. As a way of clarification, the model is described via a case study involving a psychological intervention with a remote Aboriginal community.