2-amino-1-(4-propyl-phenyl)-propan-1-one; hydrochloride | 100369-09-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-amino-1-(4-propyl-phenyl)-propan-1-one; hydrochloride
• 英文别名: 2-Amino-1-(4-propyl-phenyl)-propan-1-on; Hydrochlorid；2-Amino-1-(4-propylphenyl)propan-1-one;hydrochloride；2-amino-1-(4-propylphenyl)propan-1-one;hydrochloride
• CAS: 100369-09-3
• 化学式: C₁₂H₁₇NO*ClH
• 分子量: 227.734
• InChiKey: QHVQKBSQKQEJJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.59
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  43.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-amino-1-(4-propyl-phenyl)-propan-1-one; hydrochloride 、 环己基异氰酸酯 在 三乙胺 作用下， 以 丙酮 为溶剂， 生成
  参考文献：
  名称：

  5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  摘要：

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.12.064
• 作为产物：
  描述：

  2,2,2-trifluoro-N-(1-oxo-1-(4-propylphenyl)propan-2-yl)acetamide 在 盐酸 作用下， 以 乙醇 为溶剂， 生成 2-amino-1-(4-propyl-phenyl)-propan-1-one; hydrochloride
  参考文献：
  名称：

  5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  摘要：

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.12.064

文献信息

• 5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity
  作者：Kazutoshi Watanabe、Yasuhiro Morinaka、Yoshio Hayashi、Masaki Shinoda、Hiroyoshi Nishi、Nobuko Fukushima、Toshiaki Watanabe、Akira Ishibashi、Satoshi Yuki、Masahiko Tanaka

  DOI：10.1016/j.bmcl.2007.12.064

  日期：2008.2

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.