8-chloro-3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorooctan-1-ol | 101829-19-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 8-chloro-3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorooctan-1-ol
• CAS: 101829-19-0
• 化学式: C₈H₅ClF₁₂O
• 分子量: 380.561
• InChiKey: DJFNKHNGUCCSDR-UHFFFAOYSA-N

物化性质

• 沸点：
  76-78 °C(Press: 5 Torr)
• 密度：
  1.618±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.38
• 重原子数：
  22.0
• 可旋转键数：
  7.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  8-chloro-3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorooctan-1-ol 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 生成 3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorooctanol
  参考文献：
  名称：

  Mesomorphic Properties of Some Liquid Crystals with Semifluorocarbon Chains

  摘要：

  Three series of chiral compounds with semifluorocarbon chains have been synthesized. These compounds were characterized by infra-red spectra (IR), H-1 nuclear magnetic resonance (H-1 NMR), F-19 nuclear magnetic resonance (F-19 NMR), mass spectra (MS), and elemental analysis. Their phase-transition behavior was investigated by differential scanning calorimeter (DSC) and polarizing optical microscopy. To a certain compound, when the terminal hydrogen atom in the semi-fluoroalkyl chain was substituted by a chlorine atom, both the clearing point and the melting point were increased and the thermal stability of the SmC phase was enhanced. Moreover, with the introduction of a triple bond in the core, both the melting point and the clearing point were increased.

  DOI：

  10.1080/15421400701613458
• 作为产物：
  描述：

  1-Chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluoro-8-iodooctane 在 硫酸 、 sodium sulfite 作用下， 反应 1.0h， 以75%的产率得到8-chloro-3,3,4,4,5,5,6,6,7,7,8,8-dodecafluorooctan-1-ol
  参考文献：
  名称：

  Mesomorphic Properties of Some Liquid Crystals with Semifluorocarbon Chains

  摘要：

  Three series of chiral compounds with semifluorocarbon chains have been synthesized. These compounds were characterized by infra-red spectra (IR), H-1 nuclear magnetic resonance (H-1 NMR), F-19 nuclear magnetic resonance (F-19 NMR), mass spectra (MS), and elemental analysis. Their phase-transition behavior was investigated by differential scanning calorimeter (DSC) and polarizing optical microscopy. To a certain compound, when the terminal hydrogen atom in the semi-fluoroalkyl chain was substituted by a chlorine atom, both the clearing point and the melting point were increased and the thermal stability of the SmC phase was enhanced. Moreover, with the introduction of a triple bond in the core, both the melting point and the clearing point were increased.

  DOI：

  10.1080/15421400701613458

文献信息

• LU, HENG-YAO;GUO, CAI-YUN;WANG, SHAN-DRI;CHEN, QING-YUN, ACTA CHIM. SIN., 1985, 43, N 10, 970-975
  作者：LU, HENG-YAO、GUO, CAI-YUN、WANG, SHAN-DRI、CHEN, QING-YUN

  DOI：——

  日期：——
• Mesomorphic Properties of Some Liquid Crystals with Semifluorocarbon Chains
  作者：Haitao Li、Jianxun Wen、Yonggang Yang

  DOI：10.1080/15421400701613458

  日期：2007.10.22

  Three series of chiral compounds with semifluorocarbon chains have been synthesized. These compounds were characterized by infra-red spectra (IR), H-1 nuclear magnetic resonance (H-1 NMR), F-19 nuclear magnetic resonance (F-19 NMR), mass spectra (MS), and elemental analysis. Their phase-transition behavior was investigated by differential scanning calorimeter (DSC) and polarizing optical microscopy. To a certain compound, when the terminal hydrogen atom in the semi-fluoroalkyl chain was substituted by a chlorine atom, both the clearing point and the melting point were increased and the thermal stability of the SmC phase was enhanced. Moreover, with the introduction of a triple bond in the core, both the melting point and the clearing point were increased.