3,7-二甲基-2,3-亚甲基-6-辛烯-1-醛 | 904929-41-5

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氧化物
• 中文名称: 3,7-二甲基-2,3-亚甲基-6-辛烯-1-醛
• 英文名称: 3,7-dimethyl-2,3-methylene-6-octen-1-al
• 英文别名: 2-methyl-2-(4-methyl-pent-3-enyl)-cyclopropanecarbaldehyde；2-methyl-2-(4-methylpent-3-enyl)cyclopropane-1-carbaldehyde
• CAS: 904929-41-5
• 化学式: C₁₁H₁₈O
• 分子量: 166.263
• InChiKey: HVRSGXFUZOKZNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,7-二甲基-2,3-亚甲基-6-辛烯-1-醛 在 sodium ethanolate 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 20.0h， 生成 ethyl (2E,4E)-6,7-methylene-3,7,11-trimethyl-2,4,10-dodecatrienoate
  参考文献：
  名称：

  Sobotka, Wieslaw; Chojecka-Koryn, Ewa, Bulletin of the Polish Academy of Sciences: Chemistry, 1984, vol. 32, # 3-6, p. 207 - 216

  摘要：

  DOI：
• 作为产物：
  描述：

  OBM 2979 在 pyridinium chlorochromate 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以80.2%的产率得到3,7-二甲基-2,3-亚甲基-6-辛烯-1-醛
  参考文献：
  名称：

  Sobotka, Wieslaw; Chojecka-Koryn, Ewa, Bulletin of the Polish Academy of Sciences: Chemistry, 1984, vol. 32, # 3-6, p. 207 - 216

  摘要：

  DOI：

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• Synthesis of Highly Functionalized Cyclohexenone Rings: Rhodium-Catalyzed 1,3-Acyloxy Migration and Subsequent [5+1] Cycloaddition
  作者：Dongxu Shu、Xiaoxun Li、Min Zhang、Patrick J. Robichaux、Weiping Tang

  DOI：10.1002/anie.201006881

  日期：2011.2.7

  from cyclopropyl‐substituted propargyl esters by using a [Rh(CO)2Cl}2] catalyst. This metal catalyst promoted the 1,3‐acyloxy migration of propargyl esters and a subsequent [5+1] cycloaddition of the resulting allenylcyclopropanes in the presence of CO with high regioselectivity.

  Lead Rh-ole：通过使用 [Rh(CO) 2 Cl} 2 ] 催化剂，由环丙基取代的炔丙酯制备高度取代的环己烯酮。这种金属催化剂在 CO 存在下促进了炔丙酯的 1,3-酰氧基迁移和随后得到的烯丙基环丙烷的 [5+1] 环加成反应，具有高区域选择性。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• Cyclopropanecarbonitriles and their use in perfume compositions
  申请人：Narula P.S. Anubhav

  公开号：US20060287204A1

  公开（公告）日：2006-12-21

  The present invention is directed to novel cyclopropanecarbonitrile compounds of the general formula wherein R is a hydrogen, or a straight, branched, or cyclic hydrocarbon moiety consisting of 1 to 30 carbon atoms and containing single and/or double bonds; R1 is a hydrogen or a straight, branched, or cyclic hydrocarbon moiety consisting of 1 to 30 carbon atoms and containing single and/or double bonds and R2 is a hydrogen or a straight, branched, or cyclic hydrocarbon moiety consisting of 1 to 30 carbon atoms and containing single and/or double bonds.

  本发明涉及通式的新型环丙烷腈化合物，其中R是氢，或者由1到30个碳原子组成的直链、支链或环烃基，含有单键和/或双键；R1是氢或者由1到30个碳原子组成的直链、支链或环烃基，含有单键和/或双键，R2是氢或者由1到30个碳原子组成的直链、支链或环烃基，含有单键和/或双键。
• Aromachemicals
  申请人：Turin Luca

  公开号：US20070276152A1

  公开（公告）日：2007-11-29

  A compound or mixture of compounds of formulae: wherein R 1 and R 2 are each independently H or CH 3 .

  一个化学式为的化合物或混合物：其中R1和R2分别独立地为H或CH3。