甲基三烯丙基硅烷 | 1112-91-0

• 物质功能分类: 化学试剂 - 有机试剂 - 硅烷
• 分子结构分类: 有机化合物 - 碳氢化合物衍生物
• 中文名称: 甲基三烯丙基硅烷
• 英文名称: methyltriallylsilane
• 英文别名: triallylmethylsilane；Methyl-triallylsilan；Triallyl-methyl-silan；methyl-tris(prop-2-enyl)silane
• CAS: 1112-91-0
• 化学式: C₁₀H₁₈Si
• mdl: MFCD00800604
• 分子量: 166.338
• InChiKey: JFCCVNTYPIUJDJ-UHFFFAOYSA-N

物化性质

• 熔点：
  60-75 °C
• 沸点：
  95 °C (52 mmHg)
• 密度：
  0.8055 g/cm3
• 闪点：
  22 °C
• 最大波长(λmax)：
  199nm(lit.)
• 稳定性/保质期：
  避免与不相容的材料接触。

计算性质

• 辛醇/水分配系数(LogP)：
  4.17
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险等级：
  3
• 危险品标志：
  Xi
• 安全说明：
  S16,S26,S37/39
• 危险类别码：
  R36/37/38
• 海关编码：
  2931900090
• 危险品运输编号：
  UN 1993 3/PG III
• 包装等级：
  III
• 危险类别：
  3
• 危险性防范说明：
  P501,P240,P210,P233,P243,P241,P242,P264,P280,P370+P378,P337+P313,P305+P351+P338,P362+P364,P303+P361+P353,P332+P313,P403+P235
• 危险性描述：
  H315,H319,H225
• 储存条件：
  密封储存，应存放在阴凉、干燥的库房中，并远离火源和易燃易爆区域。

SDS

Name:	Methyltriallylsilane Material Safety Data Sheet
Synonym:	None known
CAS:	1112-91-0

Section 1 - Chemical Product MSDS Name:Methyltriallylsilane Material Safety Data Sheet
Synonym:None known

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
1112-91-0	Methyltriallylsilane	ca 100	unlisted

Hazard Symbols: T
Risk Phrases: 23/24/25 48

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Danger of serious damage to health by prolonged exposure.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Toxic in contact with skin.
Ingestion:
May cause irritation of the digestive tract. Poison by ingestion.
The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Toxic if inhaled.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily.
Extinguishing Media:
Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Cool containers with flooding quantities of water until well after fire is out.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1112-91-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: colorless
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 95 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H18Si
Molecular Weight: 166.2115

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, oxides of silicon.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1112-91-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Methyltriallylsilane - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
IMO
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
RID/ADR
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing group: III

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 48 Danger of serious damage to health by prolonged
exposure.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 37 Wear suitable gloves.
S 38 In case of insufficient ventilation, wear
suitable respiratory equipment.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1112-91-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 1112-91-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1112-91-0 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  甲基三烯丙基硅烷 在 dihydrogen hexachloroplatinate 吡啶 、 cyclohexylborane 作用下， 以 四氢呋喃 为溶剂， 反应 30.0h， 生成 tris(3-((3-methylsulfonyloxypropyl)dimethylsilyl)propyl)methylsilane
  参考文献：
  名称：

  Syntheses and Vero toxin-binding activities of carbosilane dendrimers periphery-functionalized with galabiose

  摘要：

  Carbosilane dendrimers bearing galabiose (Gal alpha 1-4Gal) with three, four, and six galabiose units at the periphery of the dendrimers were synthesized for use as artificial inhibitors against Shiga toxins (Stxs) produced by Escherichia coli O157:H7. The galabiose unit, prepared from penta-O-acetyl-beta-D-galactopyranose, was linked with carbosilane dendrimers of three shapes to afford acety I-protected glycodendrimers in good yields. De-O-acetylation of the clusters was carried out in the presence of NaOMe and then aq NaOH to give the desired three shapes of galabiose-coated carbosilane dendrimers. Their biological activities toward Stxs were evaluated by kinetic analysis, binding assays, and cytotoxic assays. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.03.042
• 作为产物：
  描述：

  甲基三氯硅烷 、 3-溴丙烯 在 Mg 作用下， 以 not given 为溶剂， 以61%的产率得到甲基三烯丙基硅烷
  参考文献：
  名称：

  Bazhulin, P. A.; Egorov, Ju. P.; Mironov, V. F., Doklady Akademii Nauk SSSR, 1953, vol. 92, p. 515 - 517

  摘要：

  DOI：

文献信息

• Controlled introduction of allylic group to chlorosilanes
  作者：Zhifang Li、Xiaojun Cao、Guoqiao Lai、Jinhua Liu、Yong Ni、Jirong Wu、Huayu Qiu

  DOI：10.1016/j.jorganchem.2006.07.023

  日期：2006.11

  controlled manner. Thus allylation of trisubstituted chlorosilanes (R3SiCl) afforded a variety of aryl, aralkyl, and alkenyl substituted allylsilanes. Dichlorosilanes (R2SiCl2) can either afford monoallylated silanes or diallylated silanes depending on the amount of allylsamarium bromide used. Similarly, trichlorosilanes (RSiCl3) can selectively afford mono-, di-, and tri-allylation products. Finally

  用烯丙基溴化mar已经实现了氯硅烷的烯丙基化，特别是以可控的方式。因此，三取代的氯硅烷（R 3 SiCl）的烯丙基化得到各种芳基，芳烷基和烯基取代的烯丙基硅烷。根据所用的烯丙基溴化amount的量，二氯硅烷（R 2 SiCl 2）既可以提供单烯丙基化的硅烷，也可以提供二烯丙基化的硅烷。类似地，三氯硅烷（RSiCl 3）可以选择性提供单，二和三烯丙基化产物。最后，使全氯硅烷（SiCl 4）逐步烯丙基化，并以令人满意的产率获得相应的分别含有一个，两个，三个或四个烯丙基的硅烷。
• 有機ケイ素化合物
  申请人：信越化学工業株式会社

  公开号：JP2015124170A

  公开（公告）日：2015-07-06

  【課題】新規なアルケニル基と２個の加水分解性シリル基とを有する有機ケイ素化合物の提供。【解決手段】一般式（１）で示される有機ケイ素化合物。（Ｒ1、Ｒ2は独立に炭素数１〜１０の非置換又は置換の１価炭化水素基、Ｒ3は独立に２価炭化水素基、Ｘは独立にハロゲン原子、アルコキシ基、ハロゲン化アルコキシ基、アルコキシ基置換アルコキシ基、アルケニルオキシ基及びアセトキシ基から選ばれる加水分解性基、ａは独立に２又は３、ｂは０〜４の整数）【選択図】なし

  提供具有新型烯基和两个可水解硅基的有机硅化合物。通过通式（1）表示的有机硅化合物。（R1、R2分别独立地是1-10个碳原子的非取代或取代的一价碳氢基，R3独立地是二价碳氢基，X独立地是卤素原子、醚基、卤代醚基、醚基取代的醚基、烯基氧基和乙酰氧基中选择的可水解基，a独立地是2或3，b是0~4的整数）【选择图】无
• Reactivity of Hypervalent Species: Reactions of Anionic Penta-Coordinated Silicon Complexes towards Nucleophiles
  作者：Alain Boudin、Geneviève Cerveau、Claude Chuit、Robert J. P. Corriu、Catherine Reye

  DOI：10.1246/bcsj.61.101

  日期：1988.1

  The reactivity of anionic penta-coordinated silicon complexes [RSi(O2C6H4-o)2]−Na+ 1 with nucleophilic reagents has been studied. 1 can be reduced to organosilanes RSiH3 by metallic hydrides. Reactions with an excess of Grignard or organolithium reagents (R′MgX or R′Li) gave tetraorganosilanes RSiR′3. When only two molar equivalents of Grignard reagents (R′MgX) or lithium reagents (R′Li) are added

  已经研究了阴离子五配位硅配合物 [RSi(O2C6H4-o)2]-Na+1 与亲核试剂的反应性。1 可以被金属氢化物还原为有机硅烷 RSiH3。与过量的格氏试剂或有机锂试剂（R'MgX 或 R'Li）反应得到四有机硅烷 RSiR'3。当仅将两摩尔当量的格氏试剂 (R'MgX) 或锂试剂 (R'Li) 添加到配合物 1 时，可以制备功能性硅烷 RR'2SiX。
• Self-Replication and Amplification of Enantiomeric Excess of Chiral Multifunctionalized Large Molecules by Asymmetric Autocatalysis
  作者：Tsuneomi Kawasaki、Mai Nakaoda、Yutaro Takahashi、Yusuke Kanto、Nanako Kuruhara、Kenji Hosoi、Itaru Sato、Arimasa Matsumoto、Kenso Soai

  DOI：10.1002/anie.201405441

  日期：2014.10.13

  including the chirality of newly formed asymmetric carbon atoms, in the reaction of the corresponding achiral aldehydes and reagent. The chirality of the large multifunctionalized molecules controlled the enantioselectivity of the reaction in a highly selective manner to construct multiple asymmetric stereogenic centers in a single reaction.

  大型手性分子结构的自我复制是合成，系统和益生元化学中的巨大挑战和关注之一。本文描述的是一种新的化学系统，其中大的手性多官能分子具有不对称的自催化自复制和自我改良能力，即除非对映异构体比例外，其对映体富集度得到改善。大手性多官能分子在相应的非手性醛与试剂的反应中催化具有相同结构的自身生成，包括新形成的不对称碳原子的手性。
• Zinc mediated allylations of chlorosilanes promoted by ultrasound: Synthesis of novel constrained sila amino acids
  作者：Remya Ramesh、D. Srinivasa Reddy

  DOI：10.1039/c4ob00294f

  日期：——

  A simple, fast and efficient method for allylation and propargylation of chlorosilanes through zinc mediation and ultrasound promotion is reported. As a direct application of the resulting bis-allylsilanes, three novel, constrained sila amino acids are prepared for the first time.

  通过锌介导和超声波促进，报道了一种用于氯硅烷的烯基化和丙炔基化的简单、快速和高效方法。作为产生的双烯基硅烷的直接应用，首次制备了三种新颖的约束硅氨基酸。