ethyl 1-[(2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]prop-2-enyl carbonate | 198060-33-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: ethyl 1-[(2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]prop-2-enyl carbonate
• CAS: 198060-33-2
• 化学式: C₄₀H₄₄O₈
• 分子量: 652.785
• InChiKey: SIYXKMARJONIOW-HSGFMYCYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  48
• 可旋转键数：
  19
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  81.7
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  苄胺 、 ethyl 1-[(2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]prop-2-enyl carbonate 在 bis[1,2-bis(diphenylphosphino)ethane]palladium(0) 作用下， 生成 (E)-N-benzyl-3-[(2S,3S,4R,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]prop-2-en-1-amine
  参考文献：
  名称：

  A Pd(0)-catalyzed route to functionalized β-C-glycosides from β-C-glycosylaldehydes

  摘要：

  C-glycosides are synthesized in five steps starting from beta-C-glycosylaldehydes 1 and 2. The key step is a Pd(0)-catalyzed alkylation that leads regio and stereoselectively to exotic compounds by formation of C-C and C-N bonds. (C) 1997 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10067-3
• 作为产物：
  描述：

  在 喹啉 、 palladium, 5% on calcium carbonate, poisoned with lead 吡啶 、 氢气 、 potassium carbonate 作用下， 以 甲醇 、 二氯甲烷 、 乙酸乙酯 为溶剂， 生成 ethyl 1-[(2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]prop-2-enyl carbonate
  参考文献：
  名称：

  A Pd(0)-catalyzed route to functionalized β-C-glycosides from β-C-glycosylaldehydes

  摘要：

  C-glycosides are synthesized in five steps starting from beta-C-glycosylaldehydes 1 and 2. The key step is a Pd(0)-catalyzed alkylation that leads regio and stereoselectively to exotic compounds by formation of C-C and C-N bonds. (C) 1997 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10067-3

文献信息

• A Pd(0)-catalyzed route to functionalized β-C-glycosides from β-C-glycosylaldehydes
  作者：Veronique Michelet、Jean-Pierre Genêt、Gilles Dujardin

  DOI：10.1016/s0040-4039(97)10067-3

  日期：1997.11

  C-glycosides are synthesized in five steps starting from beta-C-glycosylaldehydes 1 and 2. The key step is a Pd(0)-catalyzed alkylation that leads regio and stereoselectively to exotic compounds by formation of C-C and C-N bonds. (C) 1997 Published by Elsevier Science Ltd.