phenyl 3,5-di-t-butyl-4-hydroxystyryl ketone | 135040-07-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: phenyl 3,5-di-t-butyl-4-hydroxystyryl ketone
• 英文别名: beta-Benzoyl-3,5-di-tert-butyl-4-hydroxystyrene；(E)-3-(3,5-ditert-butyl-4-hydroxyphenyl)-1-phenylprop-2-en-1-one
• CAS: 135040-07-2
• 化学式: C₂₃H₂₈O₂
• 分子量: 336.474
• InChiKey: MQLALXSEENATJA-OUKQBFOZSA-N

物化性质

• 沸点：
  436.8±37.0 °C(Predicted)
• 密度：
  1.046±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  phenyl 3,5-di-t-butyl-4-hydroxystyryl ketone 、 重氮甲烷 以 乙醚 为溶剂， 以63%的产率得到3-benzoyl-4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-pyrazoline
  参考文献：
  名称：

  Dinoiu, Vasile; Cǎproiu, Miron Teodor; Drǎghici, Constantin, Revue Roumaine de Chimie, 2005, vol. 50, # 1, p. 47 - 51

  摘要：

  DOI：
• 作为产物：
  描述：

  苯乙酮 、 3,5-二叔丁基-4-羟基苯甲醛 在 acid 作用下， 生成 phenyl 3,5-di-t-butyl-4-hydroxystyryl ketone
  参考文献：
  名称：

  亲电烯烃的选择性阳极氟化

  摘要：

  某些亲电子烯烃（与吸电子基团共轭），肉桂酸乙酯，RC 6 H 4 CHCHCO 2 Et（R = H，CH 3，CH 3 O，F和CF 3），肉桂腈，C 6 H 4 CHCHCN的阳极氟化使用氟化铵作为氟源和支持电解质，在CH 2 Cl 2中作为电解质，使用苯基苯乙烯基酮和叔丁基苯乙烯基酮，可得到预期的邻位二氟化合物，为赤型和苏型异构体的混合物。苯基3,5-二-的阳极氟化叔丁基-4-羟基苯乙烯基酮产生两种单氟化合物。讨论了可能的反应机理。

  DOI：

  10.1016/j.jfluchem.2005.02.021

文献信息

• An anti-inflammatory, analgesic, and antipyretic pharmaceutical composition, and method for producing it
  申请人：KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0057881A2

  公开（公告）日：1982-08-18

  A new anti-inflammatory, analgesic, and antipyretic pharmaceutical composition is disclosed which contains a 3,5-di-tert-butyl-4-hydroxystyrene derivative of the formula: wherein R' stands for a group represented by COR3 [R3 denotes a group of OR4 (R4 is a hydrogen atom or an alky group with C1 ~ C4), an alkyl group with C, - C3, a pheny group, or an amino group], a nitro group, or an alkylsulfony group represented by SO2R5 (R5 is an alkyl group with C, - C3); and R2 stands for a hydrogen atom, an alkyl group witt C, - C4, a hydroxyalkyl group with C1 ~ C4, a cyano group, o an acyl group represented by COR6 (R6 is an alkyl group witt C, - C3), or its pharmaceutically acceptable salt as an active ingre dient in association with pharmaceutical excipients, and method for producing it.

  本发明公开了一种新的消炎、镇痛和解热药物组合物，其中含有一种 3,5-二叔丁基-4-羟基苯乙烯衍生物，其式为 其中 R' 代表 COR3[R3 表示 OR4（R4 是氢原子或 C1 ~ C4 的烷基）、C, - C3 的烷基、苯基或氨基]、硝基或 SO2R5（R5 是 C, - C3 的烷基）代表的烷基锍基团；和 R2 代表氢原子、C, - C4 的烷基、C1 ~ C4 的羟烷基、氰基或由 COR6 代表的酰基（R6 是 C, - C3 的烷基），或其药学上可接受的盐，作为与药用辅料结合的活性成分，以及其生产方法。
• ARNOLDI, ANNA;CARUGHI, MARICA;FARINA, GANDOLFINA;MERLINI, LUCIO;PARRINO, +, J. AGR. AND FOOD CHEM., 37,(1989) N, C. 508-512
  作者：ARNOLDI, ANNA、CARUGHI, MARICA、FARINA, GANDOLFINA、MERLINI, LUCIO、PARRINO, +

  DOI：——

  日期：——
• KATSUMI, IKUO;KONDO, HIDEO;FUSE, YOSHIHIDE;YAMASHITA, KATSUJI;HIDAKA, TAK+, CHEM. AND PHARM. BULL., 1986, 34, N 4, 1619-1627
  作者：KATSUMI, IKUO、KONDO, HIDEO、FUSE, YOSHIHIDE、YAMASHITA, KATSUJI、HIDAKA, TAK+

  DOI：——

  日期：——
• HYDROXYL-FUNCTIONAL UNSATURATED POLYAMINE SILICONE LIGAND SUITABLE FOR QUANTUM DOT COMPOSITIONS AND ARTICLES
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US20200216752A1

  公开（公告）日：2020-07-09

  A quantum dot article comprises (a) a first barrier layer, (b) a second barrier layer, and (c) a quantum dot layer between the first barrier layer and the second barrier layer, the quantum dot layer comprises light-emitting nanoparticles dispersed in a cured matrix; wherein the quantum dot layer further comprises a hydroxyl-functional unsaturated polyamine silicone ligand that is the reaction product of a polyamine silicone ligand and an unsaturated monofunctional epoxy compound.
• HYDROXYL-FUNCTIONAL POLYAMINE SILICONE LIGAND SUITABLE FOR QUANTUM DOT COMPOSITIONS AND ARTICLES
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US20200262979A1

  公开（公告）日：2020-08-20

  A quantum dot article is described comprising a first barrier layer, a second barrier layer, and a quantum dot layer between the first and second barrier layer. The quantum dot layer comprises light-emitting nanoparticles dispersed in a cured matrix. The quantum dot layer further comprises a hydroxyl-iunctional polyamine silicone ligand that is the reaction product of a polyamine silicone ligand and a monofunctional epoxy compound. Also described is a hydroxyl-functional polyamine silicone that is the reaction product of a polyamine silicone and a monofunctional epoxy compound, as well as quantum dot compositions comprising light-emitting nanoparticles and the described hydroxyl-functional polyamine silicone.