2,8-Di(2-furyl)quinoline | 133042-66-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2,8-Di(2-furyl)quinoline
• 英文别名: 2,8-bis(furan-2-yl)quinoline
• CAS: 133042-66-7
• 化学式: C₁₇H₁₁NO₂
• 分子量: 261.28
• InChiKey: ZXKRMHQANPEWHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  8-羟基喹啉 在 焦硫酰氟 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 2,8-Di(2-furyl)quinoline
  参考文献：
  名称：

  Palladium cross-coupling reactions of aryl fluorosulfonates: an alternative to triflate chemistry

  摘要：

  A new and efficient electrophilic partner for palladium(O)-catalyzed cross coupling is reported. Aryl fluorosulfonates are readily prepared in high yield by treatment of the appropriate phenol with fluorosulfonate anhydride. The palladium-catalyzed coupling reactions of these fluorosulfonates with vinyl- and aryltin reagents, as well as organozinc chlorides, takes place under mild conditions in a regio- and stereoselective manner.

  DOI：

  10.1021/jo00011a010

文献信息

• ROTH, GREGORY P.;FULLER, CARL E., J. ORG. CHEM., 56,(1991) N1, C. 3493-3496
  作者：ROTH, GREGORY P.、FULLER, CARL E.

  DOI：——

  日期：——
• Palladium cross-coupling reactions of aryl fluorosulfonates: an alternative to triflate chemistry
  作者：Gregory P. Roth、Carl E. Fuller

  DOI：10.1021/jo00011a010

  日期：1991.5

  A new and efficient electrophilic partner for palladium(O)-catalyzed cross coupling is reported. Aryl fluorosulfonates are readily prepared in high yield by treatment of the appropriate phenol with fluorosulfonate anhydride. The palladium-catalyzed coupling reactions of these fluorosulfonates with vinyl- and aryltin reagents, as well as organozinc chlorides, takes place under mild conditions in a regio- and stereoselective manner.