3-(二硫代羧基硫代)丙酸 | 90980-77-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-(二硫代羧基硫代)丙酸
• 英文名称: 3-Dithiocarboxysulfanylpropanoic acid
• CAS: 90980-77-1
• 化学式: C₄H₆O₂S₃
• 分子量: 182.288
• InChiKey: QCXYRIKNUUVLLG-UHFFFAOYSA-N

物化性质

• 沸点：
  330.9±44.0 °C(Predicted)
• 密度：
  1.491±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  95.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-(二硫代羧基硫代)丙酸 、 溴甲苯 以 丙酮 为溶剂， 生成 3-[[(苄硫基)硫代羰基]硫基]丙酸
  参考文献：
  名称：

  Facile one pot synthesis of a range of reversible addition–fragmentation chain transfer (RAFT) agents

  摘要：

  本文描述了一种通用合成策略的应用，实现了高产量、简便合成多种功能性RAFT试剂，包括三硫代碳酸盐、黄原酸盐和二硫代氨基甲酸盐。

  DOI：

  10.1039/b804260h
• 作为产物：
  描述：

  二硫化碳 、 3-巯基丙酸 在 potassium phosphate 作用下， 以 丙酮 为溶剂， 反应 0.33h， 生成 3-(二硫代羧基硫代)丙酸
  参考文献：
  名称：

  Synthesis of triblock copolymers composed of poly(vinylidene fluoride-co-hexafluoropropylene) and ionic liquid segments

  摘要：

  通过使用具有末端官能团的氟聚物作为宏观链转移剂，通过可逆加成断裂链转移（RAFT）聚合咪唔甲酯单体，制备了一类含有离子液体的新型三嵌段共聚物。研究发现阴离子反离子对聚合物的热性能、离子导电性和链段动力学有直接影响。离子导电性的温度依赖性可以很好地由Vogel-Tamman-Fulcher模型描述，这表明离子运动与链段运动紧密耦合。

  DOI：

  10.1039/c1jm14971g

文献信息

• Design of multi-functional linear polymers that capture and neutralize a toxic peptide: a comparison with cross-linked nanoparticles
  作者：Yusuke Wada、Haejoo Lee、Yu Hoshino、Shunsuke Kotani、Kenneth J. Shea、Yoshiko Miura

  DOI：10.1039/c4tb01967a

  日期：——

  In this paper, a library of multi-functional linear poly-N-isopropylacrylamide (pNIPAm) polymers having a range of molecular weights and functional groups were synthesized and their interaction with the hemolytic peptide, melittin, was examined.

  在这篇论文中，合成了一组具有多功能的线性聚异丙基丙烯酰胺（pNIPAm）聚合物库，其具有一系列分子量和功能基团，并研究了它们与溶血肽melittin的相互作用。
• RAFT polymerization of N-vinylcaprolactam and effects of the end group on the thermal response of poly(N-vinylcaprolactam)
  作者：Lidong Shao、Minqi Hu、Lin Chen、Li Xu、Yunmei Bi

  DOI：10.1016/j.reactfunctpolym.2012.04.002

  日期：2012.6

  The reversible addition-fragmentation chain transfer (RAFT) radical polymerization of N-vinylcaprolactam (NVCL) was performed using either S-benzyl-S-(benzyl propionate) trithiocarbonate (CTA 1) or N, N-diethyl-S-(alpha,alpha'- dimethyl-alpha ''-acetic acid) dithiocarbamate (CTA 2) as a chain transfer agent (CTA). The polymerizations were controlled processes that yielded polymers with high conversion (>60%), controlled molecular weights that were close to the theoretical values and a narrow molecular weight distribution (minimal value: 1.13). The cloud point temperatures of poly(N-vinylcaprolactam) (PNVCL) were measured by turbidimetry and shifted to lower temperature and concentrations as the hydrophobicity of the end groups and the molecular weights of the polymers increased. (C) 2012 Elsevier Ltd. All rights reserved.
• Facile one pot synthesis of a range of reversible addition–fragmentation chain transfer (RAFT) agents
  作者：Jared Skey、Rachel K. O’Reilly

  DOI：10.1039/b804260h

  日期：——

  The application of a universal synthetic strategy for the high yielding and facile synthesis of a wide range of functional RAFT agents including trithiocarbonates, xanthates and dithiocarbamates is described.

  本文描述了一种通用合成策略的应用，实现了高产量、简便合成多种功能性RAFT试剂，包括三硫代碳酸盐、黄原酸盐和二硫代氨基甲酸盐。
• Synthesis of triblock copolymers composed of poly(vinylidene fluoride-co-hexafluoropropylene) and ionic liquid segments
  作者：Chalathorn Chanthad、Kevin A. Masser、Kui Xu、James Runt、Qing Wang

  DOI：10.1039/c1jm14971g

  日期：——

  A new class of ionic liquid-containing triblock copolymers have been prepared viaRAFT polymerization of the imidazolium methacrylate monomer using a telechelic fluoropolymer as the macro-chain transfer agent. It is found that the anionic counterion has a direct impact on the thermal properties, ionic conductivity and segmental dynamics of the polymers. The temperature dependence of the ionic conductivity is well described by the Vogel-Tamman-Fulcher model, suggesting that ion motion is closely coupled to segmental motion.

  通过使用具有末端官能团的氟聚物作为宏观链转移剂，通过可逆加成断裂链转移（RAFT）聚合咪唔甲酯单体，制备了一类含有离子液体的新型三嵌段共聚物。研究发现阴离子反离子对聚合物的热性能、离子导电性和链段动力学有直接影响。离子导电性的温度依赖性可以很好地由Vogel-Tamman-Fulcher模型描述，这表明离子运动与链段运动紧密耦合。