5-Ethyl-6-phenyl-azulene-1,2-dicarboxylic acid dimethyl ester | 143768-77-8

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 5-Ethyl-6-phenyl-azulene-1,2-dicarboxylic acid dimethyl ester
• 英文别名: Dimethyl 5-ethyl-6-phenylazulene-1,2-dicarboxylate
• CAS: 143768-77-8
• 化学式: C₂₂H₂₀O₄
• 分子量: 348.398
• InChiKey: CMBSLWGZEIYOCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  7-Ethyl-4-methoxy-5-methyl-1-phenyl-cyclohepta-1,3,5-triene 在 sodium methylate 、 四乙基对甲苯磺酸铵 作用下， 以 甲苯 为溶剂， 生成 5-Ethyl-6-phenyl-azulene-1,2-dicarboxylic acid dimethyl ester
  参考文献：
  名称：

  Regioselective synthesis of substituted tropones and azulenes using anodic oxidation of cycloheptatriene systems as the key reaction

  摘要：

  Regioselective synthesis of di- and trisubstituted tropones has been attained by utilizing anodic oxidation of cycloheptatriene systems as the key reaction. This anodic oxidation has also been found to be useful for the regioselective synthesis of mono- and disubstituted azulenes.

  DOI：

  10.1016/s0040-4039(00)74254-7

文献信息

• Regioselective synthesis of substituted tropones and azulenes using anodic oxidation of cycloheptatriene systems as the key reaction
  作者：Tatsuya Shono、Toshio Okada、Tsuyoshi Furuse、Shigenori Kashimura、Tetsuo Nozoe、Hirofumi Maekawa

  DOI：10.1016/s0040-4039(00)74254-7

  日期：1992.7

  Regioselective synthesis of di- and trisubstituted tropones has been attained by utilizing anodic oxidation of cycloheptatriene systems as the key reaction. This anodic oxidation has also been found to be useful for the regioselective synthesis of mono- and disubstituted azulenes.